HIP Symposium 33 : simplebooklet.com

12:00-12:05 pm12:05-12:25 pm12:25-12:45 pm12:45-12:55 pm12:55-1:05 pm 1:05-1:15 pmWELCOME AND INTRODUCTIONSAPPROVED VACCINES AND VARIANTSVIRAL EPIDEMIOLOGIC PERSPECTIVEMANUFACTURING, DISTRIBUTION, ANDWORKFORCE PERSPECTIVEDIAGNOSTIC AND THERAPEUTIC PERSPECTIVEVACCINE SAFETY AND ADVERSE EVENTSBarton Haynes, MDFrederic M. Hanes Professor of Medicine Professor of Immunology and Global Health Director, Human Vaccine institute Duke University School of MedicineFred Sanfilippo MD, PhDDirector, Emory-Georgia Tech Healthcare Innovation ProgramProfessor of Pathology & Laboratory Medicine, Emory School of MedicineProfessor of Health Policy & Management, Rollins School of Public Health Kathryn Edwards, MDSarah H. Sell and Cornelius Vanderbilt Professor Division of Infectious DiseaseDepartment of Pediatrics Director Clinical Immunization Safety Assessment Program Vanderbilt University School of MedicineDavid Stephens, MDVice President for Research, Woodruff Health Sciences Center Chair and StephenW. Schwarzmann Distinguished Professor of Medicine Department of Medicine Emory University School of MedicineAnne Piantadosi, MD, PhDAssistant Professor Department of Pathology and Laboratory MedicineEmory University School of MedicineKrish Roy, PhDRobert A. Milton Chair Professor Director, NSF Engineering Research Center for Cell Manufacturing Technologies Director, Marcus Center for Therapeutic Cell Characterization and Manufacturing Director, Center for ImmunoEngineeringWallace H. Coulter Department of Biomedical Engineering At Emory and Georgia TechProgram1:15-1:30 pmQ&A SESSION

Page 3

Barton Haynes, MDHuman Vaccine InstituteDuke UniversityDr. Barton F. Haynes, M.D. is the Frederic M.Hanes Professor of Medicine and Immunology,and Director of the Human Vaccine Institute inthe Duke University School of Medicine. Priorto leading the Vaccine Institute at Duke, heserved as Chief of the Division ofRheumatology, Allergy and Clinical Immunologyand later as Chair of the Department ofMedicine. As Director of the Duke HumanVaccine Institute, he leads a team ofinvestigators working on vaccines for emerginginfections, including tuberculosis, pandemicinfluenza, emerging coronaviruses andHIV/AIDS. To work on the AIDS vaccineproblem, his group has been awarded twolarge consortium grants from the NIH, NIAIDknown as the Center for HIV/AIDS VaccineImmunology, and the Center for HIV/AIDSVaccine Immunology-Immunogen Discovery toconduct discovery science to speed HIVvaccine development. In July 2019, his teamreceived the third of NIH “CHAVI” awards tocomplete the HIV vaccine development work.Since the beginning of the COVID-19pandemic, Haynes and the DHVI Team hasbeen working non-stop to develop vaccines,rapid and inexpensive tests and therapeuticsto combat the pandemic. Since March, 2020,he has served as a member of the NIHAccelerating COVID-19 TherapeuticInterventions and Vaccines (ACTIV) committeeto advise on COVID-19 vaccine development,and served as the co-chair of the ACTIVsubcommittee on vaccine safety. Haynes is the winner of the AlexanderFleming Award from the Infectious DiseaseSociety of America and the Ralph SteinmanAward for Human Immunology Researchfrom the American Association ofImmunologists. He is a member of theNational Academy of Medicine, NationalAcademy of Inventors and the AmericanAcademy of Arts and Sciences.

Page 4

Kathryn Edwards, MDVanderbilt Vaccine Research Program Vanderbilt UniversityKathryn Edwards is a professor at theVanderbilt University School of Medicine. Sheholds the Sarah H. Sell Chair in Pediatrics,and is the director of the Vanderbilt VaccineResearch Program. Dr. Edwards received hermedical degree at the University of Iowa andcompleted her residency and fellowship atChildren's Memorial Hospital atNorthwestern University. Dr. Edwards' clinicalwork focuses on preventing and managinginfectious diseases in children. She has beeninvolved in many of the pivotal studies onvaccine effectiveness, safety and impactconducted over the last three decades. Shehas contributed to the formulation of vaccinepolicy for the U.S. and the evaluation of theimpact of various vaccine programs. Dr.Edwards has published more than 260articles on vaccines and pediatric infectiousdiseases, and is a fellow of the InfectiousDiseases Society of America and theAmerican Academy of Pediatrics. Dr. Edwardsis actively engaged in mentoring younginvestigators and received the MentorshipAward from the Infectious Disease Society ofAmerica in 2006. In 2007, she was therecipient of both the Pediatric AcademicSociety Plotkin Lectureship in Vaccinologyand the Infectious Disease Society of AmericaSmadel Award. She was elected into theInstitute of Medicine in 2008.

