Vol 52 No 11 November 2016
Institute of Animal Technology
Bulletin
G AWERB UK Report G Andrew Blake Tribute Award 2017
G CLAST Notice G Branch News
G Congress 2017 G Situations Vacant
G Suppliers Register G Diary Dates
EDITOR*
Sarah Lane
bulletineditor@iat.org.uk
ASSISTANT EDITOR*
Carole Wilson
bulletinassistant@iat.org.uk
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Bulletin
Vol 52 No 11 November 2016
Final copy date for
January Bulletin
1st December
The opinions expressed in the
Bulletin do not necessarily reflect
those of the Editor or the
Institute.
CONTENTS
AWERB UK Report 5-10
Congress 2017 10-11
Andrew Blake Tribute 12-13
Award 2017
Notice of IAT AGM 15
CLAST Notice 16-17
AS-ET 18,24-25
Named Persons’ 22-23
Workshop
Suppliers Register i-xliv
Branch News 33-40
Situations Vacant 41-42
Diary Dates 43
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November 2016
5
AWERB-UK
Delivering an effective AWERB Challenges and solutions
A forum for UK AWERB members organised by RSPCA, LASA, LAVA and IAT
Central London, Thursday, 12 May 2016
This meeting provided a forum for Animal Welfare and Ethical Review Body
(AWERB) members to discuss how they have made progress with respect to
achieving all of the AWERB’s tasks, compare experiences, discuss relevant topics
and identify any training needs. It was attended by 106 participants
representing a range of AWERB members including animal technologists,
project licence holders, Named Persons, lay and independent members.
The meeting agenda with links to speakers’ presentations and notes from the
ten workshops that were held on the day can be found at:
https://www.rspca.org.uk/webContent/staticImages/AWERBUK/AWERB_UK_output.
pdf
The content should be useful for members of AWERBs, Animal Welfare Bodies
and other ethics or animal care and use committees and to encourage others
to use this agenda as a template for running similar meetings to help progress
effective ethical review please contact research.animals@rspca.org.uk
if you
would like further information about how the meeting was convened and run.
The organisers plan to hold further AWERB-UK meetings and to follow up on
the various issues and conclusions raised by this first meeting; please use the
above email address if you have any comments on these or would like to be
kept informed about future initiatives.
The agenda was as follows:
1. Welcome and introduction Penny Hawkins, RSPCA
Morning session
2. Keynote presentation on the tasks of the AWERB Will Reynolds,
Head of Policy and Administration, Animals in Science Regulation Unit
Home Office
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3. Update on the Animals in Science Committee’s work on AWERBs
John Landers, ASC Chair
4. There were five workshops on selected AWERB tasks
Advise on the
application of
the 3Rs, and
keep [staff]
informed of
relevant
technical and
scientific
developments
Follow the
development
and outcome
(retrospective
review) of
projects; and
assist with
retrospective
assessment
Provide a
forum for
discussion and
development
of ethical
advice
Support
named
persons, and
other staff
dealing with
animals, on
animal
welfare,
ethical issues
and provision
of appropriate
training
Help to
promote a
‘culture of
care’ within
the
establishment
and, as
appropriate, in
the wider
community
Lunchtime ‘materials exchange’ session for sharing useful AWERB-related
resources
Afternoon session
Applying the 3Rs and improving practice a case study and discussion session
on using information from scientific developments to inform project review
and revise local practice
1. Aversion to carbon dioxide and inhalational anaesthesia in rodents Huw
Golledge, UFAW
Role-related discussions
2. Sessions for each broad ‘category’ of AWERB member each with a topic
chosen and session organised by the relevant body:
a) Chairs and Establishment Licence Holders (ELH) organised by ELH Forum
b) Animal technologists by IAT
c) Named Vets by LAVA
d) Other members by RSPCA
e) Scientists by LASA
The following is the outcome from the Animal Technologists workshop.
AWERB-UK Workshop on the role of the Named Animal Care and Welfare
Officer (NACWO) within the AWERB
Chairs: Ken Applebee and Sarah Lane, Institute for Animal Technology
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November 2016
The workshop began with a discussion on how the process of local ethical
review worked within different establishments, covering four main areas.
Processes
Participants shared their different experiences in relation to the process of
drafting and reviewing projects, including:
G A project team meeting takes place before the project licence is drafted,
involving the NACWO, Named Information Officer (NIO), Named Training
and Competency Officer (NTCO) and Named Veterinary Surgeon (NVS) and
the applicant.
