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ICE PACK FOR INSIDE THE MOUTH FOR Chemo Mouthpiece FEATURES BENEFITS Cools the entire oral cavity Stays ice cold for 30 minutes No Rx required a drug free solution Developed for Cancer Patients by a Cancer Survivor ORAL MUCOSITIS FSA HSA eligible Single patient multi use Easily cleaned with soap and hot water One size fits most adults Comes with a convenient insulated cooler and carrying bag for travel Can be used by patients with sensitive teeth Excellent alternative to ice chips Made of FDA medical grade silicone water and salt AVAILABLE ONLINE ORDER TODAY Helping Patients Manage Oral Mucositis HOW TO ORDER Visit chemomouthpiece com and enter the code below for off and free shipping CMP5 CHEMO MOUTHPIECE LLC 10 Railroad Avenue Closter NJ 07624 USA 1 201 716 0693 inquiries chemomouthpiece com chemomouthpiece com

What is CHEMO MOUTHPIECE To put it simply Chemo Mouthpiece is an ice pack for inside the mouth The device is made of three components water salt and FDA medical grade silicone Its innovative design has two chambers an inner chamber filled with pure water and an outer chamber filled with salt water When the Chemo Mouthpiece is put in a standard freezer the inner pure water chamber will freeze solid but the outer salt water chamber will not The outer salt water chamber stays ice cold which allows the mouthpiece to cool a patient s oral cavity The left image below shows heat distribution before Chemo Mouthpiece was administered and the right shows after The lighter colored areas indicate the highest temperatures and the dark show the lowest As shown in these thermographic images the entire oral cavity is cooled completely with Chemo Mouthpiece Before After Images certified by thermographer Julie Conner CCT 2017 Data on File What is ORAL MUCOSITIS Chemotherapy and radiation can cause oral mucositis and ice chips are commonly used as a preventative method Chemo Mouthpiece is a more efficient option than ice as it cools the whole oral cavity not just the bottom half Oral cryotherapy used during treatment reduces blood flow by narrowing the blood vessels called vasoconstriction which limits the amount of drugs delivered to the oral cavity tissues Stopping the toxic drugs from reaching the gums and mouth may help with oral mucositis There are large bodies of data supporting the use of oral cryotherapy with many citing a notable reduction in the severity of oral mucositis Some of the most respected organizations have made recommendations based on this data A few of these very well known groups endorsing the use of oral cryotherapy when treated with mucotoxic agents are Oncology Nursing Society ONS National Comprehensive Cancer Network NCCN and Multinational Association of Supportive Care in Cancer MASCC Intraoral scanning has shown Chemo Mouthpiece will cool the gums tongue and palate entire oral cavity uniformly which is best for prevention This brochure is for informational purposes only and is subject to change at any time ORAL HYGIENE It is especially important to take proper oral care before and during treatment For best results practice good oral hygiene In addition to using the Chemo Mouthpiece during your cancer treatments or as often as needed during the day for pain relief following a protocol for good oral hygiene is recommended Your nurse oncologist or oral care team can give you strategies to follow but below are some points to remember and practice daily Outer clear chamber filled with salt water Inner blue chamber filled with fresh water Practice good Oral mucositis refers to redness swelling and sores inside the mouth It is a significant health issue for cancer patients undergoing chemotherapy or radiation and is cited as the most troubling side effect by more than 40 of patients The incidence and severity of oral mucositis varies depending on the treatment regimen and modality hh Visit your dentist prior to commencing cancer therapy hh Rinse your mouth frequently with warm salt water or a baking soda rinse hh Inspect your mouth daily for red spots or sores hh Use a soft bristle toothbrush hh Do not use dental floss if your gums are tender hh Avoid using mouthwashes that contain alcohol hh Do not use tobacco products or drink alcohol hh Avoid spicy foods and foods that are hard to chew hh Drink at least eight glasses of water daily The sores or ulcers caused by oral mucositis can become infected by bacteria viruses or fungi The resulting pain can make it difficult for patients to eat which could lead to weight loss or overall disparagement of health The pain has often been described as a burning sensation much like a sunburn on the inside of the mouth Symptoms are characterized by redness swelling dry mouth and open sores or ulcerations These symptoms can make it extremely difficult for patients to eat drink swallow speak or even sleep normally Patients suffering from oral mucositis may also require high doses of analgesics longer hospitalization and intravenous feeding to receive nutrition and maintain proper hydration Patients who develop oral mucositis are several times more likely to have unplanned breaks in their treatment and are also more likely to be hospitalized due to complications If symptoms become severe cancer treatment may have to be delayed dose reduced or even terminated which potentially reduces the likelihood of recovery Pictured is a patient suffering from oral mucositis with visible mouth sores and swelling

