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Congress 2023 www.iat.org.uk 21st March – 24th MarchAnimal Technology – supporting the Technician CommitmentCongress 2023CONGRESS21st March – 24th March

Enquiries to Congress Committee via congress@iat.org.uk Come and join us atCongress 202411th - 14th MarchNORTH UK VENUEDelivering a Full Scientific Programme addressing current themes Attend the wide range of Scientific Papers and Poster DisplaysVisit one of the largest Trade Exhibitions in the UKThe event will take place in a tried and tested conference venueDetails for Congress 2024 will be available on the IAT website www.iat.org.uk and published in the monthly BulletinBookings will open September 2023The largest UK event run entirely for Animal Technologists and TechniciansCongress 2024CONGRESSCongress 2023CONGRESS21st March – 24th March

GENERAL INFORMATION Contacts 2Welcome from the Congress Committee 5Congress App 6CPD Entitlement 9Best Poster Prizes 2023 11Andrew Blake Tribute Award 2023 12Animal Technology and Welfare Journal Prize 2022 14AAALAC International Fellowship Award 18Annual General Meeting Agenda 21Cambridge and Edinburgh Branches Charity 2023 Appeal 22Index to Advertisers 95Sponsorship 110Congress 2024 IBCSCIENTIFIC PROGRAMME At A Glance Tuesday / Wednesday 26At A Glance Thursday 28Paper Presentations 33Kevin Dolan Memorial Lecture 54Workshop Sessions 56Poster Presentation 69Poster Displays 70SOCIAL PROGRAMME Events and Entertainment 82TRADE EXHIBITION Flash Trade Presentations 84Trade Competition 85Trade Exhibition Plan 86Trade Exhibition Listings 87Exhibiting Companies 88Animal Technology – supporting the Technician CommitmentThe IAT roundel logo is a registered trademarkof the Institute of Animal TechnologyCONGRESS 2023 CONTENTS

Animal Technology – supporting the Technician CommitmentCONGRESS 2023 CONTACTSDuring Congress, the Committee can be contacted via the Congress ReceptionAfter Congress, contact should be made via email to: congress@iat.org.ukRegistered Office:Institute of Animal Technology, 5 South Parade, Summertown, Oxford OX2 7JL, UK© Copyright Institute of Animal Technology 2023 All rights reserved; no part of this handbook may be reproduced, by any means without prior written permission of the Institute of Animal Technology and the Publisher. Reproduction in whole or part without the express written permission of the copyright holders is prohibited.This HANDBOOK is highly confidential. Please DO NOT leave it unattended during Congress.All information contained is correct at the time of going to pressPublished on behalf of IAT Congress 2023 by PRC Associates LtdDesigned and Printed in Great Britain

General Information5WELCOME Welcome to Congress 2023Dear DelegateThis year sees a return to a favourite venue – Celtic Manor. It ticks so many boxes – all under one roof, keeping delegates together with a wonderfully high standard of accommodation and refreshments. We have worked hard to put together a scientific programme to address all your learning needs plus a number of excellent posters on display. Workshops have proved as popular as ever, with waiting lists for most of them.The trade exhibition is fully booked and the exhibitors are keen to meet everyone to show off their products and innovations and also to catch up with old friends and make new ones. Why not pay a visit to the IAT stand in the exhibition hall, and chat to Council members. Maybe you are thinking of standing for Council next year and want to ask what it involves? Or perhaps you have a query about what Council members do? Come along and meet some Council members and find out!IAT Education has undergone many changes over the years. If you would like to find out about current qualifications and how to achieve them, then come along to the IAT stand and book a slot to talk to someone.We are delighted that the Andrew Blake Tribute Award winner for 2023 is attending Congress to receive this award. Alicia Kinally is the 2023 winner, for her poster entitled ‘Validating the use of box training as a refinement to rabbit handling’. Alicia will be giving an oral presentation on her poster at 14.30 on Thursday afternoon. Please come along and support her.Congress 2023 will culminate in the Gala Dinner on Thursday evening. Please make sure you hand in your dinner dance ticket before the morning refreshment break on Thursday – either to a trade company if you are invited to sit on their table, or to the Congress Reception to reserve your seat.We wish you a very enjoyable Congress. As always, we are keen to receive your feedback or any comments. We will send out a survey on Monday when you are back at work. Please take a few moments to complete it to help us provide improved Congress events in future years.We hope you find Congress 2023 interesting, stimulating and enjoyable!IAT Congress Committee

General Information6GENERAL INFORMATIONCONGRESS APPThe Congress 2023 App allows delegates to plan their scientific attendance, interact with each other and provides all the details needed to enjoy the Congress experience.

GENERAL INFORMATION7General InformationTHE VENUEThis year all delegates will be accommodated under one roof. All activities will also be taking place in the main conference venue. Further details and timings are contained in this Handbook.CONGRESS RECEPTIONThe Congress Reception can be found in the Foyer to the Caernarfon Suite (location for the Trade Exhibition) on Level C1.The desk will be open as follows:Tuesday 21st 10.00 – 17.45 Wednesday 22nd 08.00 – 17.00 Thursday 23rd 08.00 – 13.00 INTRODUCTION TO CONGRESSIs this is your first time at Congress?Or would you just like to know where you are going?Then come along to the Beaumaris Lounge on Tuesday afternoon at 17.00 and members of the Congress Committee will give you an insight and answer as many questions as you have!AGMThe 37th Annual General Meeting of the Institute of Animal Technology will be held in the Beaumaris Suite (Conference Level 2) on Tuesday at 18.00. A full agenda appears on page 21 and attendance is open to ALL delegates.MEALSBreakfast 07.00 – 09.00 Wednesday and Thursday 07.00 – 09.30 FridayBuffet Lunch: 13.00 – 14.00 Wednesday 13.00 – 14.00 ThursdayLunch on both days will be served in the Trade Exhibition (Caernarfon Suite).On Tuesday evening, dinner will be served in the Trade Exhibition Hall at 19.00 hours. This will be a buffet dinner with a wine reception marking the official opening of the Trade Exhibition.Dinner on Wednesday evening will be served at 19.30 in The Grill Restaurant at the Golf Club on site.Thursday’s Gala Dinner Dance will start at 20.00 and will be held in the Hall on the lower ground floor of the conference centre. Please note that the dress code is smart (i.e. no jeans or trainers please) for the dinner dance.Gala Dinner tickets need to have been pre-booked.

General Information8GENERAL INFORMATIONGala Dinner TicketIf you have booked to attend, you will receive your ticket for the Gala Dinner when you arrive at Congress and collect your badge, bag, etc.Exhibiting companies will sometimes invite you to join their table for the Gala Dinner and in this instance you should hand them your ticket stub so they can reserve a place for you. If you do not wish to join an exhibitor’s table, or if you have come to Congress on your own and are unsure of where to sit, please see a member of the Congress Committee prior to the morning refreshment break on Thursday, who will be happy to help you find a seat.Table plans for the Gala Dinner will be available at the Congress Reception from 10.30 on Wednesday (coinciding with the morning refreshment break). TEA AND COFFEERefreshments will be served at the following times:Wednesday 10.30 – 11.00 Trade Exhibition Hall 16.00 – 16.30 Trade Exhibition HallThursday 10.30 – 11.00 Trade Exhibition Hall 15.30 – 16.00 Foyer – Caernarfon SuiteTRADE EXHIBITIONThe Trade Exhibition is situated in the Caernarfon Suite (Conference Level 1) within the main conference centre. Opening times:Tuesday 19.00 – 22.30 (Official opening)Wednesday 09.30 – 17.00 Thursday 09.30 – 14.30 A plan of the Trade Hall and the Exhibitors appear on pages 86 and 87.FLASH TRADE PRESENTATIONSThese take place at 16.30 on Tuesday afternoon in the Beaumaris Suite.See the main programme details on page 31 with a list of companies participating this year on page 84.

GENERAL INFORMATIONGeneral Information 9Trade CompetitionThere is a question at each stand taking part for you to get the answer to. It might be on the stand, about the company, or about the product…you’ll need to ask someone on the stand. Don’t be worried though, they love to talk! Your entry form is in your Congress Delegate bag. Once you have completed it, hand it to Nicky Windows at the Datesand stand by 12 noon on Thursday and you could be walking away with 1 of 2 Amazon vouchers. It’s as easy as that… so what are you waiting for! Also see page 85.Advice on recording your CPD at CongressContinuing Professional Development (CPD) demonstrates your commitment to your role in upholding the IAT ethical statement. By undertaking CPD you show that you are striving to improve your knowledge and keep up to date with new technologies and developments within the care and welfare of laboratory animals.The IAT CPD system is maintained online, via the members’ area of mySociety and we would encourage you to upload each activity as it is completed, rather than wait for the end of the year.Activities can fall under one of the five areas below:1. Work based learning2. Professional activity3. Formal/Educational4. Self-directed learning5. OtherWhen you select the area your activity falls under, you will also be shown various sub-categories for your activity. Once selected, this will allocate the appropriate number of points that can be claimed for each hour you have spent on your activity.Further details on the allocation of points can be found on the IAT website - https://www.iat.org.uk/cpd

GENERAL INFORMATIONGeneral Information10LECTURES AND PAPERSThe Platform Programme will be held in the Beaumaris Suite.Please refer to pages 33 and 52 within the Scientific programme section for information on the Paper presentations.The Kevin Dolan Memorial Lecture this year will be given by Matt Pettit on Thursday at 16.00. The abstract for his paper, entitled A glimpse into the weird and wonderful world of ART can be found on Page 54. We thank IPS for their continued sponsorship of the Kevin Dolan Memorial Lecture.WORKSHOPS Registrations for the twelve workshops taking place during Tuesday, Wednesday and Thursday were available to be pre-booked online. Everyone who has registered must confirm their attendance at the Congress Reception.Reviews on each workshop and the presenters start on page 56.All workshops are IAT CPD accredited with 4 pointsawarded for each two hour session.Workshop 1 – A practical viewpoint of working with Home Cage Monitoring systemsWorkshop 2 – Prepare to present for the first timeWorkshop 3 – Refining wound closure using intradermal stitches – a practical learning lessonWorkshop 4 – Focus on aquatic animals – current issues in regulation, ethics and welfareWorkshop 5 – The principles of IVCsWorkshop 6 – Confidence is key – evaluating environmental enrichment for improved Animal WelfareWorkshop 7 – Lessons from a Meerkat – tips and tricks to engage your traineesWorkshop 8 – Catheter patency strategies during surgeryWorkshop 9 – Speaking upWorkshop 10 – IAT EducationWorkshop 11 – Using your smartphone to film your workWorkshop 12 – The ‘Roadmap’ to refinement

GENERAL INFORMATIONGeneral Information11BEST POSTER PRIZES This year’s posters on display sees a range of topics addressing varying research themes. All posters will be exhibited on Tuesday, Wednesday and Thursday in the Caernarfon Suite Foyer.Two awards will be given for Best Poster based on the criteria for Animal Welfare and Scientific Basis.The two best posters are selected by a panel, nominated by the Congress Committee, who judge each poster according to criteria for best content, clarity and quality of science.The criteria covers: improvement in animal welfare, innovation, ease of replication of work, presentation and layout.LBS Serving Biotechnology continue their generous sponsorship providing the two cash prizes of £250.00 each and the winners for both categories will be announced at the Close of Congress on Thursday afternoon.Poster Authors will be in attendance for you to interact and engage with them on their poster contributions at these times:Wednesday 16.00 – 16.30Thursday 15.30 – 16.00There is one Poster Presentation by John Hobbs and Sylvie Mehigan from University College Dublin taking place at 15.00 on Wednesday. Further details on pages 69.The ABTA winning poster will also be presented at 14.30 on Thursday afternoon. See pages 12 and 13.Abstracts for the Poster Displays appear on page 70 onwards.PRIZES AND AWARDSCongress 2023Congress 2023BEST POSTER WINNER ON ANIMAL WELFAREBEST POSTER WINNERFOR SCIENTIFIC BASIS

12 General InformationANDREW BLAKE TRIBUTE AWARD 2023We all have a responsibility for the welfare of the animals in our care and it is often the little things that make a signicant difference. The Andrew Blake Tribute Award is awarded by the Institute of Animal Technology and sponsored by The Association of the British Pharmaceutical Industry (the ABPI) to an Animal Technologist at any level, judged to have made a signicant contribution to improving laboratory Animal Welfare.The 2023 worthy winner is:Alicia Kinally Division of Biomedical ServicesUniversity of LeicesterFor her poster:‘Validating the use of box training as a renement to rabbit handling’ Alicia will present her paper on Thursday afternoon at 14.30.She will receive an engraved plaque and the total cash award of £250.00.ANDREW BLAKETRIBUTE AWARDANDREW BLAKETRIBUTE AWARD

13General InformationANDREW BLAKE TRIBUTE AWARD 2023The Andrew Blake Tribute Award commemorates the work and life of Andrew Blake, who suffered from Friedrich’s ataxia, a hereditary condition described as one of the “worst of neurological diseases”. Andrew died in May 2002 aged 39. Andrew was passionate about the need to support scientists in their work and his commitment to speaking out against animal rights activists took up much of the last ten years of his life. He died shortly before he was to collect his MBE.How to Apply for 2024The topic of work that you describe in your application may be undertaken as part of project and presented as a poster / an essay / a project / a scientic paper.The submission, which should contain the content detailed in the Submission Guidelines can be sent via https://www.iat.org.uk/abtaAbout the author:Alicia previously studied animal management at Brooksby Melton College and is now an Animal Technician at the Preclinical Research Facility, University of Leicester. She has been in this role for ve years and has cared for a range of animals including mice, rats, Zebrash and rabbits.Alicia enjoys her job thoroughly. Caring for the animals and constantly understanding more about them as well as learning procedural skills and assisting the scientists with their studies all make it extremely interesting. One of her main passions is improving Animal Welfare and with this interest came improving the handling method for rabbits through box training. The positive impact on the rabbits’ overall temperaments and behaviours as they explore the box has been a joy to watch.She hopes to work on more projects like this and have the ability to progress further in her career.

General Information14Animal Technology and WelfareMarjorie (Sandiford) Whittingham was a late arrival on Council in 1966 serving 11 years until she retired from work in the late 1970s. For the 7 years prior to her retirement, she was Secretary to the Institute and was also a Member of the Exam Board for all of those 11 years. Marjorie’s husband, Dick Whittingham and Council set up the prize fund after her untimely death in Kenya where they had retired to. The enormity of the amount of work that Marjorie completed during that period made her shorter service even more exceptional.Journal Article – Marjorie (Sandiford) Whittingham Prize 2022Paper AbstractAs animal facility closure is usually a protracted process because of the complexity of finishing or transitioning ongoing research in animals. As with any closure, staff may be made redundant at the end of the process and this can be an emotional roller coaster and distraction. Maintaining positive morale contributes to successful outcomes. We explored ways of maintaining a Culture of Care through the closure of our animal facility.The ATW Editorial Board, chaired by Jas Barley, have selected Sally Robinson and Catherine Wilkinsonas the 2022 winners of the Animal Technology and Welfare Journal Prizefor their paperMaintaining a Culture of Care during a research animal facility closurepublished in the April 2022 issue Vol. 21.1 pp11-16 www.atwjournal.com

15General InformationAuthors Sally RobinsonSally completed both her BSc and PhD in Chemistry and Pharmacology at the University of Liverpool. She worked at AstraZeneca for 26 years mainly within safety assessment. From 2013 she was the Director of the Animal Sciences and Technology team (and the Establishment Licence Holder) supporting oncology in vivo research. She led an initiative to remove the requirement for acute toxicity studies from drug development leading to a revision of ICH M3 guidelines and received an international award for the enhancement of Animal Welfare for this work. She has over 30 publications relating to the application of the 3Rs and Culture of Care in animal research. She has recently completed a master’s in Medical Ethics and Law. She is currently a member of the NC3Rs board. Sally chairs the AWERBs for CRUK MI and the University of Bristol. Sally is passionate concerning the role of AWERBs in promoting a Culture of Care.Catherine WilkinsonCatherine started her career at AstraZeneca 27 years ago carrying out studies with small and large species supporting regulatory safety work whilst gaining her IAT Membership (MIAT) and BSc (Hons) Natural Sciences with the OU. With a keen interest in regulatory compliance and operational support she transitioned towards the role of Regulatory Manager at Alderley Park, fulfilling the roles of Named Training and Competency Officer (NTCO), Named Information Officer (NIO), Home Office Liaison Contact (HOLC) and AWERB secretariat. She is passionate about supporting the teams within the Animal Care and Use Programme and key highlights have been implementing a new training programme and working with the team developing their learning log to support Culture of Care.A commemorative plaque and monetary gift of £250.00 will be awarded to the deserved winners at the Awards Ceremony during the Close of Congress on Thursday afternoon in the Beaumaris Suite. Animal Technology and Welfare

General Information18Call for nominations now open for the popular2023 AAALAC International Fellowship UK AwardIf you are an IAT Registered Technologist (RAnTech) apply by 1 June 2023The AAALAC International Fellowship recognises two outstanding individuals – one IAT Registered (RAnTech) and one AALAS or CALAS (Canada) Registered (RALAT, RLAT, RLATG, CMAR, ARLAT, RMLAT) – who have made (or have the potential to make) significant contributions to the field of laboratory animal care and use. This Fellowship is valued at more than £3,000. The UK winner will receive a week-long guest visit to prestigious biomedical research facilities in the USA this Autumn, plus complimentary attendance at the National AALAS Meeting, the USA’s largest laboratory animal science and technology meeting being held in Salt Lake City, Utah. All registration, travel, accommodation, meals and out-of-pocket expenses are covered (receipts are required).TO APPLY:1. Write a brief letter nominating yourself (or have someone write this letter on your behalf). 2. Include a 500-word written statement describing why you should be selected. 3. Include a copy of your CV. 4. Include no more than three letters of support. TIPS:Be sure to address these points in your application… – What have you done to promote animal welfare and refinement in your workplace? (i.e. involvement in AWERB, training others, advising on refinement, etc) – What have you done to promote animal welfare and refinement outside of your workplace? (i.e. IAT activities, school visits, public presentations, etc) – How have you shared your knowledge of laboratory animal care with others? (i.e. lectures, posters, workplace projects, etc) – If you are selected, how will this award benefit your career and your associates? – How will you translate this experience back to your workplace and your local association? – Does your package include evidence of leadership or leadership potential and participation with posters, presentations or publications? – Based on your experience, what role does AAALAC International play in ensuring the humane treatment of animals in science? Describe your interactions with AAALAC International (e.g. participated in a visit, helped prepare your organisation/workplace for a site visit, reviewed the information on the AAALAC International website such as the FAQs, position statements, newsletters, attended an AAALAC presentation, etc)? – Have you participated in overseas meetings in the past?Awardees are expected to share their experiences briefly by preparing a written report for AAALAC International and a full report for publication in the IAT Bulletin.Awardees are also expected to communicate their experiences to peers by presenting at a local or national conference (i.e. branch meeting or Congress). Apply online www.aaalac.org/awards/fellowship.award/ 1 June 2023 If you have any questions email: fellow@aaalac.orgFor complete details and a list of selection criteria, visit www.aaalac.orgor email fellow@aaalac.org.The AAALAC International Fellowship Award is presented by AAALAC International through grants from Datesand Group Ltd, in cooperation with AALAS, IAT, MRC and NIH.Don’t delay get your application in now!Individuals interested in applying for the Fellowship Award are expected to consider both real (i.e., financial or other personal or professional considerations, such as employment at AAALAC International or Datesand Group Ltd) and perceived (i.e., an appearance of being at an advantage) conflicts of interest before submitting their applications. Questions regarding a potential conflict of interest may be directed to the AAALAC international Chief Executive Officer, Dr. Kathryn Bayne (kbayne@aaalac.org).

