VMRD Biologics Testing Services Catalog 2024 : simplebooklet.com

Testing ServicesVirus Testing ............................................................3Sterility Testing .......................................................11Mycoplasma Testing ............................................13Molecular (PCR) .....................................................15Specialized Testing ..............................................17Products and Reagents ......................................18Sample Submission Process ..............................19

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On behalf of the whole VMRD team, thank you for your business! VMRD was founded with the goal of bringing better tests to you, our customers. Better tests yield better diagnoses, better relationships, better outcomes, better bottom lines, and better days. Our products and services team members strive every day to accomplish the better test goal. If we ever fail to achieve this goal, please do not hesitate to contact any member of the VMRD team, including me personally, so that we can make it right. That is the way we would want to be treated, and we will do our best to treat you that way. May you have only good days at the bench!Soli Deo gloria,Ethan Adams, CEO

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INTEGRITY In keeping with our company values of doing unto others as we would have them do unto us, we test your samples with the same care and diligence that we apply to our own samples. You want results quickly, but you also need to make sure that your product is free of adventitious agents and that the regulatory testing requirements have been satisﬁed. We keep both things in mind as we work with your sample and are constantly improving our processes.QUALITY VMRD testing is performed by highly qualiﬁed staﬀ to current Good Laboratory Practices (cGLP, 21CFR §58). We are continually investing in our quality management system that encompasses all aspects of our testing services. We are currently registered to ISO 9001:2015. Our laboratory currently operates in a USDA licensed facility. Our assays are internally validated or veriﬁed to provide the best possible sensitivity for the detection of adventitious agents. We welcome customer audits and look forward to hosting you and/or your company’s representative. EXPERIENCE We have more than 34 years of business experience and over 50 years of combined laboratory testing experience. We have optimized and reﬁned our methods, bench records, and reporting for maximum accuracy and acceptability to regulatory oﬃcials. We have accessioned over 6500 test articles, published more than 13,000 ﬁnal reports and worked with over 90 customers within the last 6 years. This experience allows us to oﬀer a wide range of regulatory and custom testing suited to each customer’s needs. CONVENIENCE Our assay oﬀerings are geared toward providing one-stop testing, saving you time and money. Sample submission, test selection, and result reporting are facilitated through a secure online portal providing easy, self-service access to current and previous test results. Our dedicated sales staﬀ are always available to assist with any inquiries and our Study Directors are happy to consult on any technical matters. 509.334.5815 | www.vmrd.com/services2

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509.334.5815 | www.vmrd.com/services4VMRD Testing Services oﬀers several validated or veriﬁied assays to evaluate a wide range of test articles for extraneous viruses as speciﬁed in various regulations and/or guidance documents including:Contact us today to ﬁnd out more!BOVINE RAW MATERIAL TESTINGCATALOG # ASSAY DESCRIPTION | REGULATION SATISFIED VOLUME REQUIRED ASSAY LENGTH9C-AOP-BOV/VERO* Bovine Virus Assay | 9 CFR 113.53(c) 50 mL or 2 grams 22 daysM9C-AOP-BOV Modiﬁed Bovine Virus Assay (virus speciﬁc) 30 mL or 1 gram 22 daysM9C-AOP-BOV-BPyV BPyV Virus Assay 50 mL 22 daysM9C (or MEM)-AOP-MON-ROTA Rotavirus Assay using MA-104 cells 50 mL or 2 grams 22 daysEM-AOP-BOV/VERO† Bovine Virus Assay | EP 5.2.5; CVMP 4.3.3.1,2; CHMP 7.3.1,2,3 100 mL 22 daysMEM-AOP-BOV Modiﬁed Bovine Virus Assay (virus speciﬁc) 50 mL 22 daysSN-AOP-BOV Serum Neutralization, Bovine Viruses | CVMP 4.3.3.3; CHMP 7.3.4 5 mL 7 daysVR-AOP-BOV Virus Reduction - Serum Neutralization Assay 5 mL 7 daysALPHA-AOP-BOV Serum Neutralization, Bovine Virus | CVMP 4.3.3.3; CHMP 7.3.4 5 mL 7 daysQUANT-AOP-BOV Sample Ultracentrifugation & BVD quantiﬁcation CVMP 4.3.3.2, CHMP 7.3.3 35 mL 7 daysLT-AOP-BOV (BVD, HAD/Giemsa) CPE, HAD Virus Assay and BVD by FA 30 mL or 2 grams 22 daysCell-Viability Test for determination of the viability of cells after TA exposure 30 mL ≥21 daysRID-BOV-IGG Bovine IgG identiﬁcation by RID of Bovine Origin Product Call/Email 2-3 daysAOP-GPA-5D Growth Promotion Assay - Two Cell Lines/5 Day Method 25 mL 5 daysTEST ARTICLE TYPE: ANIMAL ORIGIN PRODUCT• USDA-APHIS 9 CFR• CVMP | CHMP • European Medicines Agency (EMA) • European Pharmacopeia (EP) monographs• United States Pharmacopeia (USP) monographsAdditionally (to cGLP standards)• Custom Validation Projects • Non-clinical laboratory studies• Other in vitro virology custom assays • Master Seed Bank (cells and/or virus) production and accompanying regulatory testing