G Applications involving zebrafish are reviewed by an expert(s) in their
husbandry and welfare before going for local ethical review.
G All amendments go through the full AWERB.
G The chair reads through all project licence applications (in addition to the
other AWERB members).
Engagement with scientists and the rest of the establishment
G Project licence applicants present their research or projects to the AWERB
verbally (for 10 minutes), explaining what the project involves and why they
wish to conduct the research.
G Another establishment reported a similar system, but with a template for
the presentation for consistency. At this establishment, researchers speak to
the AWERB twice a month.
G The AWERB holds a meeting monthly, with representation from the whole
site.
G Some participants felt that the AWERB had helped to build on relationships
between the NACWOs and NVS, creating a ‘team ethos’.
Establishment licence holders and Chairs
G Quite a number of participants had their establishment licence holder (ELH)
either chairing or sitting on the AWERB. It was felt that this enabled the
ELH to be more engaged.
G At one university, the AWERB chair provided funds for NACWO training
from an external provider (but they sat on both the AWERB and Biological
Services Unit (BSU) management group).
Problems
These mainly related to time constraints; for example;
G If paperwork is not received until a week before the meeting, there is little
time to review it properly.
G In any case, NACWOs may not have time to read the whole project licence
application.
G If resource was an issue preventing proper participation in the AWERB,
however, most participants would go to their BSU manager or ELH.
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The rest of the discussion focussed on the contribution that the NACWO can
make to the AWERB. The NACWO is expected to be an active member (see the
IAT’s NACWO Guidelines) and there was a great deal of interest in the AWERB-
UK meeting from NACWOs. In addition to the AWERB, a number of
establishments also had a NACWO meeting to allow free discussion. Several
issues were discussed at the workshop, including:
Training relevant to NACWOs who participate in the AWERB, especially in
statistics and experimental design. This is a major issue within the life sciences
at present and it would be helpful for NACWOs participating in the AWERB to
receive appropriate training in this topic. Some establishments have arranged
for statistics courses or talks for AWERB members. Others have brought in
scientists to provide training on statistics for the AWERB.
Relationships between NACWOs and lay or independent members. Participants
discussed their interactions with various types of ‘lay’ member, including
internal or external (the former being more common, e.g. someone from the
Press Office) and student representatives.
Positive changes that NACWOs had been able to introduce via the AWERB.
These included reducing the number of animals used for practicals, reducing
overbreeding and enabling more animal technologists to take up IAT training
courses.
Exchange of NACWOs between AWERBs the IAT already runs a successful
NACWO exchange programme, involving visits to other facilities but
participants felt that it would also be useful for NACWOs to attend AWERB
meetings at other establishments. It was suggested that this be put to the ASC
and extended to an exchange of all named people between different AWERBs.
Take home messages:
G Be an active participant in the AWERB it can help you contribute towards
improving both animal welfare and science within your establishment.
G If researchers do not regularly interact with or present to your AWERB, ask
whether this can be initiated.
G If you feel you are not properly supported in contributing to your AWERB,
e.g. if you do not have enough time to review paperwork, raise this with a
sympathetic member of staff.
G Consider what training you might need to help you contribute more
effectively, and ask for it!
G Mentor and support the independent/lay members, if they need it.
G Use the AWERB to request more resources for implementing the 3Rs locally.
G Think about taking part in the NACWO exchange programme and asking
for it to include sitting on the AWERB.
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November 2016
The meeting and its workshops were organised by:
Penny Hawkins and Maggy Jennings RSPCA
David Anderson LASA
Ken Applebee and Sarah Lane IAT
Ute Weyer and Ngaire Dennison LAVA
Brian Burlinson Envigo
Anne-Marie Farmer University of Cambridge
Pru Hobson-West University of Nottingham
Patrick Sinnett-Smith Pfizer
Jane Smith The Boyd Group
Charles Gentry Establishment Licence Holders’ Forum
The full report can be found at:
https://www.rspca.org.uk/webContent/staticImages/AWERBUK/AWERB_UK_output.
pdf
Editor
Reproduced from RSPCA
DATES NOT TO MISS!
It’s coming up to the busiest time of the year
so make sure you have these deadlines
marked on your calendar
NOVEMBER 2016
O 30th last chance to enter for the
prestigious ANDREW BLAKE TRIBUTE
AWARD 2017, to win a FREE
Congress, monetary prize and
plaque details overleaf
DECEMBER 2016
O 15th final date to receive the extra
discount to orally present your
poster
O 18th final date to be eligible for
Early Bird registration, saving £100!