GENERAL INFORMATIONGeneral Information19Valerie A. Hill BS, CMAR, LATG - 2023 USA AAALAS recipient Valerie currently serves as the Chief Department Administrator/Director Campus Animal Resources for the Unit for Laboratory Animal Medicine (ULAM) at the University of Michigan Office of Research in Ann Arbor, Michigan. There she provides guidance to individuals conducting animal activities under the auspices of the University of Michigan, ensuring ULAM’s activities are compliant with local, federal and state regulations, assists in developing and implementing short- and long-range initiatives and strategic plans, as well as providing general leadership and oversight for the Unit.Prior to her current position Valerie served as Managing Director of Campus Animal Care for the University of Michigan. She has also worked as a veterinary assistant for a veterinary emergency service and animal hospital, both in Plymouth, Michigan. She has authored numerous publications and presentations and is an active member of AALAS. She is the 2021 winner of the Charles River Medallion Award for distinguished contributions to the field of laboratory animal management presented by the Laboratory Animal Managers Association. Valerie received her Bachelor of Science degree in General Zoology from Michigan State University.On Thursday at 15.00, Valerie will present her paper ‘Evolution of a large, complex, decentralised, academic animal care programme’. We hope you will all attend and support her.AAALAC International Fellowship Award

General Information21NOTICE OF AGMTHIRTY-SEVENTH ANNUAL GENERAL MEETING OF THE INSTITUTE OF ANIMAL TECHNOLOGYTo be held Tuesday 21st March 2023 at 18.00 in the Beaumaris SuiteAGENDA1. Apologies for absence2. Minutes of the 36th Annual General Meeting held on Tuesday 29th March 20223. Matters arising from the Minutes (as published in full on the Members’ section of the IAT website and in abridged form in the Bulletin Vol. 58 No. 6).4. Correspondence5. Annual Report / Council Objectives6. Financial Report7. Appointment of the Auditor 8. Education proposal for Fellowship by thesis 9. Election of Officers: (i) President (ii) Vice Presidents (iii) Council 10. Proposals for Honorary and Life Memberships11. Any other businessTHE AGM IS OPEN TO ALL DELEGATESVoting rights are restricted to voting members only1 Kally Booth2 Alan Graham3 Adele Kitching4 Robin Labesse5 Theresa Langford6 Sylvie Mehigan7 Claire Pearce8 John Waters9 Lynda Westall10 Carole WilsonCOUNCIL ELECTIONS 2023There were ten nominations for ten vacancies on Council and therefore no ballot took place. The nominees were as follows: Linda HoranCEO & Chair of CouncilSimon Cumming Honorary Secretary

AS-ET is extremely grateful and appreciative to be chosen again this year to benefit from the IAT Congress Raffle.The Trust thanks both the Cambridge and Edinburgh Branches for organising it, all the Branches for donating prizes and ALL OF YOU for your support by buying tickets.By awarding bursaries to enable individuals to attend courses to improve their own knowledge and skills, directly leading to ever improving standards of animal welfare, AS-ET has also awarded grants to support research projects and the development and provision of short courses and educational meetings.During the past 10 years AS-ET has distributed over £180K in grants to support education and welfare activities but we are entirely dependent on funds donated from those employed in or having an interest in Animal Technology.2023 CHARITY NOMINATED BY CAMBRIDGE AND EDINBURGH BRANCHESwww.as-et.org.ukAS-ET is a charity with the purpose to further the advancement of education and promotion of excellence in the welfare of animals in science Trustees of AS-ET - Professor Sir Richard Gardner and Charlie Chambers

Patron: Professor Lord Naren Patel KT Chair of Trustees: Professor Sir Richard Gardner FIAT (Hon) FRS Secretary to the Trust: Ken Applebee OBE FIAT FRSBTrustees: Jasmine Barley MSc FIAT RAnTech, Charlie Chambers MIAT, Karen J Gardner, Wendy Steel BSc (Hons) FIAT, Allan Thornhill FIAT RAnTech Registered Charity Number 1133119Registered Ofce: 5 South Parade, Summertown, Oxford OX2 7JLHere’s what some of our bursary winners have to say:“I would like to thank AS-ET for the financial support and consideration given to me, which has allowed me to embark on and complete my MSc degree. The new knowledge gained has let me become a more rounded and complete technician, with confidence to help others with their educational requirements, and to better support the research projects” “With rising prices everywhere, our departmental budget wasn’t able to stretch to me studying a Level 4 module. I turned to AS-ET for help and they willingly agreed to part fund the course. For anyone debating to give a Level 4 unit a try I would say go for it! You will learn so much about the science behind the work going on in your facility as well as essay writing techniques and working to deadlines”“Due to COVID constraints, my department could not fund me to attend an NTCO Workshop, so I turned to ASET for support and, within two days, ASET responded to say I had been granted a bursary. The skills and support I have gained have empowered me to further influence and inspire those working with animals at my workplace to achieve the highest standards of training and welfare”“Thanks to AS-ET, I have been able to attend a NACWO course and now have a broader knowledge on legislation, ethical issues, project licence review and the NACWO contribution to AWERB. The bursary enabled me to further my education within Animal Technology which in turn has progressed my career. I now hold a more valued position at my establishment which benefits both myself and my employer”Emma MustafaInstitute of Cancer Researchreceiving her IAT HE Level 5 prize from Professor Sir Richard Gardner FRSMichelle ScutterKing’s College Londonbeing presented with the John Walton Prize for IAT HE Level 6

GENERAL INFORMATIONGeneral Information24CONGRESS BADGESIt is important that you wear your badge at all times within the conference venue. You will not gain access to the Exhibition Hall, Papers, Posters and Workshops if you are not wearing it. Please also make sure you are wearing it at meal times and for all of the social events. If you are not wearing it admittance will be refused.We do however recommend you remove your badge when you leave the conference venue but please remember it for evening functions.If you lose your badge, please report your loss immediately to a member of the Congress Committee.MOBILE PHONES AND PAGERSOut of courtesy to speakers and other delegates, pagers and mobile phones must be switched off or put on non-audible alerts BEFORE entering the main lecture theatre and the areas hosting the posters and workshops.Mobile phones and mobile phone cameras MUST NOT be used in any of the scientific sessions at Congress.ENQUIRIESIf you have any questions or comments regarding Congress, please direct them to the Congress Reception.

General Information25IAT BRANCHESYOUR BRANCH NEEDS YOU - COME ALONG AND GET INVOLVED If you don’t know about the IAT Branches, or if you do but would like to find out more, come along and meet some Branch members. Our Branches are only able to function with your involvement.They will be in attendance at the IAT Branch poster displayed by the IAT stand. at the following times:Wednesday:10.30 – 11.00 / 13.30 – 14.00 / 16.00 – 16.30 Thursday:10.30 – 11.00 / 13.30 – 14.00The IAT Branch Map will also be on display to help you decide which Branch is right for you.Branches are always keen for people to join the Branch Committees, but just as happy for enthusiastic members to join the Branch.Please support your local Branch – we need you!CambridgeHuntingdon,Suffolk and NorfolkSurrey, Hampshireand Sussex LondonWest Middlesex North East of EnglandNorth Westof EnglandMidlandsEdinburghWest of ScotlandIreland Hertfordshireand EssexOxford Institute of Animal TechnologyIAT BRANCHES

Scientific Programme26TIME TUESDAY 21st MARCH10:00Registration Opens – Congress Reception – Caernafon Suite Foyer14:00W1 A practical viewpoint - Home Cage Monitoring systemsW3 Refining wound closure using intradermal stitchesW2 Preparing to presentW4 Focus on aquatic animals14:3015:0015:3016:0016:30 Flash Trade Presentations - Beaumaris Suite17:00 Introduction to Congress - Beaumaris Lounge17:3018:00 AGM – Beaumaris SuiteTIME WEDNESDAY 22nd MARCH09.00 – 09.05 Opening AddressPoster Displays Foyer Caernarfon Suite09.05 – 09.35 Ken Applebee/Carmen Abela - IAT Education – A new beginning academic year 2023-2024Trade Exhibition09.35 – 10.05 Robin Labesse/Diane Hazlehurst – The modern apprenticeship10.05 – 10.30 Serena Hettiarachchi – My experience as an Animal Technician apprentice10.30 – 11.00Refreshments – served in Exhibition Hall11.00 – 11.30 Simon Breeden – The Technician CommitmentW5 The principles of IVCsW6 Confidence is keyW7 Lessons from a MeerkatW8 Catheter patency strategies11.30 – 12.00 Wendy Jarrett – How openness can help support12.00 – 12.30 Haley Daniels – A psychological contract12.30 – 13.00 Keith Davies – Emotional challenges faced13.00 – 14.00 Lunch – Exhibition Hall14.00 – 14.30 Selina Ballantyne – Using root cause analysisW9 Speaking upW10 IAT Education End Point AssessorsW11 Using your smartphoneW12 The ‘Roadmap’ to refinement14.30 – 15.00 Matthew O’Brien – Refinement of ear notching15.00 – 15.30 Poster Presentation John Hobbs/Sylvie Mehigan - 3Hs15.30 – 16.00 Christopher Huggins – Animal Welfare management16.00 – 16.30 Refreshments – served in Exhibition Hall Poster Authors in attendance – Foyer Caernarfon Suite16.30 – 17.00 Harry Gilbert – Investigating bedding effectiveness17.00 – 17.30 Georgio Rosati – Unveiling stress-broken biomarkers17.30 – 18.00 Magdalena Czubala – Animal tissue sharingAT A GLANCE FULL PROGRAMME

Scientific Programme27TIME TUESDAY 21st MARCH10:00Registration Opens – Congress Reception – Caernafon Suite Foyer14:00W1 A practical viewpoint - Home Cage Monitoring systemsW3 Refining wound closure using intradermal stitchesW2 Preparing to presentW4 Focus on aquatic animals14:3015:0015:3016:0016:30 Flash Trade Presentations - Beaumaris Suite17:00 Introduction to Congress - Beaumaris Lounge17:3018:00 AGM – Beaumaris SuiteTIME WEDNESDAY 22nd MARCH09.00 – 09.05 Opening AddressPoster Displays Foyer Caernarfon Suite09.05 – 09.35 Ken Applebee/Carmen Abela - IAT Education – A new beginning academic year 2023-2024Trade Exhibition09.35 – 10.05 Robin Labesse/Diane Hazlehurst – The modern apprenticeship10.05 – 10.30 Serena Hettiarachchi – My experience as an Animal Technician apprentice10.30 – 11.00Refreshments – served in Exhibition Hall11.00 – 11.30 Simon Breeden – The Technician CommitmentW5 The principles of IVCsW6 Confidence is keyW7 Lessons from a MeerkatW8 Catheter patency strategies11.30 – 12.00 Wendy Jarrett – How openness can help support12.00 – 12.30 Haley Daniels – A psychological contract12.30 – 13.00 Keith Davies – Emotional challenges faced13.00 – 14.00 Lunch – Exhibition Hall14.00 – 14.30 Selina Ballantyne – Using root cause analysisW9 Speaking upW10 IAT Education End Point AssessorsW11 Using your smartphoneW12 The ‘Roadmap’ to refinement14.30 – 15.00 Matthew O’Brien – Refinement of ear notching15.00 – 15.30 Poster Presentation John Hobbs/Sylvie Mehigan - 3Hs15.30 – 16.00 Christopher Huggins – Animal Welfare management16.00 – 16.30 Refreshments – served in Exhibition Hall Poster Authors in attendance – Foyer Caernarfon Suite16.30 – 17.00 Harry Gilbert – Investigating bedding effectiveness17.00 – 17.30 Georgio Rosati – Unveiling stress-broken biomarkers17.30 – 18.00 Magdalena Czubala – Animal tissue sharingAT A GLANCE FULL PROGRAMMEEvents Trade Sessions WorkshopsPresentationsKEY

Scientific Programme28AT A GLANCE FULL PROGRAMMETIME THURSDAY 23rd MARCH09.00 – 09.30Kate Chandler and Will Reynolds, ASRU - Home Office UpdatePoster Displays Foyer Caernarfon Suite09.30 – 10.00Trade Exhibition10.00 – 10.30Tom Hussey – Schedule 1 euthanasia of farm animals10.30 – 11.00Refreshments – served in Exhibition Hall 11.00 – 11.30Rue Jones-Green – African clawed frogW6 Confidence is keyW10 IAT Education End Point AssessorsW11 Using your smartphoneW12 The ‘Roadmap’ to refinement11.30 – 12.00Steven Trim – Managing invertebrates12.00 – 12.30Richard Gardner – Mary Lyon’s brilliant conjecture12.30 – 13.00Seonagh Henderson – Sifting bedding13.00 – 14.00Lunch – Exhibition Hall14.00 – 14.30Chloe Stevens – Enrichment for laboratory Zebrafish14.30 – 15.00ABTA 2023 - Alicia Kinally – Box training for rabbits15.00 – 15.30AAALAC Fellowship – Valerie Hill15.30 – 16.00Refreshments – served in Foyer Caernarfon Suite Poster Authors in attendance – Foyer Caernafon Suite16.00 – 16.30KDMLMatt Pettit – The wonderful world of ART16.30 – 17.0017.00 – 17.30Awards Ceremony and Close of Congress

Scientific Programme29AT A GLANCE FULL PROGRAMMETIME THURSDAY 23rd MARCH09.00 – 09.30Kate Chandler and Will Reynolds, ASRU - Home Office UpdatePoster Displays Foyer Caernarfon Suite09.30 – 10.00Trade Exhibition10.00 – 10.30Tom Hussey – Schedule 1 euthanasia of farm animals10.30 – 11.00Refreshments – served in Exhibition Hall 11.00 – 11.30Rue Jones-Green – African clawed frogW6 Confidence is keyW10 IAT Education End Point AssessorsW11 Using your smartphoneW12 The ‘Roadmap’ to refinement11.30 – 12.00Steven Trim – Managing invertebrates12.00 – 12.30Richard Gardner – Mary Lyon’s brilliant conjecture12.30 – 13.00Seonagh Henderson – Sifting bedding13.00 – 14.00Lunch – Exhibition Hall14.00 – 14.30Chloe Stevens – Enrichment for laboratory Zebrafish14.30 – 15.00ABTA 2023 - Alicia Kinally – Box training for rabbits15.00 – 15.30AAALAC Fellowship – Valerie Hill15.30 – 16.00Refreshments – served in Foyer Caernarfon Suite Poster Authors in attendance – Foyer Caernafon Suite16.00 – 16.30KDMLMatt Pettit – The wonderful world of ART16.30 – 17.0017.00 – 17.30Awards Ceremony and Close of CongressAT A GLANCE FULL PROGRAMMEEvents Trade SessionsABTAWorkshops AAALACPresentationsKEY

Animal Technology – supporting the Technician CommitmentCongress 2023CONGRESS Invitation to Participate21st March – 24th MarchApprenticeships Diplomas End Point AssessmentsEDUCATION AT CONGRESS 2023 (https://iateducation.co.uk/)From our surveys we know Education, including CPD, is considered to be the most important subject to IAT members.At Congress 2023 IAT Education will be holding workshops, platform sessions and drop-in sessions.- Drop-in Sessions: Prebook an individual session and we will answer your questions and offer advice on all IAT educational and training.- Apprenticeship drop-in sessions, whether you are a prospective apprentice wanting to better understand the benefits, or an employer wanting to navigate the application process we are here to answer your questions. Drop-in sessions can be pre booked, individual or group.- Platform session on Level 2 and 3 giving an overview of Further Education and Apprenticeships.- Platform session on the new Higher Education units.- Workshop: IAT Education is the End Point Assessment organisation for Level 2 and 3 Apprenticeships. In the workshop we will look at the new Apprenticeship Standards and discuss how you can access the best opportunities as the Employer and from the Apprentice in the workplace.

31Scientific ProgrammeCPD WORKSHOP SESSIONS AND MAIN PROGRAMMETuesday 21st March14.00 – 16.00WORKSHOPSW1 A practical viewpoint on working with Home Cage Monitoring systems – details on page 56.W2 Preparing to present for the first time – details on page 57.W3 Refining wound closure using intradermal – details on page 58.W4 Focus on aquatic animals – details on page 60.Chair: Glyn Fisher, Honorary Treasurer, Institute of Animal TechnologyFLASH TRADE PRESENTATIONSBeaumaris Suite16.30 – 17.00This ever popular session is a captivating opportunity for these companies to tell you about their latest products and innovations prior to you visiting their stands.Watch 19 of our trade partners present in just ONE minute each.See page 20 for a running order of companies participating. 17.00Introduction to CongressMeet in the Beaumaris Lounge 18.00 – 19.0037th Annual General MeetingHeld in the Beaumaris SuiteAn agenda appears on page 21.

Scientific Programme32PAPER PRESENTATIONS AND MAIN PROGRAMMESCIENTIFIC PROGRAMME BEAUMARIS SUITEWednesday 22nd March09.00 – 09.05OPENING OF CONGRESSAlan GrahamChair IAT Congress Committee Alan has been a career Animal Technologist since he started work as a junior Animal Technician at the Royal College of Surgeons in 1978. He has worked with an extremely wide variety of species including some exotics, mainly within academia. Alan also has some zoo experience with big cats and venomous snakes, which came about when he managed the Isle of Wight Zoo for a few years back in the 1980s.He now holds a Senior Management position within Cambridge University as one of the Deputy Directors for Facilities and Operations and over his 30 years at Cambridge he has held several different positions under Animals (Scientific Procedures) Act 1986. He was actively involved in the local animal welfare and ethical review process (AWERB) and the recruitment and retention of Animal Technologists within the University, promoting good practice and continued professional development within the workplace.He is currently involved with a couple of local animal management colleges offering work experience placements for young people looking to work with animals in science as a career.Since early on in Alan’s career he was actively involved with the IAT and when working in London was the Branch Secretary for several years, and was subsequently the Chairman of the Cambridge Branch for seven years following his move to Cambridge in 1992. He has held several positions on the IAT Council including Branch Liaison Officer, and was the registrar for our annual conference for many years, and is now as Chair of the Congress Committee, responsible for the sourcing of new venues and the general organisation of what is the largest laboratory animal conference in the UK. This gives him great personal satisfaction when it all comes together, providing the membership and trade with an informative, interactive and safe meeting.

Scientific Programme33PAPER PRESENTATIONS AND MAIN PROGRAMMEChair: Professor Sir Richard Gardner, Past President, Institute of Animal Technology09.05 – 09.35IAT Education – A new beginning academic year 2023-2024This presentation will give a brief overview of the background to and the development of the current IAT Higher Education (HE) Levels 4, 5 and 6 qualifications, including their success and limitations. The main body of the presentation will focus on the new IAT HE Syllabus as Ofqual regulated stand-alone qualifications and opportunities for CPD.Information will also be given on the exciting new partnership between the College of Laboratory Animal Science and Technology (CLAST) and the Mary Lyon Centre Harwell, acting through the Medical Research Council in delivering the IAT HE courses.To conclude, a previous student will give her view of the positive benefits of studying at HE Level, which we believe will be even more enhanced under this new system. Ken Applebee OBEChair Board of TrusteesCollege of Laboratory Animal Science and Technology Ken is currently the CEO of Applebee Advisory, which specialises in vivo management solutions. After starting as a junior Animal Technician in 1972 aged 15, he had a long and successful career in managing research animal facilities, including a ten-year tenure as Director of Biological Services at King’s College London. Ken was re-elected to Council in 2021 and is Chair of the Registration and Accreditation Board and on the Board of Educational Policy. Previously, Ken served two terms as Chair and CEO of Council for nine years and other various roles including Membership Secretary and Honorary Secretary. His current professional activities include Chair of the Board of Trustees College of Laboratory Animal Science and Technology (CLAST) and he is a founding Trustee of Animals in Science Education Trust (AS-ET).For six years until May 2019, Ken was a specialist member of the UK Government’s Animals in Science Committee, including Deputy Chair of the Project Licence Application Subgroup.Ken’s ongoing major interest is the provision and development of education and training for laboratory animal care staff, for which in 2014 he was made an Officer of the British Empire, “for services to Animal Technician Education and Animal Technology”.Carmen AbelaNTCO / ManagerLondon School of Hygiene and Tropical Medicine Carmen joined the industry many years ago as a junior Animal Technician, following the traditional educational route of attending college one day per week. Building on this, she gained IAT and BTEC qualifications along with lots of experience, eventually taking a role as a Senior Technician. After a long break, she decided to continue her studies and through CLAST was able to complete a Level 6 qualification and gain the IAT Fellowship (FIAT). She was awarded the AS-ET John Walton Prize for maintaining the best performance over all four units in the IAT Level 6 course. As NTCO and NACWO she now manages a small unit, finding each day as exciting and rewarding as her first. Over the years she has seen much positive change within the industry, and she remains committed to furthering this work and curbing complacency.