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Veterinary Medical Research & Development | services@vmrd.com5BOVINE RAW MATERIAL TESTING CONTINUEDCATALOG # ASSAY DESCRIPTION | REGULATION SATISFIED VOLUME REQUIRED ASSAY LENGTH9C-CL-BOV-PT1 and/or PT2‡ Bovine Virus Assay of Bovine Cell Line | 9 CFR 113.52(e)&(f) Call or Email 22 days PT1 22 days PT2M9C-CL-BOV Modiﬁed Bovine Virus Assay of Bovine Cell Line Call or Email 22 daysM9C (or MEM)-CL-MON-ROTA Rotavirus Assay of Cell Line, MA-104 cells Call or Email 22 daysM9C (or MEM)-CL-MON-PRRS PRRS Virus Assay of Cell Line, MARC cells Call or Email 22 daysEM-CL-BOV-PT1 and/or PT2‡ Virus Assay of Bovine Cell Line | EP 5.2.4 — Viruses to be speciﬁed by customer Call or Email 22 days PT1 22 days PT29C-MSV-BOV Bovine Virus Assay of Master Seed Virus | 9 CFR 113.55 2 x 1 mL 22 daysM9C-MSV-BOV Modiﬁed Bovine Virus Assay of Master Seed Virus 2 x 1 mL 22 daysEM-MSV-BOV Bovine Virus Assay of MSV | EP 04/2013:0062, 2-1-3-2-6 Call or Email 22 daysVT-MSV-BOV Virus Titration of Virus Stock to Determine TCID50/mL 2 vials 7 daysTEST ARTICLE TYPE: CELL LINE**TEST ARTICLE TYPE: MASTER SEED VIRUS****Viruses tested by FA include: BTV, BAV3, BAV5, BPV, BRSV, BVDV, REO, RAB. Non-speciﬁc viral testing includes: Cytopathic Eﬀect (Giemsa) and Hemadsorption.†Includes all 9 CFR Bovine viruses with the addition of BLV and VSV, as well as weekly CPE and Hemadsorption checks.Optional virus tests: VSV, BLV, IBR/BHV-1, PI-3, BCV, PRV‡Part 1 of cell line testing = growing the original cell line and testing for species appropriate adventitious agents‡Part 2 of cell line testing = testing cell lysates of grown cell line (VMRD or by company) on intended target specie and species of origin**Cell lines must have an accompanying growth protocol before submission. Contact Account Manager for Cell Line intake Form.***MSV’s must have an accompanying neutralizing anti-sera and neutralization protocol. Contact Account Manager for MSV intake form. All 9 CFR assays (9C-), including modiﬁed 9 CFR assays (M9C-), employ the methodologies outlined in 9 CFR 113.46 and 113.47.All EM assays (EM-), including modiﬁed EM assays (MEM-) employ the methodologies outline in EP 5.2.5 as well as 9 CFR 113.46 and 113.47.Please allow 3-5 business days for ﬁnal report review and release. This includes ﬁnal review by the assigned study director and Quality Assurance audit of the bench records.