O 30th final date for Exhibitors to
book a stand
JANUARY 2017
O 27th final date to complete a
Poster Submission form and receive
a discount
If you do not have a hard copy of the
‘Invitation Booklet’ download it at
http://www.iat.org.uk/#!congressc16th
To discuss any aspect of Congress with the Congress Committee or if you have
any questions, email congress@iat.org.uk
Check for updates www.iat.org.uk
Bulletin
November 2016
15
NOTICE of IAT ANNUAL
NOTICE of IAT ANNUAL
GENER
AL MEETING 2017
GENERAL MEETING 2017
The thirty-first Annual General Meeting of the
Institute of Animal Technology will be held at:
IAT Congress on Tuesday 21st March 2017 at 6pm
For the following purposes:
1. To consider the minutes of the thirtieth Annual General Meeting held
on Tuesday 8th March 2016 (as published in full on the Members’
section of the IAT website and in abridged form in the Bulletin Volume
52 No 6).
2. To receive and consider the Company’s annual accounts for the year
ended 31 December 2016 together with the Annual Report and the
Auditors’ report.
3. To appoint Auditors of the Institute.
4. To review the Council’s objectives for 2016.
5. To elect members of the Council who are proposed for re-election by
rotation under the terms of the Articles of Association and any such
new members to fill existing vacancies.
6. To elect a President and Vice-Presidents for the ensuing year.
7. To consider the election of Life and Honorary Members of the
Institute.
8. Any other business.
Dated: November 2016
Ken Applebee (Chair of Council)
Linda Horan (Honorary Secretary)
THE AGM IS OPEN TO ALL
Voting Rights are restricted to voting members only
Bulletin
16
November 2016
Laboratory Animal Science and Technology Higher Education courses
The Institute of Animal Technology (IAT) awards three Higher Education (HE)
qualifications, which can lead to IAT Fellowship and can be used towards a full
B.Sc. or higher degrees.
1
The HE programme is awarded by the IAT but delivered through the College of
Laboratory Animal Science & Technology (CLAST).
CLAST courses will:
G develop skills which are valued by employers
G enhance your personal development, preparing you for senior positions in
animal technology and related professions
G develop skills for studying in HE
G provide a route to access full graduate and post-graduate studies
Continuing Professional Development
Any of the units can be taken as CPD.
If you successfully complete the assessment you will be awarded an IAT CPD
Certificate detailing the completed unit. These certificates can be used to gain
exemption from those units if you decide to study for the full HE qualification
at a later date.
Each of the units are designed to develop specific skills and knowledge which
will be useful in your work and help with your career progression.
Current and previous students have used these units to:
G develop their management skills in preparation for promotion
G to enhance skills and help them in their current roles
G give them access to further specialist HE qualifications
G update their knowledge in specialist areas such as gene manipulation,
toxicology and others
1
Please note entry on to qualifications awarded by University of Middlesex, are subject
to their entry requirements at the time of enrolment.
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G develop a better understanding of current animal technology practices such
as health screening and immunology
G to gain the skills and knowledge required to manage major projects
G improve their knowledge of the law and animal welfare so they can
contribute more effectively to Animal Welfare Ethical Review processes and
the day to day care of laboratory animals.
For more information contact progdir@clast.org
Course timetable 2015-17
For enrolment forms contact admin@clast.org
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November 2016
AS-ET Annual Lecture
If you want to hear a leading world expert talk about one of the most important
biomedical subjects, come to the repeat of the AS-ET 2016 Annual Lecture on
30th November 2016:
Editing the genomes of animals and humans: where to draw
the line?
Presented by
Professor Robin Lovell Badge FRS
At
The Dalton Room, University of Manchester Innovation Centre,
Manchester at 6pm on 30th November 2016.
The lecture will be followed by a wine reception. Tickets cost £25 and can be
booked by going to the Events page of the AS-ET website (www.as-et.org.uk
) and
following the link to our PayPal account.
Co-Sponsors of the Manchester Lecture are:
James Bussell’s Great North Run
Congratulations to James who completed the Great North Run
in 2hr 2 mins and followed that with completing the Bristol Half
Marathon in less than 2 hrs. James has raised over £800 for
AS-ET and that figure is rising. You can still donate by going to
James’s Just Giving page:
https://www.justgiving.com/fundraising/James-Bussell1
AS-ET would like to thank all those who supported James and
especially James himself for supporting AS-ET.
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November 2016
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AS-ET is a charity to advance education and promote excellence in the care and
welfare of animals used in science.