Scientific Programme3409.35 – 10.05The modern apprenticeship: A strong start to the career pathway for employers and employees The IAT is recognised as an Awarding Body by the Office of Qualifications and Examinations Regulation (Ofqual) which regulates qualifications, examinations, and assessments in England.IAT Education (https://iateducation.co.uk/) enables a professional pathway through its commitment of raising professional standards by ensuring its End Point Assessments (EPA) are delivered by highly qualified industry experts, through a rigorous but fair EPA process. IAT Education works with employers and providers to deliver diplomas and EPAs covering several standards via Levels 2 and 3 modern apprenticeships. The IAT Level 2 and Level 3 programme delivers the knowledge to ensure that the EU Directive requirements on having suitable qualified animal care staff is met. Level 2 provides the entry levels for animal care staff to work unsupervised and Level 3 builds on that knowledge/skill base. We offer qualifications that encourage animal care staff and Animal Technologists to develop their knowledge, skills and attitudes to the highest standards of animal care, welfare and good science. IAT diplomas are flexible enough to be delivered in a range of settings, from small providers to large colleges, in the workplace, classroom, or remotely.We will present the pros and cons for both employees and employers to undertake the apprenticeship journey by covering the practical aspects of this journey, for both employer and employee. It will present for example - financial, timings and recruitment tips which will equip you with the required knowledge to make the most of this opportunity.Robin LabesseIAT Education Robin is currently the BRF manager at the University of Surrey where he holds multiple named person roles.He has worked in the UK for more than 10 years, via UCL, the MRC Prion Unit and CRUK and was previously a technician in France. Robin is a RAnTech, MIAT and is Chair of the London branch. He has been a member of IAT Council for the last two years, contributing to the Board of Education and the European Federation of Animal Technologists.Diane HazlehurstIAT Education Diane has worked within the industry for over 30 years. She started at Imperial College, London in 1990 as a junior Animal Technician and rose to Chief Technician where she took on the role of NACWO and demonstrated the practical elements on the Imperial College Personal Licensee Training courses. Diane held a Personal Licence and Project Licence during this time. She then joined the Kennedy Institute of Rheumatology for 2 years as the Divisional Safety Officer which included the animal facility and the laboratory areas. After this she worked at the Wellcome Sanger Institute initially as the Faculty Services manager, overseeing the management of the experimental, containment and quarantine PAPER PRESENTATIONS AND MAIN PROGRAMME

Scientific Programme35PAPER PRESENTATIONS AND MAIN PROGRAMMEareas and when the Named Training and Competency Officer role was introduced under ASPA, Diane took on this and the NACWO roles. She then moved to the NIBSC working in an NTCO role. Until recently, she was Head of Programme for the Animal Technician Programme at S3 Science.Diane is a member of IAT Council and sits on the Board of Education Policy which oversees the IAT educational courses. She is also a member of the Animal Technology and Welfare editorial board where she reviews articles and ATW journal prior to issue publication.10.05 – 10.30My experience as an Animal Technician apprenticeAs a newly qualified and licensed Animal Technician at the Babraham Institute, I became involved in this industry through an apprenticeship via Agenda Life Sciences. I would like to take this opportunity to share my experience of the apprenticeship and how I believe it is an excellent training scheme which combines both practical and theory-based knowledge to produce highly skilled Animal Technicians. I will be discussing how I came to find the apprenticeship, the structure of the apprentice learning plan and what key skills I gained through it. I believe apprenticeships are great way of producing Animal Technicians for the ever-growing field of biological research and to also provide students with a way to jump start their careers and secure a job by the end of it.Serena HettiarachchiAnimal TechnicianBabraham Institute Serena works in the Transgenic Unit within the Biological Support Unit. She completed her apprenticeship and passed the Home Office Licence course late last year. Before working at Babraham, Serena had very little to no knowledge of Animal Technology let alone what an Animal Technician did! It was not until she started her apprenticeship that she began to see how good Animal Welfare leads to good science. It has always been a dream of Serena’s to work closely with animals, so she feels blessed to have secured a career within this industry. She looks forward to the prospects this job will bring her in the future and strives to always improve Animal Welfare and implement the 3Rs where possible. Being very proud of the progress she has made so far in her career and most recently developing her public speaking skills through outreach programmes and here now, at the IAT Congress. Moving forward Serena wants to continue to speak openly about animal research and her role as an Animal Technician.10.30 – 11.00Refreshments served in Trade Exhibition – Caernarfon Suite

Scientific Programme3611.00 – 13.00WORKSHOPSW5 The principles of IVCs – details on page 61.W6 Confidence is key – details on page 62.W7 Lessons from a Meerkat – details on page 63.W8 Catheter patency strategies during surgery – details on page 64.PAPER PRESENTATIONSChair: John Waters, Congress Committee, Institute of Animal Technology11.00 – 11.30Technician Commitment impact and culture The Technician Commitment is a university and research institution initiative, led by a steering board of sector bodies, with support from the Science Council and the Gatsby Foundation. The Commitment aims to ensure visibility, recognition, career development and sustainability for technicians working in higher education and research, across all disciplines. Universities and research institutes are invited to become signatories of the Technician Commitment and pledge action against the key challenges affecting their technical staff.The presentation will give a brief background to the Technician Commitment alongside an update of recent activities highlighting in particular the recent report: Research Culture: A Technician Lens. It will emphasise the importance of visibility of technicians, acknowledging the particular challenges around being an animal technician. It will also discuss the critical importance of networking, mutual support and community to ensure the wellbeing of technicians and support technicians in increasing their (emotional) resilience.Simon BreedenAssociate Lead of Technician CommitmentUniversity of York After a career in research in both the UK and Republic of Ireland Simon was appointed as Operations Manager for the Chemistry Department at the University of York in September 2012. During that time he was responsible for all technical services within the department through leading a team of around sixty technicians. In May 2021 Simon was appointed as Head of Technical Services at the University of York where, with the superb support of a truly excellent team of Technical Operations Managers, he has responsibility for technical services in all academic departments delivered by an exceptional team of well over 200 technicians. Simon has been a passionate supporter of technicians both within and outside of the University of York empowering the teams he works with to deliver excellent technical support and develop skills through continuing professional development.Simon was seconded to the Technician Commitment/Science Council in May 2020 and it is in his role as Associate Lead of Technician Commitment that he will be speaking today. PAPER PRESENTATIONS AND MAIN PROGRAMME

Scientific Programme37PAPER PRESENTATIONS AND MAIN PROGRAMMESimon is a passionate advocate for networking and engaging with colleagues at all levels of an organisation, believing that the most effective way to learn is from understanding other’s successes and, often his own, failures.11.30 – 12.00How openness can help support the role of Animal TechniciansIn the last ten years there has been a concerted effort to improve public communication about the use of animals in scientific research in the UK, driven mainly by the Concordat on Openness. 128 UK organisations have now committed to being more open about their work in this area. That means 128 employers have committed to supporting their employees who want to talk about their jobs and help the public understand more about why and how animals are used and cared for.But openness doesn’t have to be public facing. Just acknowledging that organisations use animals in research, and have staff to care for those animals, has been a big step forward in supporting animal technicians. In-reach can be as important as out-reach in many cases. This presentation will update delegates on how the openness agenda can improve both public understanding and awareness of the critical role that animal care staff play in UK bioscience.Wendy JarrettChief ExecutiveUnderstanding Animal Research Wendy studied Classics at University but has focussed on science and health communication for most of the past 33 years. Her work has included awareness programmes on the risk factors for heart disease, male cancers and a campaign to persuade the UK food industry to reduce the amount of salt added to products. She is a trustee of the Blood Pressure Research Trust. In 2004 Wendy joined the Coalition for Medical Progress (CMP), launching the People’s Petition in support of animal research; creating an image and video library of research animals and encouraging institutions to allow access to news cameras. She led on the merger of CMP with the Research Defence Society to create Understanding Animal Research. In late 2009 Wendy moved to the UK’s National Institute for Heath and Clinical Excellence to introduce a more open approach to media relations, returning to UAR as Chief Executive in November 2012. She led the development of the Concordat on Openness on Animal Research in the UK and worked with colleagues across Europe to set up the European Animal Research Association (EARA) in 2014. In 2022 she has been working with Bella Lear and colleagues in Australia and New Zealand to create UAR Oceania, of which she is the Chair. Wendy sits on the UK’s Animals in Science Committee. She is also a Vice President of the Institute for Animal Technology.

Scientific Programme3812.00 – 12.30A psychological contract of Animal Technicians as dirty workers in the biomedical research industryAnimal Technology is a specialist profession, Animal Technologists are highly skilled, qualified and registered professionals who are deployed in a range of roles in specialist research facilities, in the biomedical research industry across the UK to care for the animals used in research. Their role as a caring professional is to be primarily responsible for the care and welfare of animals used in science in order to ensure that welfare legislation and high standards of animal care are met. It is an incredibly physically and emotionally demanding role which demands ultimate commitment and dedication. Animal Technologists and facility managers who are employed by organisations have a written contract in place but what about the verbal, unwritten, expectations between the employee and employer known as ‘The Psychological Contract’? Typically, these include what employees believe they will receive by way of compensation, benefits, work assignments, organisational support, resources, career development, work–life balance, job security, and interpersonal treatment in return for their talent, effort, performance output and quality, cooperation, loyalty and commitment to the organisation’s objectives.My PhD journey applies the Guest (2004) Psychological Contract framework, a tool for analysing psychological contract theory, exploring all 5 dimensions of the framework through the lens of the Animal Technologist for the first time. This case study aims to provide an in depth understanding of the nature, content and ‘state of the deal’ of the psychological contract focussing on the ‘dirty work’ of Animal Technicians working in medical research facilities throughout the UK. In 2022, I conducted interviews with a number of Animal Technicians and managers of facilities and this talk presents my findings to date and future implications for individuals, organisations and wider society.Haley DanielsBSF ManagerUniversity of York Haley has worked in the animal research industry for over 30 years and managed facilities for over 18 years. During that time Haley has been a driven, motivated leader and mentor, supervising teams of Animal Technologists. She started conducting research in the field of Animal Technology in 2010 for her MBA, specifically focussed on Animal Technician recruitment and retention, leading on to further research in 2013 specifically focussed on psychological contract theory in facility managers for her MSc in HRM and Employment Law.Haley has always been passionate about Animal Technician wellbeing, morale and motivation and is a long standing member of the IAT Council. She sits on the Congress Committee responsible for the organisation of workshops and is also Chair of the IAT EDI group, which is responsible for producing the It’s OK … Not to be Okay series of articles as well as setting up the IAT virtual support network forum for technicians on a weekly basis. PAPER PRESENTATIONS AND MAIN PROGRAMME

Scientific Programme39PAPER PRESENTATIONS AND MAIN PROGRAMME12.30 – 13.00A brief review of emotional challenges faced by Animal Technologists and lessons learnt from the pandemicThis presentation forms part of a panel discussion designed by the Equity, Diversity and Inclusion section of the IAT. Alongside other panel members, the scene will be set with some emotional research constructs, potential management challenges and provide observations on the impact from the pandemic. The presentation will provide some thoughts on personal coping strategies and where institutional culture can play a critical role in mitigation. The aim of the presentation will be to stimulate discussion on topics that might, in some circumstances, be difficult to address within the workplace. However in the convivial environment of Congress, it is hoped the audience will relax and be prompted to share experiences from which colleagues can learn.Keith DaviesConsultant Keith is a career Animal Technologist spanning just over 50 years, with much of his full-time employment spent in the academic sector. In 2019 Keith retired as Operational Director and NTCO at Cardiff University but was not ready to stop working completely. He therefore became self-employed and is now involved in the provision of Personal Licensee and NACWO training courses on a part-time basis. In the latter stages of Keith’s career, he enrolled on an MBA course and his dissertation (2003) explored the potential need for grief counselling to Animal Technologists. This prompted an invitation to take the research to a Doctoral level, which concluded in 2013 at the University of Plymouth. His PhD focussed on the prevalence of emotional dissonance and its subsequent management implications within UK Animal Technologists. Keith has felt privileged and extremely lucky to be able to present the PhD findings at many conferences in the UK and globally. He is also delighted that mental health has now become a focus for the industry at so many levels and applauds those who continue to research and contribute to knowledge that will hopefully protect all those working in the sector.13.00 – 14.00LUNCH – meals and refreshments served in the Caernarfon Suite14.00 – 16.00WORKSHOPSW9 Speaking up – details on page 65.W10 IAT Education End Point Assessors for Level 2 and 3 – details on page 66.W11 Using your smartphone – details on page 67.W12 The ‘Roadmap’ to refinement – details on page 68.

Scientific Programme40Chair: Senga Allan, Vice President, Institute of Animal TechnologyPAPER PRESENTATIONS14.00 – 14.30Using root cause analysis to support reporting of standard condition breachesWhen mistakes occur during the course of working with animals, it is imperative that these incidents are analysed so that any impacts to Animal Welfare, scientific value, A(SP)A compliance and resourcing levels can be understood and reduce the potential of a reoccurrence. Root Cause Analysis (RCA) is a system commonly used in other industries that is applied when a failure in a process or operation occurs. By going through a stepwise process of incident reporting, knowledge gathering and group collaboration focussed on identifying and correcting process failures, University Biomedical Services at the University of Cambridge aim to generate preventative actions to reduce the likelihood of recurrence. Crucially, this should be achieved without apportioning blame to individuals.In this presentation, the theory behind RCAs will be described and how this has been translated to the animal science field. We will give practical examples of RCAs used on husbandry, operational and regulated procedures, and how these have been used to determine underlying root causes. In this way, RCAs can be a central tool for improving the welfare of research animals, refining the use of animals in research and preventing regulatory breaches.Selina BallantyneLicence ManagerUniversity of Cambridge Selina began her career as a trainee Animal Technician for the Medical Research Council in 1999. She spent 8 years at the MRC and during this time gained her IAT Certificate and Membership levels (now Level 2 and 3), Home Office modules 1-3 and presented as a young presenter at Congress in 2001. In 2007, Selina became a supervisor at Cancer Research UK, Cambridge and was part of the team that set up the animal rooms within the new facilities barrier and non-barrier units. She also gained RAnTech status, obtained modules 4 and 5, qualified as a NACWO, while also being the AWERB secretariat and the NIO. In 2013, Selina joined the Wellcome Sanger Institute and was soon promoted to become one of two NACWOs for the facility, where she was heavily involved in leading initiatives on welfare and training and competency. She achieved her IAT Level 4 qualification, a Level 3 award in training and competency and became an Accredited Assessor for Competence under the A(SP)A 1986, specialising in Germ Free animal management and husbandry. Later, Selina was promoted again to Senior Animal Welfare Manager, became the Named Person Responsible for Controlled Drugs and was the institute’s Home Office liaison specialist. She was therefore responsible for ensuring correct archiving of all legal documentation for the animal facility-decommissioning project after it formally closed its doors in September 2021. During her time at Sanger, she led on the development of the incident management system, using Root Cause Analysis as a tool to critically analyse incidents to successfully reduce risk and potential reoccurrence. Since joining the University of Cambridge as a PAPER PRESENTATIONS AND MAIN PROGRAMME

Scientific Programme41PAPER PRESENTATIONS AND MAIN PROGRAMMELicence Manager in January 2022, Selina has been working with the Animal Facility teams to implement a similar system with the aim of supporting the animals, the science and the people when reporting breaches in Standard Conditions to the Home Office.14.30 – 15.00Refinement of an ear notching systemWe want to move away from the old L1, R1, L1R1 (Left, Right) system.The old system used the L1R0, L0R1 system. This means once you are on your third animal, you are already using 2 notches per animal. This then goes up to 3 notches 6+ animals. Most cages can hold up to 5 animals so we wanted to come up with a system that could utilise the animal better.The new system uses less notches to get the same results. We can use 1 notch to identify up to 6 animals. This takes less time to do, so is less stressful for the animal. This is a refinement for the animal and the staff.Matthew O’BrienSenior Animal TechnicianCardiff University Matthew started his career at Oxford University in 2012 in the cage wash and moved to a junior Animal Technician role later that year. He quickly gained his PIL and started learning all sorts of procedures. Matthew completed his IAT Level 2 and Level 3 by 2015 then became a Senior Animal Technician working with many different species including rodents, fish, frogs, ferrets and primates. He won multiple awards for his poster ‘Going on a diet’ and worked to change the Oxford University ear notching code. Matthew then moved back to his hometown, Cardiff in July 2019 and a few months later was employed at Cardiff University. He became a NACWO in February 2020 and has been working to refine the ear notching code. Matthew’s passion has always been the welfare of animals and the 3Rs.POSTER PRESENTATION15.00 – 15.30The 3Hs: home, hammocks and happinessJohn HobbsAnimal TechnologistUniversity College Dublin See page 69 for details.

Scientific Programme42Sylvie MehiganChief Technician Officer 1University College Dublin See page 69 for details.15.30 – 16.00Animal Welfare management in the TikTok ageCan a little app make a big difference?Every Animal Technician knows the importance of Animal Welfare, the impact it can have on the animals, the individuals working with them and the science produced as a result. Time management is essential when dealing with welfare concerns effectively, whether health, environmental or procedural related.The online application Trello was recently implemented in the animal units at Newcastle University to support communication, introduce full audit trails, arrange veterinary treatments, while also monitoring compliance risk and reducing animal suffering. This presentation will look at the journey that Newcastle technicians have taken to adapt and embrace technology for the benefit of the animals in their care.Christopher HugginsRodent Area ManagerNewcastle University Chris been working in animal care and research for almost 30 years mainly based at Newcastle University. He is currently the rodent area manager and NACWO, having started as a trainee technician in 1994. Chris specialises in rodent welfare, care, and procedures. And although he has worked with many other species, rodents are his passion. He manages a team of dedicated technical staff who are very welfare orientated, having been behind implementing practices and policies well above standard levels of care, particularly in low stress handling and GM breeding standards.Since being granted a PIL in 1996, Chris has perfected many regulated procedures, including rodent anaesthesia and small animal surgery. His main areas of focus have been diabetes and cancer based research. As well as being a NACWO, and area manager, Chris is also supervisor for Biological and Radiological safety within the department, although these do appear quite diverse responsibilities, they are a large part of the work the unit carries out.16.00 – 16.30Refreshments served in the Caernarfon SuiteMEET THE POSTER AUTHORS – Foyer, Caernarfon Suite, Level C1PAPER PRESENTATIONS AND MAIN PROGRAMME

Scientific Programme43PAPER PRESENTATIONS AND MAIN PROGRAMMEChair: Klas Abelson, President, FELASAPAPER PRESENTATIONS16.30 – 17.00Investigating bedding effectiveness at ammonia mitigation in individually ventilated cagesBedding substrates are utilised within a number of animal husbandry industries as an essential part of enrichment and waste management, including laboratory environments. Part of waste management is reducing the generation of ammonia, which forms via a hydrolysis reaction of urea from animal urine; high concentrations of atmospheric ammonia can cause lesions within the nasopharyngeal apparatus and irritate or cause permanent damage to the eyes. Utilising four poplar-based bedding varieties of different brand and chip size, we aimed to test the effectiveness of each type at mitigating the generation of ammonia over up to 28 days in individually ventilated cages stocked with CD1 and C57 laboratory mice in groups of 2-5, testing the air within the cages daily with a Portasens II gas sensor to check the ammonia levels.We were unable to determine the most effective bedding variety with complete certainty, with a high variability between the longevity of individual cages on all bedding types. However, when comparing all cages from all cohorts, all types had 5 cages surpass 20ppm by day 8 except the ABP3 bedding, which had 5 cages breach this limit by day 13, suggesting more reliable ammonia mitigation over an extended time period. At lower stocking densities (2-3 animals), all bedding types were able to keep ammonia below potentially dangerous levels for at least 7 days in the majority of cages, however among higher stocked cages (4-5 animals), ammonia levels would tend toward “spiking” above safe limits rapidly, within less than 7 days in some cases. The study suggests the rate at which ammonia builds up may be dependent on a number of factors, besides the number and size of the animals in the cage; behavioural differences between younger and older animals, bedding chip size, manipulation of the cage environment, the presence (or absence) of urease-enzyme producing bacteria and levels of aggression between individuals and subsequent scent-marking may have all had an impact on the rate of ammonia generation. The results also suggest that current cleaning protocols (typically once a week) may result in some cages being exposed to harmful levels of atmospheric ammonia; a more frequent cleaning schedule and reduced stocking density for larger strains (such as CD1 mice) may be necessary to prevent exposure to high ammonia levels.Harry GilbertAnimal TechnicianUniversity College London Harry has been interested in working with animals from a young age, an interest that has followed him throughout life, leading him to achieve a joint honours degree in Zoology and Marine Biology from Bangor University, Wales. He currently works as an Animal Technician with Western Labs, as part of the Biological Services department at the Institute of Child Health, working in tandem with University College London. Harry aims to promote high quality animal care, adhering to the 3Rs principles and assists with research and development of treatments for paediatric disease and cancers by aiding research work and performing regulated procedures.