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509.334.5815 | www.vmrd.com/services69C-CL-POR-PT1 and/or PT2‡ Porcine Virus Assay of Porcine Cell Line | 9 CFR 113.52(e)&(f) Call or Email 22 days PT1 22 days PT2M9C-CL-POR Modiﬁed Porcine Virus Assay of Porcine Cell Line Call or Email 22 daysEM-CL-POR-PT1 and/or PT2‡ Virus Assay of Porcine Cell Line | EP 5.2.4 — Viruses to be speciﬁed by customer Call or Email 22 daysM9C (or MEM)-CL-MON-ROTA Rotavirus Assay of Cell Line using MA-104 cells Call or Email 22 daysM9C (or MEM)-CL-MON-PRRS PRRS Virus Assay of Cell Line using MARC cells Call or Email 22 days9C-MSV-POR Porcine Virus Assay of Master Seed Virus | 9 CFR 113.55 2 x 1 mL 22 daysM9C-MSV-POR Porcine Virus Assay of MSV (virus speciﬁc) 2 x 1 mL 22 daysEM-MSV-POR Porcine Virus Assay of MSV | EP 04/2013:0062, 2-1-3-2-6 2 x 1 mL 22 daysVT-MSV-POR Virus Titration of Virus Stock to Determine TCID50/mL 2 vials 7 daysTEST ARTICLE TYPE: CELL LINE**TEST ARTICLE TYPE: MASTER SEED VIRUS****Viruses tested by FA for 9 CFR and EM include: BVD, REO, RAB, PAV, PPV, TGE, PHEV. Non-speciﬁc viral testing includes: Cytopathic Eﬀect (Giemsa) and Hemadsorption.Optional virus tests: PCV1, PCV2, PCMV, PIV/SIV, PRCV, PRV, VSV, SVA**, ***, ‡See page 5PORCINE RAW MATERIAL TESTINGCATALOG # ASSAY DESCRIPTION | REGULATION SATISFIED VOLUME REQUIRED ASSAY LENGTH9C-AOP-POR/VERO* Porcine Virus Assay | 9 CFR 113.53c 50 mL or 2 grams 22 daysM9C-AOP-POR Modiﬁed Porcine Virus Assay (virus speciﬁc) 25 mL or 1 gram 22 days9C-PT-POR PPV Virus Assay of Porcine Trypsin | 9 CFR 113.53d 5 grams 28 daysM9C (or MEM)-AOP-MON-ROTA Rotavirus Assay using MA-104 cells 50 mL or 2 grams 22 daysM9C (or MEM)-AOP-MON-PRRS PRRS Virus Assay using MARC cells 50 mL or 2 grams 22 daysEM-AOP-POR/VERO Porcine Virus Assay | EP 5.2.5 50 mL or 2 grams 22 daysMEM-AOP-POR Modiﬁed Porcine Virus Assay (virus speciﬁc) 50 mL or 2 grams 22 daysSN-AOP-POR Serum Neutralization Assay, Porcine Viruses 5 mL 7 daysALPHA-AOP-POR Serum Neutralization, Porcine Viruses 5 mL 7 daysQUANT-AOP-POR Ultracentrifugation of Porcine Product & PPV Quantiﬁcation 25 mL or 1 gram 7 daysLT-AOP-POR (BVD, HAD/Geimsa) CPE, HAD Virus Assay and BVD by FA 30 mL or 2 grams 22 daysTEST ARTICLE TYPE: ANIMAL ORIGIN PRODUCT

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Veterinary Medical Research & Development | services@vmrd.com79C-CL-EQU-PT1 and/or PT2‡ Equine Virus Assay of Equine Cell Line | 9 CFR 113.52(e)&(f) Call or Email 22 days PT1 22 days PT2M9C-CL-EQU Modiﬁed Equine Virus Assay of Equine Cell Line Call or Email 22 daysEM-CL-EQU-PT1 and/or PT2‡ Virus Assay of Equine Cell Line | EP 5.2.4 — Viruses to be speciﬁed by customer Call or Email 22 daysM9C (or MEM)-CL-MON-ROTA Rotavirus Assay of Cell Line using MA-104 cells Call or Email 22 days9C-MSV-EQU Equine Virus Assay of Master Seed Virus | 9 CFR 113.55 2 x 1 mL 22 daysM9C-MSV-EQU Modiﬁed Equine Virus Assay of Master Seed Virus 2 x 1 mL 22 daysVT-MSV-EQU Virus Titration of Virus Stock to Determine TCID50/mL 2 vials 22 daysTEST ARTICLE TYPE: CELL LINE**TEST ARTICLE TYPE: MASTER SEED VIRUS****Viruses tested by FA include: BVD, REO, RAB, EHV, EAV. Non-speciﬁc viral testing includes: Cytopathic Eﬀect (Giemsa) and Hemadsorption.Optional virus tests: NA**, ***, ‡See page 5EQUINE RAW MATERIAL TESTINGCATALOG # ASSAY DESCRIPTION | REGULATION SATISFIED VOLUME REQUIRED ASSAY LENGTH9C-AOP-EQU/VERO* Equine Virus Assay | 9 CFR 113.53(c) 50 mL or 2 grams 22 daysM9C-AOP-EQU Modiﬁed Equine Virus Assay (virus speciﬁc) 25 mL or 1 gram 22 daysM9C (or MEM)-AOP-MON-ROTA Rotavirus Assay using MA-104 cells 50 mL or 2 grams 22 daysEM-AOP-EQU/VERO Equine Virus Assay | EP 5.2.5 50 mL or 2 grams 22 daysMEM-AOP-EQU Modiﬁed Equine Virus Assay (virus speciﬁc) 50 mL or 2 grams 22 daysSN-AOP-EQU Serum Neutralization Assay, Equine Viruses 5 mL 7 daysLT-AOP-EQU (BVD, HAD/Giemsa) CPE, HAD Virus Assay and BVD by FA 30 mL or 2 grams 22 daysTEST ARTICLE TYPE: ANIMAL ORIGIN PRODUCT