Sponsors of AS-ET are listed below and to find out more please visit the website
www.as-et.org.uk
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November 2016
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New video tutorial on mouse
handling methods
A
new video tutorial, launched by the NC3Rs, shows technical staff and
researchers how to handle mice using non-aversive methods:
www.nc3rs.org.uk/mouse-handling-tutorial
The tutorial is based on research by Professor Jane Hurst and Dr Kelly Gouveia
at the University of Liverpool, funded by the NC3Rs and BBSRC.
1,2
The aim is to
promote widespread uptake of refined methods of handling laboratory mice
by providing practical advice and tackling common misconceptions about the
improved techniques.
Mice are the most common animal used in biomedical research but until
recently little was known about how best to approach and handle them from
the animal’s perspective. Yet handling is an important part of everyday
husbandry and precedes many experimental procedures. Depending on the
method used, handling can cause mice stress and influence their behaviour and
physiology, and so it can be a potential source of (unexplained) variability
within and between studies.
The tutorial first compares different methods of handling mice. The most
popular method currently used to handle mice is to pick them up by the base
of the tail. It is considered fast and allows for easy inspection of the animal but
Practicalities: cup
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November 2016
29
has no scientific validation and has been shown to cause anxiety in mice. The
tutorial then demonstrates the ‘mouse-friendly’ alternatives of tunnel handling
and cup handling, showing in a visual way why these alternatives are
preferable, as they improve response to handling and reduce anxiety and
stress.
Importantly, the tutorial goes beyond summarising the discoveries from
previous research and focuses on the practical side of things. Short videos
explain, in a clear, visual way, practicalities such as how to hold and manipulate
the tunnel correctly, how to habituate the animals to cupping and how to
incorporate these refined methods into routine husbandry and experimental
procedures. The resource addresses common misconceptions, for example by
showing that time taken for handling by the alternative methods is
comparable to the traditional approach.
Widespread use of the tutorial has the potential to significantly improve
animal welfare and the reliability of mouse studies.
Professor Hurst said: “We’ve been promoting tunnel and cup handling
methods for some time, including working directly with laboratories in industry
and academia. We’ve noticed staff trialling the refined methods for the first
time don’t always use them correctly, which is setting them up to fail holding
the tunnel in the wrong position in the home cage, for example, or chasing the
mice with the tunnel. Used properly, tunnel and cup handling take no longer
than tail handling and are practical even with jumpy strains.”
How practical are these methods?
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November 2016
Dr Mark Prescott, NC3Rs said: “The NC3Rs is asking staff in all laboratories
handling mice to watch the video tutorial and try again with the tunnel or cup
handling methods. The benefits of these methods for mouse welfare are clear,
and the evidence for them improving test responses is growing. So unless you
specifically want to induce anxiety in your mice for a research purpose, then
you really ought to be moving away from tail handling methods.”
References
1
Hurst J.L., West R.S. (2010). Taming anxiety in laboratory mice. Nature Methods.
Oct;7(10): 825-6.
2
Gouveia K., Hurst J.L. (2013). Reducing Mouse Anxiety during Handling: Effect of
Experience with Handling Tunnels. PLoS ONE 8(6): e66401.
Reproduced from NC3Rs
Council Election
Council Election
2017
2017
This is the final notice to apply if you are
thinking about joining Council in 2017. All
nomination forms must be submitted by
Wednesday 30th November via the contact
details in the announcement.
The IAT is run by our members for our
members.
Linda Horan
Honorary Secretary
Visit our website www.iat.org.uk f or further information
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November 2016
33
Cambridge Branch Paint Balling 2016
T
he afternoon of Saturday 8th October
2016 saw the Cambridge Branch hold its
second visit to Apocalypse Paintball. This time
there were 11 keen to ‘paint’ (and get
‘painted’!) and the weather was looking
moody and feeling chilly. However, with
smiles of anticipation the rain stayed away
and spirits were lifted when the games
began.
Despite the less than perfect weather, the venue got busy with a collection of
participants all wearing the combat overalls (one group added a ‘Mankini’ to
the outfit?!) and a protective face mask. A jovial safety brief was provided by
the Apocalypse marshal before the first game commenced. This year, it
included how to use a smoke grenade which got some players very excited!
It soon became clear that all participants, approximately 50 in total, were to
play together. Players were split into two teams based on the colour of the
paintball hopper they had been provided; black or clear.