Scientific Programme4417.00 – 17.30Unveiling stress-broken biomarkers in several mouse models via digital ventilated cages (DVC®) technologiesAdopting home cage monitoring systems allows researchers to discover novel findings due to the 24/7 and in most cases, stress-free environment. Recently, clear definitions between ‘benchtop technologies’ where animals can spend only one to a few days in an environment, and ‘real home cage technologies’ where animals spend 99% of their lifetime, were published by our North American 3R working group.Among real-home cage technologies, digital ventilated cages (DVC®) are the only scalable solution that demonstrated the following:- The possibility of monitoring 1-1000+ cages simultaneously.- Using the animals without amending the animal license because effectively, the animals are staying undisturbed in their home cage while being monitored.- Employing environmental enrichment, which typically disturbs any video assessment, is possible because of our micro electromagnetic field technology.We will present three examples:- Using Polyuria as a surrogate marker of sustained hyperglycemia (diabetes) in type 1 and 2 diabetes. - Identifying unseen fighting events in the home cage in group-housing conditions.- Unveiling early signs of welfare issues in a COVID-19 mouse model before any occurrence of clinical signs or bodyweight loss.Overall, the DVC® technology is allowing scientists to perform 24/7 monitoring in a scalable manner, increasing the welfare aspect while better characterising the models.Giorgio RosatiSenior Product ManagerTecniplast SpA Giorgio is the Senior Product Manager at Tecniplast Italy in the DIGILAB department. An electronic engineer specialised in Bioengineering, he was hired by Tecniplast in 2011 to build up a new digital department devoted to support and complement standard Tecniplast products with digital solutions. He is considered by his colleagues as the “friendly grandfather” of the DVC system, the innovative digital housing solution for mice that is revolutionising the way of housing animals in both facilities and research labs. 17.30 – 18.00An effective approach to animal tissue sharing in researchSince the embedding of the principles of the 3Rs (Replacement, Reduction and Refinement) in national and international regulations on the use of animals, scientists have been challenged to find ways to reduce the number of animals in their research. This presentation introduces a digital platform called ‘3R Blackboard’, linked to a laboratory animal management system, which facilitates sharing of surplus biological materials from animals (e.g. tissues, organs and cells) to other research teams. Based on information provided, such as genotype, age and sex, other animal workers were able to indicate their interest in collecting specific tissues and to communicate with the person providing the animals. A short pilot study of this approach conducted in a limited academic environment presented PAPER PRESENTATIONS AND MAIN PROGRAMME

Scientific Programme45PAPER PRESENTATIONS AND MAIN PROGRAMMEstrong evidence of its effectiveness and resulted in a notable reduction of the number of mice used. In addition, the use of 3R Blackboard led to resource saving, knowledge exchange and even establishment of new collaborations. However, use of the platform at the research establishment scale poses additional limitations. These limitations will be discussed, with their possible solutions as well as highlighting current legal restrictions to effective animal reduction and presenting the initial guidelines of best practice for implementing the approach internationally.Magdalena CzubalaBBSRC Discovery FellowCardiff University Magdalena completed her BSc Hons in Infectious diseases at the University of Edinburgh. In 2016 she successfully passed her PhD viva at Cardiff University, where she was researching molecular biology of HIV-1 infection. Following doctoral study, she became a BBSRC Discovery Fellow at the school of Medicine, Cardiff University, focussing her research on the immune cell communication axis. To date, Magdalena established strong collaborations with numerous national and international laboratories, NHS and companies. Particularly, close collaboration with the animal maintenance software company, a-tune, led to development of the animal tissue sharing software, 3Rs Blackboard, promoting reduction of animal numbers used in research. For this work, Magdalena was awarded the Excellence in Innovation and Enterprise Award from Cardiff University.Chair: Ken Applebee, Life Member, Institute of Animal TechnologyPAPER PRESENTATIONSThursday 23rd March 09.00 – 10.00Home Office Update and Q&A SessionThe use of animals is a fundamental underpin to a significant proportion of leading UK science and innovation. In support of this, government has a strategic aim of having high quality governance over policy and departmental stewardship of the Animals (Scientific Procedures) Act and the delivery of the regulatory framework. Through a focus on strategic regulation, geared towards compliant outcomes, the UK seeks to deliver supportive and open processes. The Home Office will update Congress on its work in this area over the last year and set out future plans.Kate Chandler Head of the Animals in ScienceRegulation Unit, Home Office Kate has worked in the Civil Service for 14 years. Her experience includes leadership of regulatory delivery, change management and policy. Kate undertook a Fulbright Scholarship at New York University and University College London in 2016 to complete the executive Master’s

Scientific Programme46programme on global policy-making and public administration. This built on experience working in the civil service and included work on policy implementation, institutions and governance and public sector reform. In March 2022 Kate was appointed as Head of the Animals in Science Regulation Unit. Kate has previously held the following roles in ASRU: Head of Regulatory Delivery, Chief Inspector, Head of Policy, Principal Inspector, starting off in 2009 as a Home Office Inspector. Before joining the civil service she was a lecturer, clinician and researcher in veterinary neurology and neuroscience at the Royal Veterinary College and UCL.Will Reynolds Head of Animals in Science Policy andCoordination Function, Home Office Will began his career as a marine biologist, gaining 10 years’ experience in marine research for UK Government and internationally, primarily in biological effects techniques. He was later an adviser to the UK Department for Environment chief scientist on animal health and welfare before moving to the Home Office. Will has worked in policy advice as secretary to the UK Advisory Council on the misuse of drugs and as head of UK Advisory Bodies. This role included oversight of the advisory body for the use of animals in science. Will subsequently took up a role as head of policy in the Animals in Science Regulation Unit and is now Head of Animals in Science Policy and Coordination Function.10.00 – 10.30Schedule 1 euthanasia of farm animals- Schedule 1 farm animal methods with captive bolts and electrical stunning. - Conformation of an effective stun followed by pithing or sticking. - Emergency euthanasia on neonates. - Recognising the emotional impact of carrying out euthanasia.Tom HusseyPost Mortem Facilities ManagerUniversity of Surrey Prior to joining the University of Surrey, Tom worked for the Animal and Plant Health Agency for nearly 12 years, starting at the age of 16. He began his career as an Animal Technician after a year and half in post when he was offered the opportunity to train within an ACDP3/SAPO3 high containment post-mortem facility as a Post Mortem Technician. This position involved carrying out post-mortems on a variety of farm animals as well as Schedule 1 euthanasia methods to support research. He was involved in long-term projects such as Bovine Spongiform Encephalopathy (BSE/TSE) and tuberculosis (TB) suspect animal investigations, while at the same time assisting with live animal blood sampling and day-to-day farm animal work in high containment facilities. Throughout Tom’s career he obtained multiple qualifications to support his role including NVQs in Animal Technology in 2010 and a Personal Home Office Licence in 2012. Shortly after becoming the unit’s NACWO (Named Animal Care and Welfare Officer) in 2013, Tom was appointed as the dedicated trainer and assessor on Schedule 1 euthanasia methods in APHA. To further PAPER PRESENTATIONS AND MAIN PROGRAMME

Scientific Programme47PAPER PRESENTATIONS AND MAIN PROGRAMMEsupport this, he obtained his Slaughterman’s Licence (now known as a WATOK Licence) in 2016 to ensure that the highest standards of Animal Welfare were kept whilst carrying out Schedule 1 procedures. In his current role, Tom continues to train undergraduate veterinary students in the safe use and maintenance of captive bolts and other relevant schedule 1 methods, while managing the day to day operations of the post-mortem facilities. This includes carrying out farm animal surveillance, post-mortem investigations for the south east of the UK on behalf of APHA, as well as offering post-mortem examinations as a commercial service for privately owned equine, exotic and domestic animals.10.30 – 11.00Refreshments served in the Caernarfon Suite11.00 – 13.00WORKSHOPSW6 Confidence is key – details on page 62.W10 IAT Education End Point Assessors for Level 2 and 3 – details on page 66.W11 Using your smartphone – details on page 67.W12 The ‘Roadmap’ to refinement – details on page 68.Chair: Wendy Steel, Trustee, Animals in Science – Education TrustPAPER PRESENTATIONS11.00 – 11.30African clawed frog – diseases and clinical signsThis talk is a discussion about the various clinical signs that can affect Xenopus laevis frogs. It discusses the various diseases and adverse events that affected our colony at Cambridge University over a 3-year period and what we did to overcome them. It also has an aim to open up a dialogue about clinical signs and expand the material available for other technicians and researchers.Rue Jones-GreenChief Aquatic TechnicianUniversity of Cambridge Rue is a NACWO for The University of Cambridge. She has looked after Xenopus frogs and various other aquatic species and systems for over 15 years.

Scientific Programme4811.30 – 12.00Managing invertebrates for environmentally improved biopesticides It is well published that the neonicotinoids and other insecticides are killing non-target species such as pollinators and predators. They are also persisting in the environment where further toxicity occurs, such as to the aquatic environments. However, there are very few alternatives available and that is why these compounds are still used, as with a growing human population pesticides are needed for food security. Biopesticides such as peptides have the potential to be much less persistent in the environment as they are more likely to be broken down into harmless amino acids by detritivores and bacteria. A special group of peptides are those from venoms which have evolved to kill prey species quite specifically and thus are of particular interest. This presentation will describe husbandry techniques for a diverse range of species used in this work from slugs to bean weevils and a recap on new techniques with those providing the venoms. Techniques used both for biopesticide discovery and those of interest to invertebrate medicine will illuminate this talk with the aim of bringing new skills for invertebrate research. This talk will bring the delegates into the unusual world of invertebrates, including measuring slug heart rates, and update work from the Veterinary Invertebrate Society, with which the IAT has a partnership. Steven TrimFounder, Chief Scientific OfficerVenomtech Ltd Venomtech Ltd is a UK biotech company set up initially to provide assay ready venom fraction libraries for drug discovery. Steven started his drug discovery career with 10 years as a molecular biologist, biochemist and safety delegate at Pfizer global research and development, Sandwich. Steven took this in depth drug discovery expertise to solve a key problem, that of finding good, selective, ligands. He set up Venomtech in 2010 to do just that with the UK’s only commercial venom laboratory. He won the Andrew Blake Tribute Award for Animal Welfare by demonstrating tarantulas respond to environmental enrichment. He also had a patent granted for safe methods of feeding venomous snakes and one submitted for venom based pesticides. Steven received chartered biologist status from the Royal Society of Biology in 2016, is Chair of the Veterinary Invertebrate Society and an ELRIG committee member. Steven continues to lead the science at Venomtech and published several papers on venoms in drug discovery, invited book chapter for Progress in Medicinal Chemistry and Springer Nature ion channels.12.00 – 12.30Mary Lyon’s brilliant and illuminating conjecture A general finding in animals is that the correct dosage of genes is two, with one copy inherited from each parent. Deviation from this diploid condition typically leads either to abnormality or lethality. That in mammals the X-chromosome carries many genes that are absent from the much smaller male-determining Y-chromosome clearly seems to pose a dosage problem. One suggestion for addressing this was that genes on each X in females might be expressed at half the level of those on the single X in males. However, there was no obvious precedent for such a possibility.In 1961 Mary Lyon offered a most elegant solution to the problem in a paper in the journal Nature which was not only a model of clarity and brevity but has withstood the test of PAPER PRESENTATIONS AND MAIN PROGRAMME

Scientific Programme49PAPER PRESENTATIONS AND MAIN PROGRAMMEtime. She addressed the issue by making three deductions from just two observations in mice. Among other things, her conjecture offers a compelling explanation as to why females are much less susceptible to adverse effects of mutation of genes carried on the X-chromosome than males.Richard Gardner KBE FRS Richard Gardner studied Natural Sciences at St Catharine’s Cambridge before doing a PhD in the Physiological Laboratory with Bob Edwards. In 1973 he was appointed to a University Lectureship in Zoology at Oxford where, from 1978 until his retirement in 2008, he held a Royal Society Research Professorship. His research interests include investigating the lineage and patterning of cells in early mammalian development and the biology and properties of the various types of stem cells derived from early embryos.He was awarded the Zoological Society’s Scientific Medal in 1977 and elected to the Royal Society in 1979. He received the March of Dimes Prize in Developmental Biology in 1999, the Royal Society’s Royal Medal in 2001 and a Knighthood in 2005. He gave the British Fertility Society’s Patrick Steptoe Memorial Lecture in 2015 and was awarded the British Society for Developmental Biology’s Waddington Medal in 2018. For many years he chaired the Royal Society’s working group on ‘human embryo research’, and in 2006-8 served as President of the Institute of Biology (now the Royal Society of Biology). He is Past President of the IAT and Chair of the Board of Trustees for Animals in Science – Education Trust (AS-ET).12.30 – 13.00Development of a sifting cage change method for rats to improve welfareA year ago, I started work in the rat room in the Centre for Virus Research Unit (CVRU). I noticed the temperament of the rats could be skittish and aggressive and as a result, both staff and researchers were reluctant to interact with them. As rats are incredibly sensitive to their housing environment, I wondered if this could be having an impact and if so, maybe discover a way to improve their temperament. Could altering the way the cages were changed improve temperament? Over time, I have optimised a ‘sifting’ cage change method, which maintains more of the rat’s scent in the cage, whilst allowing for removal of faeces and soiled sizzle bed. This differs from the previous method of adding a handful of soiled bedding to a clean cage of bedding. Using the sifting method has had a noticeable effect on the behaviour of the rats. Research staff have confirmed the rats’ temperaments have improved; the rats are far less jumpy and calmer. As a result staff feel more confident when working with them.Seonagh HendersonSenior Animal Technician, CVRU University of Glasgow Seonagh is a senior Animal Technician within biological services at the University of Glasgow. She has worked there for nearly 19 years and over the last few years, implemented a new way of changing bedding in cages for rats to improve their welfare and reducing the environmental impact of this

Scientific Programme50PAPER PRESENTATIONS AND MAIN PROGRAMMEprocedure, as well as saving money for her department. This idea has been published as a Tech-2-Tech article in Animal Technology and Welfare (ATW), for NC3Rs’ 3Rs champion, won two awards through the University’s 3R’s day and the AS-ET prize for innovation.Seonagh is highly motivated to provide the best possible care to the animals that she looks after through an avid interest in Animal Welfare, science, and research. She has a love for all animals having worked with the biggest Clydesdale horses, to the smallest baby mice.13.00 – 14.000LUNCH – meals and refreshments served in the Caernafon SuiteChair: Penny Hawkins, Vice President, Institute of Animal TechnologyPAPER PRESENTATIONS14.00 – 14.30 An international survey on environmental enrichment for laboratory ZebrafishThe Zebrafish (Danio rerio) is one of the most commonly-used animals in scientific research and testing, both in the UK and worldwide, but best practice for many aspects of Zebrafish husbandry and care is still debated. One such area of discussion is the use of environmental enrichment - modifications which are made to the environments of captive animals with the aim of improving their welfare. Despite a growing body of evidence that suggests that enrichment can improve Zebrafish welfare, and wide acceptance of the importance of enrichment for other laboratory species, provision of enrichment for Zebrafish can vary between facilities and may be relatively minimal. To better understand which kinds of enrichment are most widely used for Zebrafish, and what the barriers are that prevent wider uptake and implementation, the RSPCA conducted an international survey of Zebrafish research facilities. Participants were asked about various aspects of the enrichment approaches used in their facilities, including types used, whether any forms of enrichment had been discontinued, and what challenges they faced in introducing more enrichment. Over 100 facilities from around the world responded to the survey. This talk will summarise the key results of the survey, and discuss how these results might be used to improve enrichment practices, as well as inform future advocacy work and improve communication of relevant information.Chloe StevensScientific OfficerAnimals in Science Department, RSPCA Chloe works on promoting refinements and better welfare for fish and other aquatic species used in research and testing. Her recent work has focussed on reviewing and disseminating the evidence for the effects of environmental enrichment on laboratory Zebrafish. Before joining the RSPCA in 2018, Chloe completed an MBiolSci in Biology at the University of Sheffield, followed by a PhD at the University of Exeter, in which she studied welfare, stress and mortality in ornamental fish species.

Scientific Programme51PAPER PRESENTATIONS AND MAIN PROGRAMME14.30 – 15.00Andrew Blake Tribute Award Winner 2023Box training as a refinement for rabbit trainingIn the wild rabbits are prey animals and so the act of being picked up and handled can be extremely stressful for them. Previous studies in pet rabbits have shown that the during the act of lifting, rabbits show signs of struggling and aggression due to fear. This is relevant to the rabbits we house in our facility and can cause unnecessary stress, which potentially will negatively affect the research they are being used for. In our case, the rabbits are cardiovascular models of Myocardial Infarction and so keeping stress levels down where possible is important. We investigated a new method of handling our rabbits which involved training the rabbits to jump into an animal carrier to be transported to their destination; either a playpen or scales multiple times a week. The carrier was lined with either a vetbed that was shared amongst their group, or a vetbed that was not shared and was only given to the individual rabbit. The rabbits were timed how long they took to jump into the box with a limit of 3 minutes. The vetbed is a positive incentive we trialled for them to jump into the box and we found that the shared vetbed was preferred due the desire to investigate the different smells left by the other rabbits when it was presented to them. During the study we found that the rabbits who had undergone surgery during the time they were monitored were less likely to jump into the box during their 3-day post op period and so were carefully carried when required.Alicia KinallyDivision of Biomedical ServicesUniversity of Leicester Further details on page 12.ANDREW BLAKETRIBUTE AWARDThe Andrew Blake Tribute Award is generously sponsored by the Association of British Pharmaceutical Industries

Scientific Programme5215.00 – 15.30AAALAC Fellowship WinnerEvolution of a large, complex, decentralised, academic animal care programmeProviding consistent levels of excellent service, animal care and regulatory compliance can be exceptionally challenging at large, decentralised animal research institutions. The 61 years since the University of Michigan established an organised animal care programme, including veterinary specialty training, have witnessed waves of evolution. Especially within the past ten years, significant culture change has necessitated enhanced communication and provided opportunities for partnership. This presentation will review the University of Michigan’s history and outline the metrics and strategies utilised for our transformation, as well as current initiatives and goals for the programme. As in any organisation, the key to progress is enabling personnel to provide input and work collectively. The University formed new teams with shared visions and overlapping responsibilities to achieve unified programmatic advancement. This involved creation of several new positions and the development of a system of self-assessment to identify areas of opportunity and measures of success. Valerie Hill,Chief Department Administrator/Director Campus Animal Care University of Michigan Further details on page 19.15.30 – 16.00Refreshments served in the Foyer – Caernarfon Suite15.30 – 16.00MEET THE POSTER AUTHORS – Foyer, Caernarfon Suite, Level C1Chair: Linda Horan, CEO and Chair, Institute of Animal Technology16.00 – 17.00KEVIN DOLAN MEMORIAL LECTUREA glimpse into the weird and wonderful world of ARTDetails on pages 54 and 55.Session sponsored by IPSPAPER PRESENTATIONS AND MAIN PROGRAMME

Scientific Programme53AWARDS CEREMONY AND MAIN PROGRAMME17.00PRIZES AND AWARDS FOLLOWED BY CLOSE OF CONGRESSBEST POSTER PRIZESfor Animal Welfare and Scientific Basis Sponsored by LBSABTA 2023Sponsored by The Association of the British Pharmaceutical IndustryJournal Article Award 2022 – Animal Technology and Welfare Journal Marjorie (Sandiford) Whittingham Memorial PrizeSponsored by Institute of Animal TechnologyAAALAC International USA Fellowship Award 2023Congress will be officially closed byLinda HoranCEO and Chair Institute of Animal Technology

54 Scientific Programme Assisted Reproductive Technology (ART) is the term commonly applied to technology that is used as an intervention for procreation both in humans and animals.This includes fertility treatments in which either sperm, eggs or embryos are handled, but the term can also be extended to cover the rapidly expanding development and application of more advanced techniques such as sperm sexing, cloning, pre-implantation genetic testing and gene editing, to name a few.Based on the personal experiences of someone who has (often unwittingly) been involved with many of these emerging technologies, this presentation aims to present a light-hearted, honest and pragmatic view of where things currently stand with regards to commercial breeding programmes, conservation, and the treatment of infertility.This will include an account of some trials and tribulations and a couple of examples of what happens when things go wrong!A GLIMPSE INTO THE WEIRD AND WONDERFUL WORLD OF ARTKevin Dolan 1926 - 2011When Kevin Dolan died in 2011 at the age of 85, IAT Council wished to honour his memory in gratitude for the contribution he had made to Animal Technologists and the industry in general and therefore fittingly, the Special Guest Lecture given annually at Congress was renamed the Kevin Dolan Memorial Lecture.Kevin’s contributions to the IAT included services on Council and for several years he was Editor of the IAT Journal, only standing down on his retirement. He received his Fellowship in 1977 at the same time as attaining a Diploma in Law. He was also made a Vice President of the IAT and latterly an Honorary Member.KEVIN DOLAN MEMORIAL LECTURE

Scientific Programme 55He also authored many distinguished books and articles on the subject of law and ethics using animals in science but it was as a teacher that Kevin had most impact. He taught on the Postgraduate Diploma/MSc course, the Medical Technology courses at City of Westminster and on Personal Licence Modular training courses. To paraphrase one of his students ‘Kevin was a great teacher because he was passionate about the subject he was dealing with and the people he was teaching to’.Despite joining the world of animal technology somewhat later in life after many years in the ecclesiastical domain, Kevin’s impact on our industry was outstanding. His was a life well lived in the service of others and in recognition is remembered at Congress.MATT PETTIT BScHead of Innovation and Product Expert, IMT International LtdIn 2005, Matt joined IMT as General Manager responsible for development and implementation of ‘Matcher’, an electronic witnessing and quality management system, and for the development of novel cryopreservation technologies and associated protocols. Since gaining a degree in Biology at the University of Wales in 1990, he has worked in the field of Assisted Reproductive Technology, including roles managing laboratories, R&D and quality control at the UK’s leading bovine breeding companies and cryo-storage facilities.Matt’s primary focus is now on developing simple-to-implement, practical solutions to error prevention, traceability and cryo-stores management in human IVF clinics and donor banks. This role involves designing systems that can be easily fitted around clinics’ existing SOPs and advising clinics on the validation required for such automated systems.Matt is also a trustee of a charity called Nature’s SAFE which is on a mission to help save animals from extinction by collecting, indefinitely storing and regenerating reproductive cells and cell lines from endangered animal species.