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509.334.5815 | www.vmrd.com/services89C-CL-CAN-PT1 and/or PT2‡ Canine Virus Assay of Canine Cell Line | 9 CFR 113.52(e)&(f) Call or Email 22 days PT1 22 days PT2M9C-CL-CAN Modiﬁed Canine Virus Assay of Equine Cell Line Call or Email 22 daysEM-CL-CAN-PT1 and/or PT2‡ Virus Assay of Canine Cell Line | EP 5.2.4 — Viruses to be speciﬁed by customer Call or Email 22 daysM9C (or MEM)-CL-MON-ROTA Rotavirus Assay of Cell Line using MA-104 cells Call or Email 22 days9C-MSV-CAN Canine Virus Assay of Master Seed Virus | 9 CFR 113.55 2 x 1 mL 22 daysM9C-MSV-CAN Modiﬁed Canine Virus Assay of Master Seed Virus 2 x 1 mL 22 daysVT-MSV-CAN Virus Titration of Virus Stock to Determine TCID50/mL 2 vials 22 daysTEST ARTICLE TYPE: CELL LINE**TEST ARTICLE TYPE: MASTER SEED VIRUS****Viruses tested by FA include: BVD, REO, RAB, CCV, CDV, CPV. Non-speciﬁc viral testing includes: Cytopathic Eﬀect (Giemsa) and Hemadsorption.Option virus tests: CHV**, ***, ‡See page 5CANINE RAW MATERIAL TESTINGCATALOG # ASSAY DESCRIPTION | REGULATION SATISFIED VOLUME REQUIRED ASSAY LENGTH9C-AOP-CAN/VERO* Canine Virus Assay | 9 CFR 113.53(c) 50 mL or 2 grams 22 daysM9C-AOP-CAN Modiﬁed Canine Virus Assay (virus speciﬁc) 50 mL or 2 grams 22 daysM9C (or MEM)-AOP-MON-ROTA Rotavirus Assay using MA-104 cells 50 mL or 2 grams 22 daysEM-AOP-CAN Canine Virus Assay | EP 5.2.5 50 mL or 2 grams 22 daysMEM-AOP-CAN Modiﬁed Canine Virus Assay (virus speciﬁc) 50 mL or 2 grams 22 daysSN-AOP-CAN Serum Neutralization Assay, Canine Viruses 5 mL 7 daysLT-AOP-CAN (BVD, HAD/Giemsa) CPE, HAD Virus Assay and BVD by FA 30 mL or 2 grams 22 daysTEST ARTICLE TYPE: ANIMAL ORIGIN PRODUCT