There was a total of 5 games played (Capture the
Flag, Tyre Fortress, Defend the Village, Attack the
Village and Single Flag) each lasting approximately
10 minutes with a rest break between each.
Surprisingly, this is long enough to enjoy each game
given the intensity and ‘kill (pain/t) rate’
experienced.
The game arenas were again lively and fun,
providing plenty of opportunity to shoot and be
shot at with a range of features for defence against
the paintballs whizzing by. With adrenaline
pumping, no mask could hide the eyes of those
experiencing the mix of fear and excitement!
There were 400 paintballs included this year. Survival
time, ambitious shooting and a lot of luck dictated
how long these lasted. Most players eked out their
supply but some invested in smoke grenades in
order to try to gain advantage.
In the end, the ‘clear hopper’ team were the most
successful for the afternoon but everyone had a
great time and were ‘winners’ on the day. Despite
the injuries inflicted; minor pain, bruises and the
mess of the paintballs, there remained smiles all
around.
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Another big thank you to Allentown for kindly sponsoring this second
paintballing event and to Nathan Hill, Sales Director, for playing along with us
again!
Sam Jameson
Branch Reporter
RSPCA survey on severe suffering
resources
In 2015, the RSPCA Research Animals Department
(in conjunction with LASA, LAVA and
IAT) launched a new website
containing information and resources
aimed at helping people avoid or
reduce severe suffering in laboratory
animals. We are now seeking further
feedback from stakeholders both on
this website and on our other
activities related to the topic.
Please take a few minutes to complete the short
survey form, which can be found here:
https://goo.gl/forms/v3hj48nICazceA4J2
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November 2016
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Oxford Branch Day at the Races (continued)
O
n Saturday July 23rd the Oxford IAT branch made a return visit to Ascot for
the King George V1 and Queen Elizabeth race day. It was a coincidence
with the name of this meeting that on the previous evening we had gathered
in Oxford for the abdication of our Chair, Carol Williams. Carol is leaving her
position in Oxford to move to North Wales.
After a quick game of musical chairs we managed to fill the committee
positions without too much difficulty. Adrian Woodhouse will move from the
secretary’s position to become the Chair and his vacant post will in turn be
taken by April Shipton. It was then time to make our way into Oxford for a
leaving meal to celebrate the 6 years that Carol has been the Chair. The
Committee would like to thank Carol for all her efforts and wish her well. We
hope we will see her in some form within the industry in the future.
Now back to the day’s racing. After collecting our tickets we all made our way
into the racecourse for the obligatory group photo. We found a mural
depicting the day’s race meeting that looked suitable for the background.
Unfortunately, I was unaware as I had my back pressed onto the mural that
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November 2016
race goers had been invited to use
crayons to colour in the picture. As a
result of this I walked round for the
remainder of the day with my back
looking like part of Joseph’s Amazing
Technicolour Dream Coat.
I believe most of the group had some
success with their bets during the day
which made it even more enjoyable.
Having some interest in horse racing I
was asked for any advice on form. One
tip is Dusty Carpet, who will take one
hell of a beating!
The day went very fast and it was not long before we were all heading off
home.
I would like to thank our main sponsor for the day Agenda, for their generous
donation which provided discounted tickets. Thanks, also goes to IDEXX for
proving a liquid refreshment break during what was a very hot day.
In conclusion a very enjoyable day out with friends for what I am sure is
becoming an annual summer event.
John Bowler
Branch Reporter
APOLOGY
Somehow I managed to insert last year’s
report with this year’s pictures and publish it
in October’s issue. I did think that Ross’
emerald green jacket rang some bells but…
I can only think it was yet another senior
moment and would like to apologise to all
those involved with the Oxford branch.
Editor
Bulletin
November 2016
43
DIARY Dates
22-24 November
LASA Annual Conference
Details from info@lasa.co.uk
30 November
ABTA extended closing
date
Details from
admin@iat.org.uk
See pages 12 and 13
30 November
AS-ET Special Lecture
Manchester
Details from
contact@as-et.org.uk
See page 14
30 November
Closing date for Council
Nominations
See pages 30 and 31
8 December
RSPCA Lay Members’
Forum
London
Details from:
research.animals@rspca.org.uk
9 December
Animals Science Meeting
2016
London
Details from:
asg@rsb.org.uk
15 December
Final Posters Oral
Submissions at Congress
2017
See pages 10 and 11
18 December
Early Bird cut off date for
Congress registrations
See page 11
2017
27 January
Closing date for Congress
2017 Posters
See pages 10 and 11
Cover photo: Antelope Malcolm Gamble