Scientific Programme56CPD WORKSHOP SESSIONS4 CPDPOINTSWORKSHOP 1A practical viewpoint of working with Home Cage Monitoring systemsThe use of Home Cage Monitoring (HCM) is growing in the field of biomedical research and these systems are showing their value in terms of objective measurements of animal activity and behaviour leading to increasingly robust scientific results. The publications and presentations often focus on the scientific outcomes and the monitoring of the animals by the technology. This workshop will include interactive short presentations to generate discussions about the practical use of HCM systems with two focusses: (1) how we need to adapt our working regimes to suit the monitoring system and (2) how we can adapt the system to suit our needs. We will look at a broad range of systems used for monitoring animals across a continuous 24-hour period. We will discuss how we can still maintain the welfare observations and practical care of the animals and what to consider when placing cameras or animals in these environments. We will highlight and discuss the European Cooperation in Technology (COST) action called TEATIME. This is a consortium which brings together researchers across Europe to investigate the best ways of using HCM to refine how animal research is performed using automated behaviour monitoring in the animal home-cage. We want to highlight how TEATIME can help technicians who want to learn how to use the systems as well as work in rooms where the systems are used. We will finish by discussing horizon scanning for other systems and how we could build a network of technicians who work with them.Tuesday 21st March 14.00 – 16.00 Denbigh Room 1Joanna MooreInvestigator and NIO, Laboratory Animal MedicineGSKSara WellsScientific Manager Medical Research CouncilJoanna has worked with laboratory animals for over 25 years in a range of roles across different sectors. She has always had a strong focus on welfare and enrichment. In 2018 she was awarded a PhD in Animal Sciences. More recently, Joanna has been working with Home Cage Monitoring primarily with the Digital Ventilated Cage system and remote cameras, to utilise the capabilities of these systems as scientific, husbandry and welfare tools for mice.Sara is the Director of the Mary Lyon Centre at MRC Harwell. In her role she oversees and coordinates mouse genetics projects and animal welfare. Sara is driven by the continually changing field of genetics, its advancements and challenges. Sara is keen to promote technological opportunities which promise to be able to reduce and refine the work undertaken in animal research.

Scientific Programme57CPD WORKSHOP SESSIONS4 CPDPOINTSTuesday 21st March 14.00 – 16.00 Conwy Room 2WORKSHOP 2Preparing to present for the first timeThis workshop is tailored towards those who would like to present at a meeting but never have. Barriers to giving a presentation include fear of public speaking; not knowing what to talk about, or how to talk about it. Topics covered in this interactive session will include choosing a topic, the preparation process, knowing your audience, explaining tough concepts, and giving the talk itself. How adults learn and exercises to overcome nervousness will also be incorporated. Attendees will ideally come prepared with an initial idea of a topic on which they would like to create a presentation and this session will provide the framework to allow them to go out and speak with success.Diana BaumannHead of Reptile and Aquatics FacilityStowers Institute, USADiana has worked at the Stowers Institute in Kansas City, Missouri since 2003. She regularly speaks at National and International meetings and teaches technician and management certification courses. She has served on three AALAS committees, is a member of the Laboratory Animal Management Association education committee, and President of the Australia New Zealand Association of Aquarium Professionals. Diana serves as an ad hoc specialist for AAALAC International. She has published and presented on a diversity of topics and is the recipient of multiple awards for teaching, management and contributions to the field.

Scientific Programme58CPD WORKSHOP SESSIONS4 CPDPOINTSWORKSHOP 3Refining wound closure using intradermal stitches – a practical learning lessonAimed at Animal Technicians of all levels of skill and experience, this workshop focusses on providing practical experience in the use of intradermal sutures as a refinement during wound closure. The pros and cons of different wound closure methods will first be introduced, with the majority of time then spent learning how to place intradermal sutures. The aim of this workshop is to provide attendees with enough information and experience in intradermal suturing that they have the confidence to trial it themselves in-house. For those with limited experience of suturing, some time will be spent first learning the basic techniques.Tuesday 21st March 14.00 – 16.00 Conwy Room 1Emma StringerAssistant Director, Biomedical Services UnitUniversity of BirminghamSarah BleakleyNamed Veterinary Surgeon University of BirminghamEmma obtained her undergraduate degree in Bioveterinary Science from the University of Liverpool in 2004. She then went on to complete her PhD in Biochemistry at the University of Leicester in 2008 before moving into the field of cardiovascular science as a Research Fellow where she led a programme of research using genetically altered mouse models to investigate the role of a number of candidate genes in the development of coronary artery disease. In 2016 Emma joined the NC3Rs as Regional Programme Manager (Midlands) where she obtained expertise in identifying and applying 3Rs-related methods, before becoming Assistant Director of the Biomedical Services Unit at the University of Birmingham in 2020, with a particular focus on the 3Rs.Sarah achieved a degree in Veterinary Medicine from the University of Cambridge in 2015 after an intercalation year studying Zoology. She initially worked in mixed practice, working with farm, equine and small animal patients. She completed her Named Veterinary Surgeon qualification in 2019 and now does a mixture of small animal clinical work, exports and NVS work, primarily with the University of Birmingham. She is currently undertaking a masters in anaesthesia and analgesia with the University of Edinburgh and has a particular interest in applying the techniques used in current clinical practice to help refine our approaches in a research setting.

Scientific Programme59CPD WORKSHOP SESSIONS4 CPDPOINTSTuesday 21st March 14.00 – 16.00 Conwy Room 1Claire OnionsSenior Animal TechnicianUniversity of BirminghamClaire joined the Biomedical Services Unit at the University of Birmingham as a junior Animal Technician in 2004. She was promoted to Senior Animal Technician in 2016 and since then has developed a particular interest and skill in providing support during surgical procedures. Claire has worked closely with the Named Veterinary Surgeons to embed intradermal suturing as a routine method of wound closure used in the unit. Claire has since become a trainer in this technique, training both technicians and researchers alike.

CPD WORKSHOP SESSIONS60 Scientific Programme4 CPDPOINTSTuesday 21st March 14.00 – 16.00 Denbigh Room 2WORKSHOP 4Focus on aquatic animals: current issues in regulation, ethics and welfareIt is widely recognised that the use of fish in scientific research is increasing and many other aquatic organisms, including amphibians, cephalopods and decapod crustaceans are also regularly used in scientific research. However our perceptions of, and attitudes towards, these animals tend to differ when compared with other common research animal species, such as rats and mice. Similarly knowledge and understanding of good practice for housing, husbandry and care of aquatic animals tends to lag behind mammalian species. In this workshop, we will discuss how and why attitudes towards aquatic animals might differ from those towards other animals and how this may affect how we use them in laboratory settings. We will consider current issues relating to regulation, ethics and welfare for aquatic animals in this context and participants will be encouraged to reflect on their own perceptions, opinions and uses of these animals.Chloe StevensScientific Officer, Animals in Science DepartmentRSPCAChloe works on promoting refinements and better welfare for fish and other aquatic species used in research and testing. Her recent work has focussed on reviewing and disseminating the evidence for the effects of environmental enrichment on laboratory Zebrafish. Before joining the RSPCA in 2018, Chloe completed an MBiolSci in Biology at the University of Sheffield, followed by a PhD at the University of Exeter, in which she studied welfare, stress and mortality in ornamental fish species.

Scientific Programme61CPD WORKSHOP SESSIONSWORKSHOP 5The principles of IVCsThis workshop focusses on the principles of IVCs, why we use them and how they optimise animal health and welfare. Topics covered:l key concepts of IVCsl animal health and welfarel technician safetyl environmental consistencyl IVC equipment features and functionsl optimal working practicesThe workshop format is interactive and uses andragogic teaching approaches to maximise learner participation and outcomes. The workshop is presented in bitesize topic related sections with video, animations, question and answers.A detailed Resource Pack is provided to support the learning undertaken.- Recognises the causes of work-related illness in animal technicians and demonstrate knowledge of working practices to avoid them.- Describes how environmental consistency impacts animal health and welfare and science quality and demonstrates the checks needed to maintain it.- Explains undertaking safe and effective working practices with IVC equipment to optimise its benefits.- Explains what IVC equipment achieves and how it functions.- Explains the importance of animal health and welfare and recognise the measures we take to protect and maintain it.- States causes of ill health in animals, understanding the protective barriers put in place and identify how IVC equipment fits into this strategy.Carl BreackerIVC and Aquatics Product ManagerTecniplast UKCarl has been in the Animal Technology sector for 15 years and has worked in both contract research and academia. During his 10 years in academia, Carl was a NACWO and oversaw the aquatic facility, working with a number of species, including mice, rats, rabbits, guinea pigs, desert locusts and a variety of aquatic species. Carl joined Tecniplast in September 2019 and is the Product Manager for the Tecniplast portfolio including housing, biocontainment/bio exclusion, aquatics, laminar flow and allergen control. Along with managing the products, he provides technical support to the Tecniplast account managers, facilities, researchers, project managers and architects.4 CPDPOINTSWednesday 22nd March 11.00 – 13.00 Denbigh Room 1

62CPD WORKSHOP SESSIONSScientific ProgrammeWORKSHOP 6Confidence is key: evaluating environmental enrichment for improved Animal WelfareWhen trying a new form of environmental enrichment, or reviewing what is currently provided, assessing whether it improves Animal Welfare is a vital part of the process. Evaluations of environmental enrichment allow us to make confident, welfare-focussed decisions. However overcoming the challenges of assessing enrichment within a research setting, and knowing where to start, can be intimidating. This interactive session will draw upon practical resources created by the NC3Rs in collaboration with the RSPCA and the IAT. Together we will cover the process of an evaluation including the importance of considering the natural behaviour of animals, how to ask animals what they want and ways to improve the reliability of your findings. This workshop is suitable for Animal Technicians who are new to evaluating enrichment and those with more experience who want to make improvements to their current approach. Join us if you want to have increased confidence that the environmental enrichment that you provide to your animals is improving their welfare.Khia DobbinsonScience Manager, Animal WelfareNC3RsLaura McKillopRegional Programme ManagerNC3RsKhia’s background is in zoology and animal behaviour. She creates practical online resources aimed at Animal Technicians, provides 3Rs guidance through the NC3Rs peer review and advice service and produces Tech3Rs (the NC3Rs’ newsletter for Animal Technicians.)Laura’s research career has spanned the biomedical sciences with particular interests in physiology and neuroscience. As a Regional Programme Manager at the NC3Rs, she promotes the 3Rs and provides dedicated local support for their implementation at King’s College London and the Francis Crick Institute. This includes providing expert advice and coordinating the sharing of good practice. She is a member of the Policy and Outreach Group.4 CPDPOINTSWednesday 22nd March 11.00 – 13.00 Denbigh Room 2AndThursday 23rd March 11.00 – 13.00 Conwy Room 2

Scientific Programme63CPD WORKSHOP SESSIONS4 CPDPOINTSWednesday 22nd March 11.00 – 13.00 Conwy Room 1WORKSHOP 7Lessons from a Meerkat – tips and tricks to engage your traineesA practical in-person workshop to complement online training for trainers and assessors at Newcastle University. Developed by the Newcastle NTCO team and delivered by a specialised team of procedural technicians this ‘out-of-the-unit’ workshop reinforces training techniques and covers aspects such as what makes a good trainer, structuring your training sessions and how to troubleshoot as well as introducing some top tips for tricky situations.Terri-Anne BadcockProcedural Technician, Comparative Biology CentreNewcastle UniversityDemi MinhinnettProcedural Technician, Comparative Biology CentreNewcastle UniversitySince starting as a junior Animal Technician in 2013, Terri-Anne has worked with various different species in numerous different facilities, her favourite species still being rats even though she love them all! After recently acquiring a Procedural Technician role at Newcastle, Terri-Anne’s focus has largely changed to training and competency, which has involved the rollout of a training management process, a practical training workshop and participating in an audit to ensure all current PIL holders feel competent and supported in the skills they conduct. In addition to this, she also has a keen interest in rodent colony management.Demi began her career in 2016 as an Apprentice Animal Technician at Durham University, working with mice, rats, rabbits, Zebrafish and xenopus on research including monoclonal and polyclonal antibody production, behavioural and biological research. After 3 years at Durham University, she obtained a position at Newcastle University as an Animal Technician and was able to work with new species including starlings, chickens and primates. More recently Demi became a Procedural Technician working within the training and competency team, with a focus on ensuring high quality training is provided and competencies are gained and maintained, alongside teaching duties and supporting procedural and husbandry work.

Scientific Programme64CPD WORKSHOP SESSIONSWORKSHOP 8Catheter Patency Strategies During SurgeryCatheter patency strategies during surgery play an important role in the reduction of animal use. Animal drop out due to blocked catheters is a commonly reported problem in so called (chronic) freely moving blood sampling models. Acute blood sampling techniques such as sphenic vein puncture are not always suited; in this case the restraint for obtaining blood compromises the endogenous ‘true’ value of norepinephrine in rats. Many factors during surgery have impact on the formation of thrombi post-operatively and subsequent catheter patency. Recognising these factors and optimising surgical procedures can further contribute to the reduction of animal use and the quality of stress research (true value of stress hormones). A case study is presented where blood sampling methodology and optimising surgery play in important role in reduction of animal use in stress research.Edwin Spoelstra Business Development ManagerUNO BVEdwin brings with him over 25 years of experience at the interface of biotechnology and sales. Edwin earned an MSc in Neurochemistry and Molecular Pharmacology at University of Groningen in 2000. Following his degree, he continued researching CNS animal models and stereotaxic surgery for intra-cerebral microdialysis. With his expertise and understanding of the needs of research scientists, Edwin has successfully supported customers at life-science companies including Dilab, Instech Solomon, Harlan, TSE Systems, BASi, SAI-Infusion and now UNO – Life Science Solutions. He is actively engaged in teaching techniques and ethics in experimental surgery on rodents, and advocates for ethical surgical and laboratory practice.4 CPDPOINTSWednesday 22nd March 11.00 – 13.00 Conwy Room 2

Scientific Programme65CPD WORKSHOP SESSIONS4 CPDPOINTSWORKSHOP 9Speaking upWhy is it so hard to talk about animal research and what can we do about it?This interactive workshop will help you communicate better about animal research and feel more confident in work and social situations. We will look at techniques for debate and rebuttal, how to answer the trickier questions and offer tools for dealing with challenges and confrontation.John MeredithHead of Education and OutreachUARJohn works with young people in classrooms across the UK to help them better understand animal research and provides support and training in communications and outreach for scientists and Animal Technicians. He previously developed educational programmes and materials for a wide range of clients including the Army, BT and Marks and Spencer and was an educational adviser to the Commission for Architecture and the Built Environment.Wednesday 22nd March 14.00 – 16.00 Conwy Room 1

Scientific Programme66CPD WORKSHOP SESSIONSWORKSHOP 10IAT EducationIAT Education are the End Point Assessment organisation for Level 2 and 3 apprenticeships. We will look at these apprenticeships’ standards and discuss how to get the best from the apprentice in the workplace and the challenges we faced during the pandemic as End Point Assessors (EPA).The workshop will include breakout groups, a mock grading of an apprentice case study and a practical assessment. In groups we will ask you to assess your apprentice using the grading criteria within the apprenticeship standards.Tina O’MahonyChair of Board of AssessorsIAT EducationTheresa LangfordEnd Point AssessorIAT EducationTina has been involved with animal research since 1990. During that time she has worked with multiple species, now primarily with genetically altered rodents. Tina is the NTCO, NACWO and Operations manager at the Sainsbury Wellcome Centre in London. She is a RAnTech and an IAT Council Member. Tina is currently the IAT Education Chair of Board of Assessors for apprentices within the animal care sector.Theresa worked for over 40 years in the field of Laboratory Animal Technology, primarily with genetically altered mice. She has been involved in animal facility design, commissioning and facility management. During this time, Theresa worked with unusual species and provision of bespoke accommodation. She is a RAnTech panel member and member of IAT Council.Theresa is now an End Point Assessor for Apprentices within the animal care sector.4 CPDPOINTSWednesday 22nd March 14.00 – 16.00 Conwy Room 2AndThursday 23rd March 11.00 – 13.00 Denbigh Room 1

Scientific Programme67CPD WORKSHOP SESSIONS4 CPDPOINTSWednesday 22nd March 14.00 – 16.00 Denbigh Room 1AndThursday 23rd March 11.00 – 13.00 Denbigh Room 2WORKSHOP 11Using your smartphone to film your workThe phone in your pocket can take broadcast quality video. In this workshop we show you how to tweak your phones settings and then use it to take high quality images and video clips.The material you record can be used in training, recording unique experimental set-ups and in communicating about our work. We will show you examples of all three. The workshop will be presented by Richard Scrase who makes the videos and Mary Harvie who makes the infographic content and manages the social media channels on the UAR websites.Richard ScraseHead of Online CommunicationUARMary HarvieDigital Communications ManagerUARRichard manages UAR’s online presence and makes the most of the UAR videos. He switched over from science teaching into science communication with the help of the Science Media Production MSc taken at Imperial College around 20 years ago.He then worked as a freelance science producer before joining UAR in 2010.Mary joined UAR in 2016 after studying for a BSc in Animal Behaviour and Welfare. She has a background in animal care and welfare and spent 6 years working in the Pets and Aquatics industry. Mary has had a few roles at UAR, originally working with members in Animal Technology to develop their social media and websites, foster openness and improve Animal Welfare through the promotion of continuous professional development (CPD) for Animal Technologists and researchers. She is now responsible for everything social media and creates the content for UAR’s Facebook, Twitter, LinkedIn and Instagram accounts. Mary also maintains UAR’s websites.