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Veterinary Medical Research & Development | services@vmrd.com99C-CL-FEL-PT1 and/or PT2 Feline Virus Assay of Feline Cell Line | 9 CFR 113.52(e)&(f) Call or Email 22 daysM9C-CL-FEL Modiﬁed Feline Virus Assay of Feline Cell Line Call or Email 22 daysEM-CL-FEL-PT1 and/or PT2‡ Virus Assay of Feline Cell Line | EP 5.2.4 — Viruses to be speciﬁed by customer Call or Email 22 daysM9C (or MEM)-CL-MON-ROTA Rotavirus Assay of Cell Line using MA-104 cells Call or Email 22 days9C-MSV-FEL Feline Virus Assay of Master Seed Virus | 9 CFR 113.55 2 x 1 mL 22 daysM9C-MSV-FEL Modiﬁed Feline Virus Assay of Master Seed Virus 2 x 1 mL 22 daysVT-MSV-FEL Virus Titration of Virus Stock to Determine TCID50/mL 2 vial 7 daysTEST ARTICLE TYPE: CELL LINE**TEST ARTICLE TYPE: MASTER SEED VIRUS****Viruses tested by FA include: BVD, REO, RAB, FIP, FPL. Non-speciﬁc viral testing includes: Cypathic Eﬀect (Giemsa), and HemadsorptionOption virus tests: FCV, FHV, FVR, FeLV**, ***, ‡See page 5FELINE RAW MATERIAL TESTINGCATALOG # ASSAY DESCRIPTION | REGULATION SATISFIED VOLUME REQUIRED ASSAY LENGTH9C-AOP-FEL/VERO* Feline Virus Assay | 9 CFR 113.53(c) 50 mL or 2 grams 22 daysM9C-AOP-FEL Modiﬁed Feline Virus Assay (virus speciﬁc) 50 mL or 2 grams 22 daysM9C (or MEM)-AOP-MON-ROTA Rotavirus Assay using MA-104 cells 50 mL or 2 grams 22 daysEM-AOP-FEL Felne Virus Assay | EP 5.2.5 50 mL or 2 grams 22 daysMEM-AOP-FEL Modiﬁed Feline Virus Assay (virus speciﬁc) 50 mL or 2 grams 22 daysSN-AOP-FEL Serum Neutralization Assay, Feline Viruses 5 mL 7 daysLT-AOP-FEL (BVD, HAD/Giemsa) CPE, HAD Virus Assay and BVD by FA 30 mL or 2 grams 22 daysTEST ARTICLE TYPE: ANIMAL ORIGIN PRODUCT

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509.334.5815 | www.vmrd.com/services109C (or M9C)-CL-CAP-PT1 and/or PT2‡ Caprine Virus Assay of Bovine Cell Line | 9 CFR 113.52(e)&(f) Call or Email 22 days9C (or M9C)-CL-LAP-PT1 and/or PT2‡ Lapine Virus Assay of Bovine Cell Line | 9 CFR 113.52(e)&(f) Call or Email 22 days9C (or M9C)-CL-HAM-PT1 and/or PT2‡ Hamster Virus Assay of Bovine Cell Line | 9 CFR 113.52(e)&(f) Call or Email 22 days9C (or M9C)-CL-OVI-PT1 and/or PT2‡ Ovine Virus Assay of Bovine Cell Line | 9 CFR 113.52(e)&(f) Call or Email 22 days9C (or M9C)-CL-MUR-PT1 and/or PT2‡ Murine Virus Assay of Bovine Cell Line | 9 CFR 113.52(e)&(f) Call or Email 22 days9C (or M9C)-CL-MUS-PT1 and/or PT2‡ Mustelid Virus Assay of Bovine Cell Line | 9 CFR 113.52(e)&(f) Call or Email 22 days9C (or M9C)-MSV-CAP Caprine Virus Assay of Master Seed Virus | 9 CFR 113.55 2 x 1 mL 22 daysVT-MSV-CAP Virus Titration of Virus Stock to Determine TCID50/mL 2 vials 7 days9C (or M9C)-MSV-LAP Lapine Virus Assay of Master Seed Virus | 9 CFR 113.55 2 x 1 mL 22 daysVT-MSV-LAP Virus Titration of Virus Stock to Determine TCID50/mL 2 vials 7 days9C (or M9C)-MSV-HAM Hamster Virus Assay of Master Seed Virus | 9 CFR 113.55 2 x 1 mL 22 daysVT-MSV-HAM Virus Titration of Virus Stock to Determine TCID50/mL 2 vials 7 days9C (or M9C)-MSV-MUR Murine Virus Assay of Master Seed Virus | 9 CFR 113.55 2 x 1 mL 22 daysVT-MSV-MUR Virus Titration of Virus Stock to Determine TCID50/mL 2 vials 7 days9C (or M9C)-MSV-MUS Mustelid Virus Assay of Master Seed Virus | 9 CFR 113.55 2 x 1 mL 22 daysVT-MSV-MUS Virus Titration of Virus Stock to Determine TCID50/mL 2 vials 7 daysTEST ARTICLE TYPE: CELL LINE**TEST ARTICLE TYPE: MASTER SEED VIRUS*****, ***See page 5MULTIPLE SPECIES RAW MATERIAL TESTINGCATALOG # ASSAY DESCRIPTION | REGULATION SATISFIED VOLUME REQUIRED ASSAY LENGTH9C-AOP-CAP/VERO Caprine Virus Assay | 9 CFR 113.53(c) 50 mL or 2 grams 22 days9C-AOP-OVI/VERO Ovine Virus Assay | 9 CFR 113.53(c) 50 mL or 2 grams 22 days9C-AOP-LAP/VERO Lapine Virus Assay | 9 CFR 113.53(c) 50 mL or 2 grams 22 days9C-AOP-HAM/VERO Hamster Virus Assay | 9 CFR 113.53(c) 50 mL or 2 grams 22 days9C-AOP-MUR/VERO Murine Virus Assay | 9 CFR 113.53(c) 50 mL or 2 grams 22 days9C-AOP-MUS/VERO Mustelid Virus Assay | 9 CFR 113.53(c) 50 mL or 2 grams 22 daysTEST ARTICLE TYPE: ANIMAL ORIGIN PRODUCT