Page 5

David Stephens, MD Emory University School of MedicineEmory UniversityAs chair of the Department of Medicine,Stephens leads the department's tripartitemission to advance human health throughinnovation in research, education, andpatient care. As the vice president forresearch for the Woodruff Health SciencesCenter, he has focused on growth ofmultidisciplinary research across the WHSCand Emory University; development ofinnovative research initiatives; enhancementof research strategic themes andcollaborations at Emory and among local,national, and international partners; andresearch training and career development.Stephens’ laboratory is an internationalleader in efforts to define the molecular basisfor the virulence of bacterial meningitis andvaccines to prevent it, especially diseasecaused by Neisseria meningitidis andStreptococcus pneumoniae. He hascontributed to more than 330 publications ininfectious diseases, molecular pathogenesis,epidemiology, vaccinology and immunology.He has served as the site principalinvestigator for multiple NIH RO1 and otherfederal grants including the NIH-sponsoredSoutheastern Regional Center of Excellencefor Emerging Infections and Biodefense, theCDC-supported Southeastern Center forEmerging Biologic Threats, and the NIH-funded Exploratory Center forInterdisciplinary Research in Vaccinology.The infectious diseases programStephens helped develop hasgraduated more than 150 fellows, andhis laboratory has trained over 96infectious diseases fellows,postdoctoral fellows, medical studentsand undergraduates in bacterialpathogenesis. He serves as chief ofmedicine of Emory Healthcare androunded for 30 years in infectiousdiseases and medicine at GradyMemorial Hospital and the Atlanta VAMedical Center.

Page 6

Dr. Piantadosi earned an MD/PhD from theUniversity of Washington in 2011, studyingHIV-1 superinfection and within-hostevolution under the mentorship of Dr. JulieOverbaugh. She then completed clinicaltraining in Internal Medicine and InfectiousDisease at Massachusetts General Hospital.As a post-doctoral researcher in thelaboratory of Dr. Pardis Sabeti at the BroadInstitute, Dr. Piantadosi led a multidisciplinarytranslational research project to evaluateviral causes of encephalitis usingmetagenomic sequencing. In the fall of 2019,Dr. Piantadosi began as an AssistantProfessor in the Department of Pathology atEmory, with a joint appointment in theDepartment of Medicine, Division ofInfectious Diseases, where she continues tobe a practicing physician.Anne's research interest is the emergence,evolution, and pathogenesis of viruses ofclinical and public health importance, with aparticular interest in arboviruses and virusesthat cause central nervous system infection.One current focus is to understand theclinical manifestations and molecularepidemiology of Powassan virus, an emergingtick-borne flavivirus. Another focus isunbiased viral detection using metagenomicsequencing. Projects combineclinical/translational, laboratory, andcomputational approaches.Anne Piantadosi, MD, PhDEmory Vaccine CenterEmory University

Page 7

Dr. Krishnendu (Krish) Roy is the Robert A.Milton Chaired Professor in BiomedicalEngineering. At Georgia Tech, he also servesas the Director of the newly established NSFEngineering Research Center for CellManufacturing Technologies and The MarcusCenter for Cell-Therapy Characterization andManufacturing - as well as the Director of theCenter for ImmunoEngineering. He is also theTechnical Lead of the NIST/AMTech NationalCell Manufacturing Consortium, a nationalpublic-private partnership, focused onaddressing the challenges and solutions forlarge scale manufacturing of therapeuticcells. Dr. Roy’s research interests are in theareas of scalable cell manufacturing,Immuno-engineering, stem-cell engineeringand controlled drug and vaccine deliverytechnologies, with particular focus inbiomedical materials. In recognition of hisseminal contributions to these fields, Dr. Royis elected Fellow of the American Institute forMedical and Biological Engineering and theBiomedical Engineering Society. In addition,Dr. Roy has received numerous awards andhonors including Young Investigator Awardsfrom both the Controlled Release Society andThe Society for Biomaterials, NSF CAREERaward, Global Indus Technovator Award fromMIT, the CRS Cygnus Award etc. e is also therecipient of Best Teacher Award given by theBiomedical Engineering Students at UT-Austin and the best advisor award given bybioengineering students at Georgia Tech.Krish Roy, PhDWallace H. Coulter Dept. of Biomedical Engineering Georgia Institute of TechnologyHe serves as a member of the EditorialBoards of the Journal of ControlledRelease, the European Journal ofPharmaceutics and Biopharmaceutics,the Journal of Immunology andRegenerative Medicine, all fromElsevier, as well as the AIChE Journal ofAdvanced Biomanufacturing andBioprocessing. He is a member of theForum on Regenerative Medicine of theNational Academies of Science,Engineering and Medicine (NASEM),and a Board Member of the StandardsCoordinating Body (SCB) for Cell andRegenerative Therapies.

Page 8

Fred Sanfilippo, MD, PhD directs the Emory-Georgia Tech Healthcare Innovation Program,which has a mission to accelerate innovationin healthcare research, education, andservice. He also serves as Professor ofPathology and Laboratory Medicine andHealth Policy and Management at Emory, andMedical Director of the Marcus Foundation.For over 30 years he has been an academicleader at Duke, Johns Hopkins, Ohio State andEmory; serving as a division chief, departmentchair, program/center director, dean, medicalcenter CEO, university senior/executive VP,health system board chair and academichealth center CEO. During that time he hasled organizational and cultural changesyielding improved academic, clinical, andfinancial performance at each institution. Healso led the creation of the US ScientificRegistry of Transplant Recipients; JohnsHopkins Medical Labs; a personalized healthplan (YP4H) at OSU; and novel departmentsand centers in areas ranging from BiomedicalInformatics to Personalized Health andIntegrative Medicine. Sanfilippo received his BA and MS in physicsfrom the University of Pennsylvania, and hisMD and PhD in immunology from Duke,where he also did his residency training,receiving board certification in Anatomic &Clinical Pathology, and Immunopathology. Fred Sanfilippo, MD, PhDEmory-Georgia Tech Healthcare Innovation ProgramEmory UniversityHe has mentored 33 graduatestudent and fellows, served on 13editorial boards, published over 250articles, received three patents, andbeen awarded over $30 million insponsored research. He has beenboard chair of five non-profits, andpresident of seven academic andprofessional organizations includingthe American Society of InvestigativePathology and the American Societyof Transplantation.

HIP Symposium 33

Page 1