Scientific Programme68CPD WORKSHOP SESSIONSWORKSHOP 12The ‘Roadmap’ to refinementEvery animal used in research experiences multiple events during their lifetime. These may include not only scientific procedures but also transport, marking for identification, capture, handling, restraint, laboratory housing and husbandry and humane killing. Some events can be anxiety-inducing, painful or distressing, which can affect the animal’s ability to cope with experimental procedures.In this interactive workshop we will use the ‘Roadmap’ approach to help understand animals’ lifetime experiences and predict cumulative effects, within all severity categories. You can use it as an individual, or as a member of a refinement or user group, or when sitting on an Animal Welfare and Ethical Review Body (AWERB). As Animal Technologists, your expertise can contribute significantly to identifying, implementing and evaluating refinements, as well as to effective prospective and retrospective severity assessment. The workshop aims to provide you with a new tool to help with all of the above tasks.Penny HawkinsHead, Animals in Science DepartmentRSPCAPenny is Head of the RSPCA Animals in Science Department, which works to achieve more effective ethical review of animal use and further the implementation of the Three Rs. She joined the RSPCA 26 years ago and has served two terms as a member of the Animal Procedures Committee and one on the Animals in Science Committee. Penny’s main areas of work relate to promoting effective AWERBs and also to refinement, for example reducing severe suffering; improving housing and care; assessing welfare; the use of animals in fundamental physiology research; telemetry; and humane killing. She is also the RSPCA’s scientific lead on animal sentience and gene editing farmed animals and one of the IAT’s Vice Presidents.4 CPDPOINTSWednesday 22nd March 14.00 – 16.00 Denbigh Room 2AndThursday 23rd March 11.00 – 13.00 Conwy Room 1

Scientific Programme69Sylvie has worked in this industry for 28 years starting at University College Cork, then moving to Trinity College Dublin in 2001. In 2018, she became Chief Technician at UCD. As well as a keen interest in Animal Welfare and environmental enrichment, she is also involved in both the Ethics and Animal Welfare committees and education. With an honours degree in animal science and technology, a master’s in management, RAnTech and FIAT, Sylvie ardently encourages members to continue their education. She is Chair of the IAT Irish Branch and involved in running their annual symposium. She is also a member of IAT Council, as she feels it is important that there is Irish representation. In 2015, Sylvie was the recipient of the AAALAC International Fellowship Award.John has worked in the animal research facility in UCD for the past 30 years. Currently he is the Animal Care and Welfare Officer (ACWO), an active member of the Animal Welfare Body and was a member of the Ethics Committee.He completed his IAT Level 3 in 2020 and over the last 30 years has attended IAT Congress, IAT Irish Branch symposiums and 3Rs workshops. When John joined UCD in 1992, he was working with farm animals but over the past number of years he has worked with rodents, predominantly rats. John has always had a keen interest in improving Animal Welfare and environmental enrichment. Over the past 3 years UCD Biomedical Facility has developed a programme to refine training, enrichment and Culture of Care for all of their animals. In doing so, John has contributed to the research community, welfare of the animals and welfare of the staff.SYLVIE MEHIGANChief Technician Officer 1University College DublinJOHN HOBBSAnimal TechnologistUniversity College DublinThe 3Hs: home, hammocks and happiness Our programme of environmental enrichment for animals and staff - how it is impacting on our shared environment, welfare and daily lives.At the UCD Biomedical Facility we always strive to improve our animals’ welfare and their environment. As part of this, in 2019 we started a programme to enrich their lives and promote a Culture of Care and continued implementation of the 3Rs.It is our mission to continue to improve the environment and enrichment of all animals in our care. We continue to find better ways to interact with animals daily. To this end we started a programme to aid our animals and give them a better life and to aid research and all those who work with animals in our facility. We commenced with handling tunnels, so when animals are being moved from their cages for any reason they are not handled by their tails. In 2019 we looked at other items we could use - this is where hammocks came in. We started with a small sample of rats and mice cages to see how they would interact with them. We continued our programme with habituation (rats and mice) tickling and playpens (rats) with great success.POSTER PRESENTATION

Scientific Programme70POSTER DISPLAYSLORNA CLEVERLEYFera ScienceEfficacy of chlorine gas for the destruction of Syphacia muris eggsPinworm nematodes, Syphacia muris, Syphacia obvelata and Aspiculuris tetraptera are commonly encountered in bioresearch facilities infecting laboratory rodents. They are notoriously difficult to eradicate due to their ability to aerosolise and contaminate a wide variety of environments. The availability of disinfectants to successfully eradicate pinworms from the environment is limited to potent phenolic compounds such as Neopredisan and traditional disinfectants such as Formaldehyde and ethylene oxide, both limited in their use due to flammability and carcinogenic properties. Chlorine dioxide gas is a powerful oxidant with excellent anti-microbial activity against a variety of micro-organisms including viruses, bacteria and parasites. It is considered an environmentally friendly safe disinfectant. We undertook a small study to determine the efficacy of Chlorine dioxide gas against eggs of the nematode Syphacia muris. Viable eggs were harvested and exposed to Chlorine dioxide at two different concentrations and time points resulting in 100% kill of Syphacia muris eggs.

Scientific ProgrammePOSTER DISPLAYS71KARLA ESPARAZACharles RiverMoving away from soiled bedding sentinelsThe use of laboratory rodents in biomedical research continues to be essential; ensuring the health status of these animals has become a key priority for facilities across the globe. Rodent health screening makes a fundamental contribution to research by monitoring the presence of infectious agents that can compromise the animal’s health and become a confounding factor. The history of rodent pathogen control goes hand in hand with the advancements in rodent husbandry, laboratory animal science and the overall development of new diagnostic methods. Traditional monitoring systems consisted of the use of Soiled Bedding Sentinels (SBSs i.e. animals exposed to dirty bedding from colony animals) tested using conventional diagnostic methods which required the euthanasia of SBSs. For many years, it was believed that SBSs were accurate representatives of the health status of colony animals. However recent studies have demonstrated that a reasonable number of pathogens and parasites are not well transmitted to SBSs, especially when rodents are housed in Individually Ventilated Cages (IVCs). In the last decade, researchers have proposed alternative methods to monitor the health status of rodent colonies which include the collection of samples from colony animals, environment, exhaust air dust (EAD) and more recently, soiled bedding via contact media. In addition, the development of molecular diagnostic assays such as Polymerase Chain Reaction (PCR) provides extremely sensitive and specific methods to evaluate the current infection status of animals. The combination of sentinel-free methods with molecular diagnostic tools can be a suitable solution for the replacement and refinement of rodent health screening, an option worth exploring for many facilities worldwide.AMY VENESSSainsbury Wellcome CentreMinimising aggression in CD1 and CD1 background mice with different enrichment typesIt is well known that CD1 male mice can show aggressive tendencies towards their cage mates. At the Sainsbury Wellcome Centre, we used different types of environmental enrichment to try to minimise aggression and the chance of animals having to be singularly housed, thus improving Animal Welfare. This poster will explore the findings.

Scientific Programme72POSTER DISPLAYSROSIE SMITH-LANGRIDGEAnimal Plant and Health Agency(APHA)JOSIE DUBBERAnimal Plant and Health Agency(APHA)Class 3 containment enrichment for cattleDoes positive reinforcement training, early habituation and socialisation decrease Duroc pig stress levels during blood sampling and restraint?The study investigated environmental enrichment interaction for cattle whilst in a Containment Level 3 (CL3) facility. This involved rotating different enrichment objects over a 3-week period and observing preferences to the different objects over time. Developing the study, I worked with an in-house biostatistician to work out required sampling frequency and how best to power the study, returning interesting results that would be great to share with the research community. Pigs kept in laboratory settings are often exposed to increased handling and procedural work. A large majority of research on this topic focusses on minipigs and lack of focus on commercial breeds. At APHA we use much larger breeds of pigs such as the Duroc or the British White Landrace cross. Clicker training and luring was used to train four female Durocs housed at an animal facility at APHA. Early habituation and socialisation techniques were also used in the first few weeks after the pigs arrived. Compliance levels were much higher than previous ‘long term’ pigs when being moved, trained, sampled, or interacted with in general. Sampling sessions were noted to be quicker and stress levels decreased due to the Duroc’s willingness to participate. This was in comparison to previous White Landrace cross’s and Durocs we have used for blood sampling who received less training, socialisation, and habituation. This suggests early habituation and socialisation combined with regular training decreases stress.

Scientific Programme73POSTER DISPLAYSMELISSA HEWSONAnimal Plant and Health Agency(APHA)JAMIE TUCKLabcorp Early DevelopmentLaboratories LimitedAn exploratory view into fat necrosis in miceDevelopment of restraint for non-human primates during inhalation dosingFat necrosis is a condition found in a variety of species including mice. It can often present itself as an intra-abdominal mass after pancreatitis, trauma, or abdominal surgery and can affect different areas within the abdominal cavity. In our mouse colonies, we have mostly seen fat necrosis affecting fatty tissue surrounding the uterine horns. The mice affected are female TgSHPXIG mice, a transgenic line bred, maintained and intracerebrally inoculated for prion disease studies.With ongoing monitoring and weighing we have observed clinical signs of fat necrosis, which include weight loss, sunken sides, and gradual disinterest in food. Through a post-mortem examination, we have also seen what areas are affected by this. Investigations are still ongoing to help determine the cause of identified fat necrosis in our TgSHPXIG mouse line. This includes ongoing sample collection of affected tissues and organs and observation of clinical signs.The aim of the poster is to show the changes that have been made to our inhalation masks with different shapes and sizes and what we are looking at for the future. Also, how we secure them to the animal’s face, the different types of material we have used and the addition of a device to hold the tubes and mask from above the animal reducing the mask and head being pulled downwards.The changes to the restraint chair are shown from our initial basic model where limbs needed to be held or restrained through to our newest design which promotes the hopeful use of the chair without requirements to have the animal’s limbs restrained and allowing for a more natural sitting position.

Scientific Programme74POSTER DISPLAYSBILLY MATTHEWSThe Pirbright InstitutePENNY IVESUniversity of ManchesterCooped up: refinement of a Gallus gallus domesticus environmentTo wheel or not to wheel?At The Pirbright Institute, we undertake infectious disease research using various animal models including chickens. Animal Technicians play a vital role in implementing the 3Rs, in particular refinement, to the way the animals are housed. Poultry have unique housing and husbandry requirements and this poster outlines some of the advances made in this area. Central to housing poultry, multiple iterations of a raised floor pen design have been implemented. Environmental conditions such as temperature, humidity and lighting have also been refined. A wide variety of enrichment, both food and non-food, are also offered daily on a rotational basis. The result has been to maximise the expression of normal behaviours in the poultry house at The Pirbright Institute, as well as an observed reduction in feather pecking. The implementations of these enrichment factors are of benefit to the wider industry and the continuation of using healthy birds in research.A study at the BSF Stopford Building looked into the implementation of running wheels in overweight prone strains of mice and the integration of this practice into mouse protocols. The aim of this project is to monitor the health and welfare of overweight laboratory mice in order to induce exercise and enhance animal enrichment whilst reducing obesity. We catalogued the weight, food and water consumption of all mice involved (both in the cages with wheels and in the control cages without wheels). Collected data has been analysed with the use of graphs and statistics. This study implements the 3Rs by determining if the use of wheels is beneficial to laboratory mice. HypothesisH1 - Cages with the implementation of running wheels will have significant weight difference in comparison to the control cages. Null - Cages with the implementation of running wheels will not have a significant weight difference in comparison to the control cages.

Scientific Programme75POSTER DISPLAYSDAVE BLACKUniversity of EdinburghVICKY WALCZAC-GILLIESUniversity of EdinburghCare through training: how training can benefit the Culture of CareRefining the welfare of immune compromised mice receiving CCl4 to induce liver fibrosisThis poster will demonstrate how training staff to a high standard has benefits not only for the animals but also technical staff, researchers and students with regard to a Culture of Care. The work will highlight the University of Edinburgh (specifically BVS) training team duties, goals and remit. It will focus on the benefits to the animals and also include examples of the benefits, such as skill retention, reduction in administration time and how technical staff benefit from this in their daily routines.Immune compromised mice are highly susceptible to pathogens due to their immune system lacking certain cells. With this in mind the way we treat and care for them has to be slightly different.Within Resolution Therapeutics we have adapted the care and welfare routine for the animals we use to provide them with the best care possible and to pick up any possible problems early, meaning we can intervene to reduce any suffering that the mouse may be experiencing.CCl4 is a highly toxic substance but used at a low dose will cause the mouse to develop fibrosis in the liver, which then means that new therapies can be tested to see if they work on the fibrosis. This poster will aim to point out the different techniques used within our group meaning we have more animals reaching the scientific end point rather than reaching a humane end point and having to be removed from the study. Refining the methodologies improves both animal welfare and scientific outputs, which in turn reduces the need to repeat studies and the overall number of animals required.

Scientific Programme76POSTER DISPLAYSJILLENE VISSERNuclear Medical Research InstituteSouth AfricaAnaesthetics that complement radiotracer PET/CT imaging in rodentsImaging techniques such as Positron Emission Tomography (PET) / Computed Tomography (CT) provide the means for studying physiological and pharmacological processes in vivo in animals and humans as they occur in real time. PET/CT imaging is utilised in all branches of pharmacology, molecular biology and medicine, including neuroscience, cancer, inflammation and cardiovascular research. In the pre-clinical setting, rodent animal models are commonly anaesthetised with ketamine or isoflurane in order to prevent movement during the imaging procedure that causes image acquisition artefacts. However, the use of anaesthesia in PET/CT studies often alters the physiological mechanisms within the rodents and as a result, the PET/CT findings obtained in anaesthetised animals may fail to represent accurate physiological properties. The aim is to review findings of rodents anaesthetised with different anaesthetics and administered with common radiotracers for PET/CT imaging studies to provide information that can enhance the non-invasive representation of physiological processes in rodents and lead to an improvement in PET/CT imaging quality.MARIE HITCHAMCancer Research UKRats and the 3Rs: introducing best practice and refining rat welfare in a research settingThe freedom to express natural behaviour is essential in ensuring the welfare and wellbeing of laboratory animals. We have spent the last 12 months investigating enrichment techniques for rat welfare to enhance the lives of our research animals. We have learned that using a ‘Playpen’, new enrichment pieces and introducing tickling to our rat colony has brought numerous positive aspects to the science and animal welfare as well as increasing job satisfaction. When implementing these above strategies, we also had to manage some challenges such as ensuring Laboratory Animal Allergen (LAA) exposure was kept as low as reasonably practicable and maintaining the health status of animals that are immunocompromised. Here we report on the process and benefits of improving rat welfare in a research setting.

Scientific Programme77POSTER DISPLAYSCAMERON BACKCancer Research UKJESSICA CIUPACancer Research UKChronic liver disease modelsHard hitting toothAt the Cancer Research UK Cambridge Institute, technicians assisted with a chronic liver damage model used to understand how normal and malignant stem cells, (marked by fluorescent reporters), behave in response to the liver damaging agent diethoxycarbonyl 1,4-dihydrocolidine (DDC). This model, developed by the Gilbertson lab, works to directly address how the cancer cell of origin is critical in dictating various aspects of cancer risk biology, (both natural and environmental factors), as well as cancer cells’ ability to form and progress to metastatic disease, (the spread of cancer cells across the body). The findings from this type of model could prove critical in expanding the knowledge of the biology of cancer. This poster discusses the model and methods implemented to improve the welfare of the animals whilst considering what further refinements could be made for future studies. Malocclusion is a common dental disorder found in laboratory rodents. To minimise and prevent suffering caused by overgrown teeth, a regular welfare check at 5 weeks was implemented named the ‘Post Wean Check’ (PWC). A retrospective analysis was done on health concerns and found dead reports of malocclusion, to investigate whether there was a significant increase in health concerns found, and a significant decrease in found dead reports. The data showed a significant increase in health concerns and no significant difference in found dead reported after the implementation of the PWC. A limitation of this study was the lack of control of variables, due to being a retrospective analysis on the database. There is a potential of found dead reports not appropriately listed under malocclusion, with no ability to investigate further detail/information due to being a retrospective analysis. To further investigate the findings of this project, a future project could compare two facilities: (1) with a regular PWC and (2) without a regular PWC. A timed experiment with images of maloccluded dead mice, would be used to determine whether an implementation of PWCs can improve a technician’s ability to identify malocclusion.

Scientific Programme78POSTER DISPLAYSBETHANY TOUGHNewcastle UniversityIntroducing rat playpens - the effects on rats, technician time and budgetThe use of rat playpens is topical and technicians from the Comparative Biology Centre, in a bid to increase the overall welfare of the rats in research, were keen to introduce them. We have been trialling the use of repurposed Marmoset cages as self-contained ‘rat playpens’ which reduces the impact on technician time, upcycles current underutilised equipment and provides multi-dimensional stimulation opportunities.We focussed on playpens as a refinement due to the current lack of:- Research in rat enrichment and its potential positive impact on animal welfare.- Stimulating rat enrichment used in our own establishment and available commercially.Engaging with and introducing such changes can be challenging but with gradual influencing and demonstration of benefits we can witness an impact on the behaviours exhibited by the rats, without impinging on technician time or generating huge expense to budget.FLOYD LANIYANKing’s College LondonThe benefits of study plans to facility managementStudy plans were brought in at KCL, Guy’s Campus at the start of the COVID-19 pandemic to manage work that was being carried out in our facilities. It very soon became clear that study plans were an excellent tool for managing much more than just a knowledge of what was going on. We have since used study plans to manage personal and project licence compliance, 3Rs, training records, business management, occupational health status and more. This poster will present the evolution of our study plan process across our establishment including the use of different systems to empower management to run our facilities more efficiently and to a higher standard.

Scientific Programme79POSTER DISPLAYSTOM CHILDSFrancis Crick InstituteAutomation of legislative reportingThe Crick has been working on creating a suite of reports to present data to our scientists and staff in a digestible manner. Powered by Power Bi, SQL and Python, we automate processes as well as extract and manipulate data from a variety of databases for visualisation to end users. This ranges from automated emailing system to notify scientists of potential condition 18’s, reports for colony management and the more complex reporting such as calculating and presenting the home office returns for PPL holders to review before submitting. With this we hope to make legislative reporting faster and as pain free as possible while improving uniformity across the Institute.LYDIA COLGATEFrancis Crick InstituteMouse behaviour core at the Francis Crick InstituteThe Mouse Behaviour Core is a self-service area of the animal facility, located in one of our three experimental units. It provides a dedicated area to perform behavioural testing of genetically altered mice to determine the effect that gene alteration has on behaviour, memory, learning and motor function, when compared with wild type mice. The requirement of expanded Containment Level 3 facilities led to the relocation of our previous behaviour suite and provided the opportunity to create a new area specially designed for various behaviour tests. It has been running for just under a year and has allowed researchers to carry out a variety of behaviour related research under Project Licence authority. In this poster we are going to cover how the Biological Research Facility and associated Animal Technicians support the scientists to carry out their research whilst ensuring that Animal Welfare is kept to a high standard.

Scientific Programme80POSTER DISPLAYSNICOLA GOODWINAnne McLaren BuildingCambridge Biomedical CampusContainment of Mycobacterium marinum within a CL2 aquatics areaElimination of Mycobacterium marinum within Guppy ColoniesThe Zebrafish health and welfare database – where are we now?With the use of fish in research continuing to rise, the requirements to adapt facilities for housing multiple species have grown. In many instances the introduction of new aquatics species requires room alterations, building management system amendments, compliance with regulations differing to that of the mammalian species and even structural modifications. At Cambridge University, we have created a Containment Level 2 (CL2) aquatics facility, housing multiple species of fish infected with Mycobacterium marinum. Here we define the PPE used to prevent the spread of Mycobacterium marinum in a multi-roomed facility, the CL2 system design solutions, training, fish feeding and screening of fish within the facility.In 2022 the University of Cambridge and The Francis Crick Institute collaborated to import 20 species of guppies infected with Mycobacterium marinum. The aim was to eradicate the Mycobacterium marinum pathogen within 2 new generations by careful housing and breeding within the University of Cambridge Containment Level 2 (CL2) facility. Following screening and negative results for marinum, the fish are exported to the The Crick Institute for studies into the evolution of the placenta. Here we show the importation, housing, husbandry, breeding and control measures in place for the eradication of Mycobacterium marinum at the University of Cambridge before exporting to The Crick.Working in collaboration Zebrafish specialists and veterinarians created a Zebrafish welfare database combining welfare terms, severity scores and images to form a resource for the Zebrafish community. The Zebrafish welfare database provides a platform for a standardised approach, ensuring the consistency of language and severity scoring used across facilities. This provides the capability to raise awareness of potential health concerns specific to genetic background or environmental impacts on the health of the animal. By standardising the terms and severity scores used, husbandry requirements can be shared as a community to ensure the welfare of the animal, create consistency across facilities and compliance with regulations. Here we review where the database is now and how it is used within Cambridge University aquatics facilities.