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509.334.5815 | www.vmrd.com/services12VMRD Testing Services sterility assays include assessment of bacteriostasis/fungistasis of each test article in order to validate the sterility result and conﬁrm that there are no antimicrobial properties within the test article. Our testing paradigm therefore encapsulates 9 CFR 113.25(d) in addition to 9 CFR 113.26.STERILITY TESTINGCATALOG # ASSAY DESCRIPTION | REGULATION SATISFIED VOLUME REQUIRED ASSAY LENGTH9C-B&F Sterility Assay of Animal Origin Product | 9 CFR 113.26 100 mL or 10 grams 14 days9C-B&F-MSV Sterility Assay of Virus Samples | 9 CFR 113.27(c) 5 x 1 mL 14 days9C-B&F-CL Sterility Assay of Cell Lines | 9 CFR 113.52(d) 25 x 1 mL 14 days9C-B&F-BAC Sterility Assay of Master Seed Bacteria | 9 CFR 113.27(d) 5 x 1 mL 14 daysBACTERIA & FUNGI TESTING

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VMRD Testing Services offers mycoplasma assays to satisfy various regulations, including:• USDA-APHIS 9 CFR (9 CFR 113.52c,113.53a using methods described in 113.28)• European Pharmacopeia (EP), European Medicinal Agency (EMA) (EP 2.6.7, EMA) • United States Pharmacopeia (USP <63>)Each assay has been validated or verified to provide the best possible sensitivity for the detection of Mollicutes in your test article. The EP mycoplasma testing includes an inhibition assay (substrate qualification) to evaluate the test article for inhibition of mycoplasma growth as per EP 2.6.7 & USP <63> regulations and has been validated with seven different Mollicutes strains.* 14509.334.5815 | www.vmrd.com/services9 CFR 113.28 EP 2.6.7 USP <63>LARGE VOLUME BARILE METHODVeterinary product for sale in USAVeterinary product for sale in EuropeSerum for use in production of human & veterinary medicine for sale in EuropeTrypsin for use in production of human medicine for sale in EuropeViral veterinary vaccines for sale in EuropeSerum, media, or other byproducts with a non-speciﬁed useApproved by the International Serum Industry AssociationVMRD Catalog Number(s)9C-MYEPUSP-MY-DIREPUSP-MY-INDEPUSP-MY-IN-DIR/IND (Substrate Qualiﬁcation)EPUSP-MY-DIR-17025EPUSP-MY-IND-17025(ISO 17025:2017 accredited assays)LVB-MY-B&ALVB-MY-IND*In addition, we oﬀer a fully validated Large Volume method that achieves a level of sensitivity unattainable by the regulated methods. Ask us today which mycoplasma detection method is the best ﬁt for your needs.