Scientific Programme81POSTER DISPLAYSFILIPA PEREIRA LOPESAstraZenecaCore needle biopsy – novel requirement techniqueTo fill the gap of adopting a translational tool to sample tumours specimens in mice, we assess and validated this unique capability using core needle biopsies (CNB) sampling method for preclinical tumour models. Tumour sampling for diagnostic or research purposes has been established in the clinic but not for preclinical cancer models. CNB yields a relatively large intact tissue fragments, therefore providing suitable samples for demanding pharmacodynamics (PD) endpoints such as imaging, proteomics and genomics. In conclusion, repeated tumour sampling using CNB enables a potential reduction of number of animals required for an in vivo study while accelerating data and sample generation (e.g., running an efficacy and PK/PD in a single study.CNB may be used to characterise heterogenous tumour responses (responders and non-responders) over the course of the study. Pre-treatments biopsy may enable predictive biomarker assessment ahead of clinical trials.MEGAN HICKMANAstraZenecaAn assessment of rat hammocks as enrichmentResearch has shown there are numerous welfare and scientific benefits to housing rats in more enriched and environmentally complex housing as oppose to conventional housing. With the aim of increasing environmental complexity, providing opportunities for climbing and exploring and providing additional cover a hammock prototype was designed to implement into double decker rat cages. The hammock was trialled with a group of female rats to assess durability, impact on behaviour and preference over other shelter enrichment types namely, tunnels and corner huts. The number of observed enrichment interactions indicated a strong preference for the bottom tier of the hammock, suggesting the hammock is a successful enrichment item.

SOCIAL PROGRAMME17.00INTRODUCTION TO CONGRESSIf this is the first time you have attended Congress or have come on your own and don’t know many peopleor simply want to know where you are going ... then we welcome you to this ‘Introduction’Meet in the Beaumaris Lounge (Level C2)19.00WINE RECEPTION AND BUFFET DINNERServed in the Trade Exhibition Hall(Caernarfon Suite Level C1)until 22.30TRADE RECEPTIONThis evening is the official opening of the Exhibition and our trade partner colleagues have lots in store to show and entertain you with their products, services, games and fun …Tuesday21March82 Social Programme19.30DINNERMake your way to The Grill Restaurant situated on site at the Golf ClubAnd be entertained by MAGIC MATT “I wanted to be Houdini but all I’ve got is spongy balls …”Should be a unique and interesting evening!Wednesday22March

SOCIAL PROGRAMME20.00 – 02.00GALA DINNER DANCESmart dress required (No jeans, t-shirts, trainers or fancy dress please)Held in the Lower Ground Floor Hall at the Convention CentreThe formalities are over, the awards presented and the drinks are flowing …now it’s time to really get the party into full swing!With THE BROTHERHOODThere will also be a DISCO to complete a great night(Bar areas will be open for those who prefer a quieter end to the evening)Congress Badges must be worn by EVERYONEThursday23March83Social ProgrammeMAGIC MATTAmongst his many and varied performances during his career, Matt Redmond performed for HRH Prince Charles, now King Charles III, during a garden party held at Buckingham palace to celebrate The Prince’s Trust.He is a member of the Magic Circle and in 2016 progressed to the TV stage of Britain’s Got Talent.THE BROTHERHOODThe Brotherhood experience really is the ultimate in performance, style and production, bringing its own unique stamp to the world of live music. There’s music to suit everyone; from the disco child of the 70s, the craziest synth pop dude of the 80s, the alternative sound of the 90s and the indie rock of 2000s. Whatever your musical persuasion and taste, The Brotherhood will be sure to spin you right round- and will see you diving into party mode!

TRADE EXHIBITION84 Trade ExhibitionWednesday 21st March 16.30 Beaumaris SuiteIt’s fast, sometimes furious and definitely fun!There is Just A Minute given to each company to positively enthral you about their services and products.We have 19 companies participating this year.Time Company16.31 Fisher Scientific16.32 LASA16.33 Scionics16.34 TPS/Gruenberg16.35 LBS16.36 Datesand16.37 IPS16.38 Plexx16.39 Transnetyx16.40 Avidity Science16.41 SCANBUR16.42 UNO 16.43 Castium 16.44 MMM Medical16.45 Sychem16.46 Agenda16.47 Charles River16.48 Tecniplast16.49 a-tuneFlash Trade PresentationsAnimal Technology – supporting the Technician Commitment

LOADINGFIREFIREFIREFIREFIREENTRANCEENTRANCEENTRANCEENTRANCEENTRANCEENTRANCE6Lomir4SAFE3TPS19Marshall15Scionics14Southern29LASA13MRCAdvance11Ellegaard1AS-ET10Fisher12FERAScientific28LBS /Surrey Diagnostics23VetTech32NKP8PLEXX7IPS26Scanbur17Avidity18UNO BV27Castium9MMM Medical24Inotiv25Sychem21Charles River22Tecniplast20Agenda16Idexx2IAT31Temsega5Transnetyx/ a-tune30DatesandFIRELUNCH AND REFRESHMENTS86 Trade ExhibitionTRADE EXHIBITION HALLCongress 2023CONGRESS

Company / Institute Stand NoAdvance - MRC Harwell 13Agenda Life Sciences 20AS-ET 1a-tune software AG 5Avidity Science 17Castium Ltd 27Charles River 21Datesand Ltd 30Ellegaard Göttingen Minipigs 11Inotiv 24Fera Science 12Fisher Scientific 10IDEXX BioAnalytics 16Institute of Animal Technology 2IPS 7Laboratory Animal Science Association 29LBS (Serving Biotechnology) 28Lomir Biomedical 6Marshall BioResources 19MMM Medical Equipment UK 9NKP Isotec 32Plexx BV 8SAFE - Rettenmaier UK Ltd 4SCANBUR 26Scionics Computer Innovation GmbH 15Southern Scientific Limited 14Surrey Diagnostics Ltd 28Sychem 25Tecniplast 22Temsega 31TPS/Gruenberg Dry Heat Sterilizers 3Transnetyx 5UNO Life Science Solutions 18Vet-Tech Solutions Ltd 23Exhibitors’ Index by NameCompany / Institute Stand NoAS-ET 1Institute of Animal Technology 2TPS/Gruenberg Dry Heat Sterilizers 3SAFE - Rettenmaier UK Ltd 4a-tune software AG 5Transnetyx 5Lomir Biomedical 6IPS 7Plexx BV 8MMM Medical Equipment UK 9Fisher Scientific 10Ellegaard Göttingen Minipigs 11Fera Science 12Advance - MRC Harwell 13Southern Scientific Limited 14Scionics Computer Innovation GmbH 15IDEXX BioAnalytics 16Avidity Science 17UNO Life Science Solutions 18Marshall BioResources 19Agenda Life Sciences 20Charles River 21Tecniplast 22Vet-Tech Solutions Ltd 23Inotiv 24Sychem 25SCANBUR 26Castium Ltd 27LBS (Serving Biotechnology) 28Surrey Diagnostics Ltd 28Laboratory Animal Science Association 29Datesand Ltd 30Temsega 31NKP Isotec 32Exhibitors’ Index by Stand No.Trade Exhibition 87TRADE EXHIBITION HALL

TRADE EXHIBITIONTrade Exhibition88Trade Partners ExhibitionAdvance MRC Harwell Stand 13What is Advance?Advance is a state-of-the-art scientific training centre dedicated to training and skills transfer within the life sciences. Located at MRC Harwell, Advance offers a mixture of practical and theoretical courses in laboratory animal science and genetics to the research community worldwide.The centre is purpose built to deliver high-quality scientific training. The centre brings together some of the country’s experts in laboratory animal science to provide engaging training courses in mouse genetics, genome editing, pathology and laboratory skills. Our goal is to address the vital need to develop skills in life sciences by expanding training and education opportunities for researchers and technicians. We aim to deliver quality training courses that develop the expertise that scientists can offer in a competitive global research industry, whilst maintaining a strong emphasis on Animal Welfare.As a wide-reaching knowledge and research base, we aim to develop links with external training providers, including academic organisations, societies and commercial companies, to support, collaborate and produce bespoke training courses. Advance also offers unique facilities, including laboratory space equipped to support in vivo techniques alongside seminar rooms and modern meeting spaces for workshops and training courses.training@har.mrc.ac.uk www.har.mrc.ac.uk/training +44 (0) 1235 841438Agenda Life Sciences Stand 20Life Science RecruitmentChoosing Agenda as your resourcing partner means you receive a service which provides you with choice, not compromise. As the only life science recruitment agency that actively runs our own research facilities, working with Agenda means you take advantage of our unique position within the industry. Our team fully understand the specific requirements of the sector and develop a bespoke service for each of our clients’ needs. You will benefit from our specialist recruitment team who have worked directly in life sciences and are experts at understanding this sector’s very specific requirements.

TRADE EXHIBITIONTrade Exhibition89Temporary staffing solutionsIf you need extra resource for a specific research project, cover for sickness, maternity or holiday cover, Agenda are perfectly placed to help. Through carrying out comprehensive background checks, interviews, and inductions we ensure that you are provided with only the best candidates. Every technician holds relevant qualifications and proven experience to provide you with the perfect staffing solution.Executive Search serviceOur Executive Search service includes C-suite, Director level and Commercial searches as well as succession planning and Non-Executive Director positions. Through developing trusted partnerships with our clients, we’ll ensure you are perfectly equipped with the right talent to take your business forward.Flexible Facility Management Research projects are unique and require a tailored Facility Management service to grow with your ever-changing requirements. Outsourcing means you further your research success by centring your focus on your projects and studies. Whether you need a full-service solution at a site or want to control your research in one of our state-of-the-art facilities, Agenda provide a partnership approach to suit. Here are just some of the things we can help you with as part of our service:l compliance and regulatory oversight l animal care and welfare l staffing solutionsl procurement and budgetingFor more information visit www.agenda-fm.co.ukAgenda Veterinary ServicesAgenda Veterinary Services offers you and your team 24/7 access to our team of highly experienced Veterinarians. Their experience includes providing NVS services to Academic, Pharmaceutical, Contract Research and Government Research Institutes for over 35 years. Agenda welcomes new division through Allentown partnershipAllentown has restructured its UK operations to continue the long-term, enhanced service you expect of a quality solutions provider. They have exclusively partnered with us at Agenda to create a dedicated division, delivering the full wrap-around on sales, service, and customer support. This partnership ensures you remain delighted with Allentown’s products and approach to customer satisfaction.For more information visit www.allentown.co.uk hello@agendalifesciences.co.uk https://www.agendalifesciences.com/ +44 (0) 8456 445545

TRADE EXHIBITIONTrade Exhibition90Animals in Science - Education Trust Stand 1AS-ET is a charity registered under the UK Law with the objective of advancing education and promoting excellence in the care and welfare of animals used in science.The trust’s main activity is providing bursaries to enable technical staff who are involved in the care and welfare of laboratory animals to attend training courses and to undertake educational study. To date the trustees have awarded around £180,000 in bursaries, many of which enabled applicants to obtain co-funding from their employers. In addition to providing bursaries AS-ET has awarded grants to support the development of new courses and educational meetings. We provide three annual educational prizes for each level of the IAT higher education qualifications, a LASA 3Rs prize and a prize for the best Tech-2-Tech article in Animal Technology and Welfare – IAT Journal.In order to be able to fund these activities we rely on generous donations. The trustees are extremely grateful to our corporate sponsors who give great support to AS-ET, as do our ambassadors including the IAT and the IAT West Middlesex Branch. We also organise fund-raising activities and benefit from IAT Branches who hold events for us. We have a good number of individual supporters who share our objectives, but we are always in need of more. Donations can be made by standing order if an individual wishes to donate a minimum of £25 a year to AS-ET.Please do visit our stand to find out more about AS-ET, how you or a colleague might benefit from a bursary and how you can help support our work. Visit our website for more information and access to the bursary application process.contact@as-et.org.uk www.as-et.org.uka-tune Software Stand 5tick@lab animal research facility software helps you effectively manage your animal care, operations, and compliance processes. Get the power of one secure access point to the information and functionality needs for all stakeholders – from researchers and facility staff to compliance personnel and management.tick@lab includes:l management of Project and Personal Licenses

TRADE EXHIBITIONTrade Exhibition91l management of training and competency records l animal orderingl colony and breeding management l aquatic management l animal facility managementl animal and animal health management l task managementl Home Office documentation and reportingl AWERB review and document managementl cost accountingl bill and cost recovery tick@lab offers:– Built-in Flexibility - administrators have the power to configure templates, forms, cage cards, reports and even the user interface including labels, grid views and field properties.– Integration Capabilities - tick@lab has been built for integration with existing applications, we offer a variety of web services and API’s and diverse integration technologies.– Browser independent web application – ready for mobile use, no client installation required, support for all standard browsers on all types of client devices including tablets.– Audit Trail - Full audit trail capability to fulfil CFR21 Part 11 requirements and to enable GLP validation.– tick@lab from the Cloud - tick@lab is available as a secure, fully managed cloud service reducing infrastructure requirements to the browser and the internet connection.In synergy with our clients business objectives we:l optimise work and data flows l create transparency for users (supporting the 3Rs)l guarantee governance, compliance and best practice l lower expenses and risksResearch-Driven Organisations rely on a-tune50,000+ Users Worldwide5 / 7 Top Pharmaceuticals140+ Research Institutions100+ World-Renowned Universities20+ Countriessales@a-tune.com https://www.a-tune.com/ +49 6151 95131-29

TRADE EXHIBITIONTrade Exhibition92Avidity Science Stand 17Avidity Science serves the scientific research and biomedical industries on a global scale. We pride ourselves on enabling science to improve the quality of life. Edstrom watering systems deliver clean, controlled water to all of your laboratory animals. Regardless of the size of your research facility, Edstrom has the products, technology and support to make it secure and efficient.Animal WateringAutomated watering solutions for every laboratory animal species, meeting the needs of all types of facilities to provide their animals with continuous access to clean, fresh, water.Monitoring and ControlWe offer specialised products for monitoring and controlling a number of environmental factors, such as light, humidity, temperature and differential pressure.Water PurificationOur line of water treatment and purification systems are specifically tailored to provide exceptional water quality, regardless of the condition of your incoming water.EMEA.info@avidityscience.com www.avidityscience.com +44 (0) 1844 201142Castium Stand 27Facilities within Research and Academia play a vital role in carefully understanding, exploring and finding improvements and solutions to specific problems and concerns by using scientific methods. The abundance of micro-organisms, animal and plant species within facilities offers decontamination companies a never-ending variety of projects to undertake allowing the integrity of the work being carried out to continueCastium work with a multitude of Research and Academic Facilities and are at the forefront of designing programmes to eradicate a variety of contaminants in challenging areas. Castium have endeavoured to provide a comprehensive array of quality decontamination solutions under a single provider. Through a wealth of experience Castium’s Senior Consultant team can provide clients with assurance that the proposed decontamination process is best suited to individual requirements.Castium support Laboratory Animal Science by developing bespoke decontamination solutions.

TRADE EXHIBITIONTrade Exhibition93Castium offer:l turnkey solutionsl commissioning and decommissioning programmesl equipment storagel deep cleaningl pinworm decontaminationl equipment sterilisationl facility fumigationl validationl LabTACK- regenerating contamination control flooringenquiries@castium.co.uk www.castium.co.uk +44 (0) 345 900 3767Datesand Ltd Stand 30Since the birth of Datesand in 1980, we have empowered our industry to improve lives by developing and supplying innovative products and services to the biomedical science sector. Our work enables the advancement of biological science.As a family-run business, we have built our reputation through hard work and dedication to our industry since 1980. Datesand strives to provide our valued customers with the most reliable and friendly service.By meeting and exceeding the everyday supply needs of our customers for over 40 years, we have unrivalled experience in the Biotechnology sector.sales@datesand.com https://datesand.com/ +44 (0) 161 274 1080Fisher Scientific Stand 10The Fisher Scientific Channel is Your Scientific and Safety MarketplaceThe Fisher Scientific channel is ‘the’ premier scientific marketplace and has defined unparalleled choice and convenience for over a century. Focussed on delivering innovative

TRADE EXHIBITIONTrade Exhibition94yet eminently practical solutions, we have developed a comprehensive portfolio of safety products, chemicals, laboratory equipment, supplies and servicesOur portfolio is aimed at helping customers increase productivity and drive innovation in a variety of sectors, including the pharmaceutical and biotech industries, clinical diagnostic and research laboratories, hospitals, universities, and government agencies, as well as in environmental analysis and industrial process control — all with greater ease and efficiency than ever before.The Fisher Scientific channel’s extensive portfolio of over 2 million products, from over 2,000 suppliers, provides you with choice - enabling you to conduct your research or execute on your research strategy ensuring that you do so with laboratory safety in mind. We supply safety products from all the major global brands with a dedicated European safety team to support your safety needs. Whether you are looking for support for your safety requirements for your cleanroom production processes, or for safety products for your laboratory, you can rest assured we have the products you need.Darren.blincow@thermofisher.com www.fishersci.co.uk +44 (0) 7825122394IDEXX BioAnalytics Stand 16Dedicated to providing advanced solutions and support to push research forwardQuality that exceeds expectations, innovation that expands possibilities, and world-class expertise that instills confidence, all in one powerful partnership: IDEXX BioAnalytics and you.IDEXX BioAnalytics customers can rely on a dedicated point of contact who understands their unique needs. With access to a network of experienced industry experts, we are always ready to draw on our experience to answer any questions.Animal Health Monitoring - Expect the power and innovation of a leader with something more: the responsiveness and support of a trusted partner.Preclinical Services - Prompt, accurate results to support early discovery, R&D, and global development programmes.Biologics - Independent confirmation for the quality, safety, and authenticity of biological materials.idexxbioanalytics-europe@idexx.com https://www.idexxbioanalytics.eu +44 (0) 7342 714 100

TRADE EXHIBITIONTrade Exhibition95Inotiv Stand 24Inotiv Inc., is a leading contract research organisation specialising in nonclinical and analytical drug discovery and development services. The Company focusses on developing innovative services supporting its clients’ discovery and development objectives for improved decision-making and accelerated goal attainment. The Company’s products focus on increasing efficiency, improving data, and reducing the cost of taking new drugs to market. Visit inotivco.com for more information about the Company.walter.swan@inotivco.com https://www.inotivco.com/ +44 (0) 7778 165923Datesand Ltd IFC IPS Product Supplies Ltd 20Institute of Animal Technology 30/ IBCLBS Serving Biotechnology Ltd OBCMarshall BioResouces 3Tecniplast UK 16-17Sychem 4Vet-Tech Solutions Ltd 24INDEX TO ADVERTISERS PageAnimal Technology – supporting the Technician Commitment

TRADE EXHIBITIONTrade Exhibition96Institute of Animal Technology (IAT) Stand 2The Institute of Animal Technology (IAT) was founded in 1950 and its purpose is to advance knowledge and promote excellence in the care and welfare of animals in scienceThe IAT recognises and supports the benefits arising from research involving animals and its members are committed to the principle that excellence in animal care and welfare is essential for excellence in science.Representing Animal Technologists both within the United Kingdom, and around the world, the IAT has over 2500 members, which includes the vast majority of the UK’s Named Animal Care and Welfare Officers (NACWOs) for which the Institute awards the accredited training on behalf of the Home Office.Education, qualification and continuous professional development for Animal Technologists is the primary role of IAT Education www.iateducation.co.uk. The website has all the resources that members need when considering furthering their education, whether they’re considering a diploma or apprenticeship. IAT Education continues to be recognised by Ofqual as an Awarding Organisation, awarding diploma qualifications, FE and HE Levels 2 through to 6 qualifications in laboratory animal science and technology. IAT Education are End Point Assessors (EPA) for Level 2 and 3 apprentices. IAT members are now able to access and apply for these courses through the IAT Membership database https://my.iat.org.uk/The IAT’s award winning Career Pathway www.iat.org.uk/pathway for Animal Technologists is now widely recognised throughout the UK and has been adopted as a template by other countries.admin@iat.org.uk www.iat.org.uk www.iateducation.co.uk

TRADE EXHIBITIONTrade Exhibition97IPS International Product Supplies Ltd Stand 7Consider Our Warehouse as Your Warehouse!With vast experience of laboratory animal facility management, IPS has a genuine understanding of the daily challenges that running an animal unit can bring. We know that the supply of critical consumables and associated services must run like clockwork and be something you need not worry about. For this reason, IPS’ chosen industry partners have to provide us with products of the very highest quality standards whilst adhering to our strict supply-chain schedules.Whether it is Laboratory Animal Diets, Bedding or Enrichment, our warehouses are filled with the products you need on a constant basis so that we can deliver them at a time to suit you and staff levels. Conveniently based in Central England, we offer a fast and efficient service to our growing number of customers. For more information, please visit our stand and say hello to the IPS Team.enquiries@ipsltd.biz http://www.ipsltd.biz/ +44 (0) 870 600 1616

TRADE EXHIBITIONTrade Exhibition98Laboratory Animal Science Association (LASA) Stand 29The UK society for scientists and laboratory animal professionals with an interest in animal research, 3Rs, care and welfare, education and training, ethics and policy and regulation of animal research.LASA was founded in 1963 by a consortium of industrial, university, ministry and research council representatives – a breadth of interest which is still typical of the LASA membership today. Through our mission statement ‘To advance scientific understanding and knowledge of the use, care and welfare of laboratory animals and promote refinement, reduction and replacement’ we aim to encourage and facilitate education and training in laboratory animal science.LASA promotes the interchange of information through meetings, lectures, discussions and publications. There are seven specialist sections of LASA which together provide a forum to discuss the latest developments in the areas of specialised scientific interest.We welcome applications of membership from Individuals and Organisations.In 2023, LASA celebrates its 60th Anniversary. There will be many CPD events throughout the year including a special 60th Anniversary Conference! info@lasa.co.uk https://www.lasa.co.uk/ +44 (0) 8456 711956

TRADE EXHIBITIONTrade Exhibition99LBS (Serving Biotechnology) Stand 28As an independent family run business since 1939, where integrity still counts, heritage and tenacity runs through the very veins and DNA of LBS. These have played no small part in its success as a leading supplier of diet, bedding, consumables and services to the biotech industry as we head into our 82nd year. Whilst the company takes immense pride in its heritage we recognise that it is only through a relentless and a consistent focus on meeting and exceeding the requirements of our domestic and international customers in the biotechnology industry that we maintain this position.We offer a combination of tried and tested products and through a continual process of product development, new innovative product solutions. All of this is backed through our commitment to ISO 9001:2015 quality assurance, customer service and logistics management. This is further underpinned and developed through a process of working closer with the understanding our customers’ needs, at which we aim to excel.Contact us for expert advice on:l research and zoo dietsl research bedding and nesting materiall environmental enrichment productsl PPE including clothing and footwearl AniBio animal facility management software – covers all your essential needsl disinfectants and all allied productsl bespoke irradiated packaging and suppliesl specialist vacuum / floor care productsl broad range of specialist equipment and products for Animal Technologistsl price promisel LBS owned and run logistics sales@lbs-biotech.com http://www.lbs-biotech.com/ +44 (0) 1293 827940

TRADE EXHIBITIONTrade Exhibition100Lomir Biomedical Stand 6An industry leader since 1989Lomir is the world’s largest manufacturer and designer of animal jackets, infusion products, restrainers, handling equipment, and enrichment products. Our team has built on decades of experience to provide consistent quality, predictable turnaround times, and expert consultations, to better understand your needs. In fact, these discussions have often led to improvements in research quality and streamlined processes on the client side, as well as the development of customised products. Commitment to integrityLomir’s success is founded on respect for integrity and its absolute commitment to customer satisfaction. Biomedical research is a costly venture and Lomir’s durable and reliable products reduce or eliminate many of the factors that compromise investigations whether they involve toxicology, pharmacology, physiology, neuroscience, or veterinary science. The ethical treatment and well-being of research animals are of paramount importance and Lomir’s testing, and restraint equipment is designed to minimize discomfort and stress levels, thereby protecting the integrity of the procedure.Innovative design is a Lomir hallmarkWe continually incorporate modern materials and techniques. Today’s jackets, undershirts, and restrainers are available for increasingly diverse applications, from video tracking in group housing, to dermal applications, ambulatory infusion, and remote data collection through smart fabric—all while ensuring animal comfort. Most recently, Lomir launched new rodent harnesses, rabbit pants, and an extensive range of options and customisations for large animal jackets. The futureAs technology evolves, we expect to see: developments in integrated electrodes and smart textiles; printable, flexible circuits applied to the skin like a Band-Aid; moisture-wicking fabrics; ultralight devices.A valued partner If you have a question or unique research problem that you would like to discuss, please contact us and we will suggest and design an appropriate product for your specific needs. The impossible is only an unexplored idea.daniel.westley@agendalifesciences.co.uk https://www.lomir.com 03456 44 55 45

TRADE EXHIBITIONTrade Exhibition101Marshall BioResources Stand 19Marshall UK is a division of Marshall BioResources Inc., and our Home Office designated breeding and supplying facilities are located in East Yorkshire near Hull and at Wyton in Cambridgeshire. We supply Marshall Beagles® and have full barrier facilities for the production of ‘Influenza-free’ Marshall Ferrets® and SPF Guinea pigs and mice. Using flexible film isolators, we breed the IFNAR type 1 and type 2 interferon receptor KO mice (A129 and AG129) as well as the wild type control (129 SvEv). Our SPF Dunkin Hartley Guinea pigs have a high health status (being free of CMV and PI3).Our Scientific Services team offers a highly regarded animal Health Monitoring Service and we are able to carry out health screening at your site or, using our collection service, your sentinels can be brought to Grimston for testing.Biological matrices from a range of donors (rodents, Marshall Beagles®, rabbits, humans, NHPs and farm animals) are also available. We offer a very quick turnaround of your orders for whole blood, plasma, serum, tissues and many other bioproducts.Visit our stand to pick up a set of current literature or contact us after the event.BNKsales@marshallbio.com https://www.marshallbio.com/ +44 (0) 1964 527555MMM Medical Equipment Ltd Stand 9Complete Solutions for Infection ControlThe MMM Group MMM have supplied Sterilising Equipment to both Laboratories and Research Institutes for over 69 years and are one of the strongest Manufacturing Groups in Europe. MMM Sterilisers are designed with reliability built in offering you peace of mind for your facility. Each stage of manufacture, installation and after sales care is quality controlled to provide the long-life cycle you need. This level of reliability and continued after sales and service support has earned us Preferred Supplier Status with many of our clients. MMM UK, a wholly owned subsidiary of the MMM Group, is centrally located in Leeds since 1997. Since that time, we have worked hard to earn and maintain our excellent reputation for Autoclave quality and reliability in both the UK and Ireland.

TRADE EXHIBITIONTrade Exhibition102All MMM equipment complies with all relevant European standards and directives.Steriliser chamber sizes from 150 to 9000+ litres – our comprehensive range is sized to allow easy access for single and double sided IVCs.Single sided or double door pass-through options available.sales@mmm-group.co.uk https://www.mmmgroup.com +44 (0) 113 3910717Plexx BV Stand 8With nearly 30 years of experience in the pharmaceutical and biomedical industry, we have a proven track record of providing high quality products and outstanding customer service. Animal Identification Injectable transponders with unique identification codes and temperature measurement.Individually ventilated Micro Isolator systems Protect both your staff and animals with our positive cage in a negative rack design. Zebrafish and Xenopus Housing SystemsNewly designed tanks and racks with remote access and control.Hydropac An innovative way to deliver water to rodents using pouches and single use valves.Anaesthesia equipmentUser friendly equipment.Automated Home Cage Euthanasia SystemsHumane gradient CO2 systems for small, medium and large numbers of cages. Enrichment, Treats and Special DietsFor all laboratory animal species.uk@plexx.eu https://www.plexx.eu/ +31 481 377797

TRADE EXHIBITIONTrade Exhibition103SAFE® Stand 4Your System Partner for Laboratory Animal ScienceWe offer complete solutions for your research work. We supply diets, custom diets, bedding and environmental enrichment, in a range of packaging formats, delivered to you from our production facilities in France (Diets) and Germany (Bedding and Enrichment). We have a UK warehouse to support our supply chain, and our reliability of supply to you, and we also work with our Distributor partners to offer you a nationwide service.All our products and processes are independently certified for provenance, traceability, quality and environmental sustainability.We have a wide range of options for you, under the Lignocel, SAFE and SDS brands.Our products are available irradiated to 10kGy, 25kGy or 40kGy if required.Brian.Young@rettenmaier.eu www.safe-lab.com

TRADE EXHIBITIONTrade Exhibition104Scanbur Stand 26SCANBUR has 50+ years of experience within the Life Sciences industry and we actively develop, manufacture, supply and service innovative high quality animal facility laboratory products. We excel in cleanroom products vital to the highest welfare standards demanded by Home Office Compliance.We work in continuous close collaboration within the Industry and refine our product design and development with the aim of improvements in Animal Welfare, Allergen Control, Ergonomics, Health and Safety and Sustainability.All SCANBUR representatives have extensive Life Sciences industry experience.Our customers are our primary resource and sounding board, customer care has top priority.We always welcome our customers to visit our head office, showroom and manufacturing site which is situated near Copenhagen in Denmark.We look forward to welcoming you at our trade stand during IAT Congress 2023!jow@scanbur.com www.scanbur.com +44 (0) 7923 320 519pjo@scanbur.com +44 (0) 7572 706 022 Scionics Computer Innovation GmbH Stand 15Scionics Computer Innovation is an IT service and software provider specialising in solutions for the biological science research community. With more than 20 years of experience working in scientific research environments, our highly qualified professionals have diverse skills and extensive experience in scientific research, IT consulting, and outsourced settings. By utilising state-of-the-art technologies, we provide our customers the best technical solutions possible for their research needs. The Scionics Product division is ISO 9001 certified.Our PyRAT line of animal facility software products is the solution to your animal facility management needs. Designed and continuously refined in close collaboration with our users, our PyRAT products save you time and money. All data is safely stored in a central, backed-up, database and can be easily and securily accessed using any device with a web

TRADE EXHIBITIONTrade Exhibition105browser. All stakeholders, including researchers, facility managers, facility staff, etc. have controlled access to data and features, with the ability to customise and store their view to their data.Our products are made to decrease your risks, structure and document your work, as well as decrease your workload.Discover our PyRAT products:l PyRAT Animal Facility Softwarel PyRAT Transgenic Editionl PyRAT Aquaticproducts@scionics.com http://www.pyrat.com +49 351 202 707 08Southern Scientific Ltd Stand 14Southern Scientific is part of the LabLogic Group of companies.As an organisation we specialise in the supply of products and solutions concerning the detection and measurement of radiation. We do this across an array of market sectors. One of our focus areas is within life sciences, whereby we offer imaging solutions for pre-clinical imaging. Distributing for the likes of MOLECUBES and Spectral Instruments Imaging, we support our customers in imaging modalities such as PET, SPECT, CT and Optical Fluorescence and Luminescence.info@southernscientific.co.uk https:www.southernscientific.co.uk 01273 497600

TRADE EXHIBITIONTrade Exhibition106Surrey Diagnostics Ltd Stand 28We specialise in providing independent screening services in laboratory animal health monitoring. Our staff have a wealth of experience in microbiology, serology, molecular biology and veterinary pathology. Through this expertise, SDL can provide consultancy services in all aspects of laboratory animal science.Here at Surrey Diagnostics, we understand the importance of developing and maintaining a comprehensive health monitoring programme as a fundamental part of successful research. It’s our aim to give clients the most scientifically accurate health monitoring service on the market, at a fair price, with customer service which is second to none. We use the latest appropriate and proven technologies. We advocate a highly flexible multi-disciplinary approach to health monitoring, using both conventional necropsy and non-destructive sampling techniques in combination, which we call ‘Combined Screening’. This allows a significant reduction the numbers of animals used whilst maintaining a reliable, robust health screening programme. As a complementary service to health monitoring we offer full environmental testing, including surfaces, air, water, consumables and Laboratory Animal Allergen (LAA) monitoring. We also provide possible solutions to any problems arising. We also have room sanitising systems available.If you would like any further information on the services and products we can supply, please do get in touch and we will be very happy to help in any way we can.andy@sdlab.co.uk / alistair@sdlab.co.uk (Health Monitoring) www.sdl.uk.net mark@sdlab.co.uk (Environmental)

TRADE EXHIBITIONTrade Exhibition107Sychem Stand 25Providing industry-leading animal care solutions since 1982Offering a complete portfolio of animal care solutions, services, and consumables, Sychem is an industry-leading, expert provider to research facilities across the globe.Sychem and SteelcoSychem is the UK exclusive partner for the Italian manufacturing giant Steelco S.p.A. Together, we offer a complete portfolio of autoclaves, washers and decontamination equipment; including small and medium to bulk capacity autoclaves, small to large washers, automated tunnel washers and feeding bottle treatments.Our Airflow RangeOur Airflow Range utilises Sychem’s Active Airflow Technology to protect animals and technicians. Comprised of a bedding dispenser, an animal transfer station, a waste disposal unit and a biosafety cabinet, the range maximises animal welfare, protecting users and advancing biomedical research.Discover our newest addition to the range on our stand!Tailored Servicing PackagesWith 25+ Service & Test People across the UK, we offer an extensive range of servicing options to ensure your machines continue operating to their maximum efficiency. In addition, Sychem provides a range of fully customisable services packages, tailored to meet the requirements of your facility.hello@sychem.co.uk https://www.sychem.co.uk/ +44 (0) 845 644 6824

TRADE EXHIBITIONTrade Exhibition108Tecniplast UK Stand 22Since our inception in 1949, Tecniplast has been building its global reputation for creating the best designed, best built, highest quality animal housing and washing solutions. At Tecniplast, our primary objective is simple: to keep your animals safely cared for, reliably and economically.Tecniplast have been at the heart of creating innovative solutions for over 70 years. We have an acute awareness of the continuous evolution of biomedical facilities and are proud to have the capability to design and develop products in-house - we can offer a wide range of integrated solutions to our clients.A glimpse of our Product Range:– The Alpha: the next generation cage and rack washer, redefining operational efficiency and sustainability.– A world leading range of IVC systems, including the latest jewel in our crown -Emerald Line, with housing for both mice and rats available.– Digitally Ventilated Caging (DVC): the latest home cage data capture technology.– Biocontainment and bio-exclusion caging.– Laminar Flow technology including: cage change stations, bio-safety cabinets, downflow booths, bedding disposal systems and air showers.– Washing, decontamination and logistics equipment ranging from bottle washers and fillers, rack washers, cabinet washers and decon locks.– Automation: from partial to fully automated robotic systems to assist with ergonomics, standardisation of process and throughput.Project ManagementTecniplast UK have built a reputation of high quality and consistent project management, this is due to our dedicated Project Management Team who have many years of experience in the lab animal field.We can offer you a wide range of services:– Lay outing, 3D modelling and rendering (AutoCAD and Revit).– Throughput, workflow, and workload analysis.– Return on investment consultancy.– GANTT charts integration and project time management.– On-site surveys and coordination meetings.– Validation processes (IQ, OQ, PQ, Microbiological services, FAT, SAT).– Multiple level training* (operators, managers, maintenance).

TRADE EXHIBITIONTrade Exhibition109Technical ServicesHere for you whenever, wherever you need us…We’re here to help with all after-sales and Tecniplast product support needs including:– A flexible range of preventative Maintenance Contracts– Silver Level– Gold Level– Platinum Level– Emergency Breakdown Support.– Certified Spare Parts & Consumables Supply, DOP Testing.– Installation, Commissioning, Validation, Manuals & Documentation.– Training and Support Packages.– Relocation and Re-commissioning Packages, Refurbishment and Re-conditioning Packages, Extended Warranty Packages.We can provide you with the ultimate service solution for your facility.SustainabilityWe don’t Only Re-Cycle, We Re-Cage! - Partner with us to build a better world!We are now the first Company to implement Circular Economy in the Lab Animal Science industry with our Re-Cage Programme!We’ll collect and recycle your end-of-life Polysulfone cages, cutting CO2 emissions and giving life to new, greener housing solutions.1. We collect your old/dismissed cages.2. Cages are then consolidated at our logistics hubs.3. The collected cages are processed to get the recycled PSU.4. ‘Second life’ cages are manufactured and sold to the market.No more waste management responsibilities to worry about, no more disposal costs at your expense: simply partner with us to build a better world together.info@tecniplastuk.com www.tecniplastuk.com +44 (0) 345 050 4556

TRADE EXHIBITIONTrade Exhibition110ABPIAndrew Blake Tribute AwardCC TechNotebooksDBM Scotland Delegate BagsInotiv Delegate MugsIPS Badges/LanyardsKevin Dolan Memorial LectureLBS Best Poster Prizes S3 Science Delegate PensSPONSORSHIPThe Congress Committee wish to thank all the companies that have supported Congress by Exhibiting and/or Advertising in this Handbook.The following companies and organisations are especially thanked for their further sponsorship:

TRADE EXHIBITIONTrade Exhibition111Transnetyx Stand 5Take the most efficient path to discovery and reproducibility with TransnetyxWe are passionate about empowering advancements in human health. The Transnetyx suite of services enables researchers and institutions to outsource critical tasks and functions – accelerating their paths to discovery.Individually and in combination, Transnetyx services save time, increase lab efficiencies, ensure accuracy and compliance, and enhance research reproducibility. Our solutions include the following:– Automated Genotyping - Eliminates human error and accelerates research through our fast, accurate approach.– Microbiome Analysis - Helps keep phenotypes on track by monitoring the shift in the gut microbiome.– Genetic Monitoring - Helps you reach fully congenic strains and support the reproducibility of your results.– Transnetyx Tissue - Fresh tissue and media to ensure more viable cells, putting you on the fast track to discovery.– Colony + AMI - Helps create greater efficiencies by accessing, updating and sharing your data in real-time.– tick@lab by a-tune, a Transnetyx company - Simplify the complexity of research compliance & animal research facility management by connecting teams, processes and information in a single secure platform.help@transnetyx.com https://www.transnetyx.com/ +1 888 321 2113

TRADE EXHIBITIONTrade Exhibition112Vet-Tech Solutions Ltd Stand 23A Company that prides itself on going that extra mile for all of its Customers.We have grown in size but still keep our personal approach.We are a dedicated, experienced team here to help you please just ask.We offer a wide range of anaesthetic equipment from basic models to more advanced systems all manufactured in house by our Innovative team of engineers.Specialists in producing Home Cage Euthanasing Systems all being AVMA compliant single cage or multiple cages.Various designs to fit your requirements.Other Euthanasing Systems manufactured.For all the items we produce we offer money saving Service Contracts to suit your needs and Budgets.We are specialists in working with materials such as stainless steel which can been seen in our various selection of trolleys and ergonomic height adjustable tables.Perspex as seen in our various chambers. Trespa used for Tables and Storage Systems.Polycarbonates and acrylics.Also available:l Down Draught Tablesl Dycem decontamination flooring Systeml PPEl Aldasorbersl Surgery accessoriesl Curvet Rat Training Aid l Mimicky MouseWe look forward to welcoming you to our Stand at Celtic Manor!info@vet-tech.co.uk https://www.vet-tech.co.uk/ +44 (0) 1260 274333

Enquiries to Congress Committee via congress@iat.org.uk Come and join us atCongress 202411th - 14th MarchNORTH UK VENUEDelivering a Full Scientific Programme addressing current themes Attend the wide range of Scientific Papers and Poster DisplaysVisit one of the largest Trade Exhibitions in the UKThe event will take place in a tried and tested conference venueDetails for Congress 2024 will be available on the IAT website www.iat.org.uk and published in the monthly BulletinBookings will open September 2023The largest UK event run entirely for Animal Technologists and TechniciansCongress 2024CONGRESSCongress 2023CONGRESS21st March – 24th March

Congress 2023 www.iat.org.uk 21st March – 24th MarchAnimal Technology – supporting the Technician CommitmentCongress 2023CONGRESS21st March – 24th March