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16509.334.5815 | www.vmrd.com/servicesASFvWe oﬀer a US-based solution for your ASFv testing needs. Following the Ministry of Agriculture and Rural Aﬀairs (MARA) requirements of the People’s Republic of China, we have developed an ASFv PCR test that has been veriﬁed for veterinary biologics destined for export. This includes live vaccines, aqueous and non-aqueous adjuvant attenuated vaccines. This assay is currently available and adaptable to your product. Contact us today for your sample suitability testing needs for this assay.VMRD Catalog #: PCR-ASFBVDV Genotypes 1, 2, 3We oﬀer a fully validated Reverse Transcriptase PCR assay to CVB and ICH standards, in addition to our classical infectivity assay using cell culture with direct ﬂuorescent antibody detection technique(s).VMRD Catalog #: PCR-BVDKaryotypingWhen creating a master cell bank, it is important to have complete cell line characterization to 9 CFR 113.52. To provide complete testing for cell line characterization, we have partnered with a specialized lab to provide karyotyping. All samples that need karyology can be sent to VMRD directly and we will handle the rest!VMRD Catalog #: 9C-CL-KARDeep SequencingTo round out your cell line characterization we oﬀer speciation of cell lines through deep sequencing. Our partnering lab is local to our facility, and we are able to hand deliver your sample for deep sequencing, eliminating the chance for shipping errors. Contact us today for your speciation needs!VMRD Catalog #: 9C-NGS

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SPECIALIZED TESTINGAre you not finding what you looking for, but still need testing services? Our laboratory setup and structure allows us to offer custom testing to fit your needs. Some examples include, but are not limited to: • Master Cell and Master Seed Generation and Associated Regulatory Testing• Mycoplasma consultation• Validation Studies• Non-Clinical Laboratory Study Support• Viral Inactivation Studies• And much more!Contact us today to find out more!17Veterinary Medical Research & Development | services@vmrd.com

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PRODUCTS & REAGENTSThe VMRD portfolio is the most comprehensive in veterinary diagnostics and has a wide range of products that include USDA-licensed ELISA kits, immunofluorescence reagents, antibodies, and Coombs testing reagents. In an effort to better support our customer’s needs, we are expanding our portfolio to include point of care and nucleic acid extraction product lines. All of VMRD’s ELISA kits are USDA licensed and offer diagnostic tools for a variety of species including bovine, equine, caprine, and ovine.VMRD immunofluorescence reagents include slides, monoclonal antibodies, conjugates, and more. These products target both large and companion animal diseases. VMRD brings testing to the animal’s side with lateral flow test kits for horses and soon to come feline testing. Its compact reader size travels easily and its quantitative output provides real-time results of current disease status.18509.334.5815 | www.vmrd.com/services

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SAMPLE SUBMISSIONBUSINESS HOURS Monday - Friday, 7 am - 4 pm (Pacific Time Zone)ORDERING TESTING SERVICES PROCEDURES Contact our Testing Services Sales department at services@vmrd.com to get more information and a quote. After a quote has been generated this can be used as a reference for submitting samples for testing on our customer portal.CUSTOMER PORTAL VMRD Testing Services Customer Portal acts as a bridge between the submitting laboratory and our Laboratory Information Management System (LIMS). Our portal lets you submit samples for testing, and have secure 24-hour access to up-to-date testing information. In addition, final reports are available immediately after QA approval, which provides you with faster access to results. SAMPLE SUBMISSION & SHIPPING PROCEDURES Samples that are ready to be tested are submitted through our online portal. Using the provided quote you can select for the specific tests that correlate to each sample. For more information on our sample submission, please visit vmrd.com/biologics-testing-submission/After samples have been submitted through our online portal, the samples can be shipped to our Sample Submission Address (see page 20). The address and sample submission form are very important when shipping samples to our facility. For more information regarding sample packaging recommendations, please visit vmrd.com/biologics-testing-submission/19Veterinary Medical Research & Development | services@vmrd.com

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20509.334.5815 | www.vmrd.com/servicesSAMPLE SUBMISSION ADDRESS VMRD, Inc – Testing Services 425 NW Albion Dr. Suite 2 Pullman, WA 99163INVOICING PROCEDURES Billing Invoices for our services are emailed after the test has completed and the final report has been released. Default payment terms are Net 30 days, payable in U.S. Dollars. Please inquire to arrange payment by wire transfer. Payment may also be made by Visa, MasterCard, or American Express credit cards. Please specify payment by credit card when the order is placed. Do not use email to send credit card information. Invoice questions may be directed to our Customer Service Department at +1-509-334-5815 or 1-800-222-8673. Bank Wire Transfer Notification and payment instructions are available upon request.

VMRD Biologics Testing Services Catalog 2024

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