What is CHEMO MOUTHPIECE To put it simply Chemo Mouthpiece is an ice pack for inside the mouth The device is made of three components water salt and FDA medical grade silicone Its innovative design has two chambers an inner chamber filled with pure water and an outer chamber filled with salt water When the Chemo Mouthpiece is put in a standard freezer the inner pure water chamber will freeze solid but the outer salt water chamber will not The outer salt water chamber stays ice cold which allows the mouthpiece to cool a patient s oral cavity The left image below shows heat distribution before Chemo Mouthpiece was administered and the right shows after The lighter colored areas indicate the highest temperatures and the dark show the lowest As shown in these thermographic images the entire oral cavity is cooled completely with Chemo Mouthpiece Before After Images certified by thermographer Julie Conner CCT 2017 Data on File What is ORAL MUCOSITIS Chemotherapy and radiation can cause oral mucositis and ice chips are commonly used as a preventative method Chemo Mouthpiece is a more efficient option than ice as it cools the whole oral cavity not just the bottom half Oral cryotherapy used during treatment reduces blood flow by narrowing the blood vessels called vasoconstriction which limits the amount of drugs delivered to the oral cavity tissues Stopping the toxic drugs from reaching the gums and mouth may help with oral mucositis There are large bodies of data supporting the use of oral cryotherapy with many citing a notable reduction in the severity of oral mucositis Some of the most respected organizations have made recommendations based on this data A few of these very well known groups endorsing the use of oral cryotherapy when treated with mucotoxic agents are Oncology Nursing Society ONS National Comprehensive Cancer Network NCCN and Multinational Association of Supportive Care in Cancer MASCC Intraoral scanning has shown Chemo Mouthpiece will cool the gums tongue and palate entire oral cavity uniformly which is best for prevention This brochure is for informational purposes only and is subject to change at any time ORAL HYGIENE It is especially important to take proper oral care before and during treatment For best results practice good oral hygiene In addition to using the Chemo Mouthpiece during your cancer treatments or as often as needed during the day for pain relief following a protocol for good oral hygiene is recommended Your nurse oncologist or oral care team can give you strategies to follow but below are some points to remember and practice daily Outer clear chamber filled with salt water Inner blue chamber filled with fresh water Practice good Oral mucositis refers to redness swelling and sores inside the mouth It is a significant health issue for cancer patients undergoing chemotherapy or radiation and is cited as the most troubling side effect by more than 40 of patients The incidence and severity of oral mucositis varies depending on the treatment regimen and modality hh Visit your dentist prior to commencing cancer therapy hh Rinse your mouth frequently with warm salt water or a baking soda rinse hh Inspect your mouth daily for red spots or sores hh Use a soft bristle toothbrush hh Do not use dental floss if your gums are tender hh Avoid using mouthwashes that contain alcohol hh Do not use tobacco products or drink alcohol hh Avoid spicy foods and foods that are hard to chew hh Drink at least eight glasses of water daily The sores or ulcers caused by oral mucositis can become infected by bacteria viruses or fungi The resulting pain can make it difficult for patients to eat which could lead to weight loss or overall disparagement of health The pain has often been described as a burning sensation much like a sunburn on the inside of the mouth Symptoms are characterized by redness swelling dry mouth and open sores or ulcerations These symptoms can make it extremely difficult for patients to eat drink swallow speak or even sleep normally Patients suffering from oral mucositis may also require high doses of analgesics longer hospitalization and intravenous feeding to receive nutrition and maintain proper hydration Patients who develop oral mucositis are several times more likely to have unplanned breaks in their treatment and are also more likely to be hospitalized due to complications If symptoms become severe cancer treatment may have to be delayed dose reduced or even terminated which potentially reduces the likelihood of recovery Pictured is a patient suffering from oral mucositis with visible mouth sores and swelling

What is CHEMO MOUTHPIECE To put it simply Chemo Mouthpiece is an ice pack for inside the mouth The device is made of three components water salt and FDA medical grade silicone Its innovative design has two chambers an inner chamber filled with pure water and an outer chamber filled with salt water When the Chemo Mouthpiece is put in a standard freezer the inner pure water chamber will freeze solid but the outer salt water chamber will not The outer salt water chamber stays ice cold which allows the mouthpiece to cool a patient s oral cavity The left image below shows heat distribution before Chemo Mouthpiece was administered and the right shows after The lighter colored areas indicate the highest temperatures and the dark show the lowest As shown in these thermographic images the entire oral cavity is cooled completely with Chemo Mouthpiece Before After Images certified by thermographer Julie Conner CCT 2017 Data on File What is ORAL MUCOSITIS Chemotherapy and radiation can cause oral mucositis and ice chips are commonly used as a preventative method Chemo Mouthpiece is a more efficient option than ice as it cools the whole oral cavity not just the bottom half Oral cryotherapy used during treatment reduces blood flow by narrowing the blood vessels called vasoconstriction which limits the amount of drugs delivered to the oral cavity tissues Stopping the toxic drugs from reaching the gums and mouth may help with oral mucositis There are large bodies of data supporting the use of oral cryotherapy with many citing a notable reduction in the severity of oral mucositis Some of the most respected organizations have made recommendations based on this data A few of these very well known groups endorsing the use of oral cryotherapy when treated with mucotoxic agents are Oncology Nursing Society ONS National Comprehensive Cancer Network NCCN and Multinational Association of Supportive Care in Cancer MASCC Intraoral scanning has shown Chemo Mouthpiece will cool the gums tongue and palate entire oral cavity uniformly which is best for prevention This brochure is for informational purposes only and is subject to change at any time ORAL HYGIENE It is especially important to take proper oral care before and during treatment For best results practice good oral hygiene In addition to using the Chemo Mouthpiece during your cancer treatments or as often as needed during the day for pain relief following a protocol for good oral hygiene is recommended Your nurse oncologist or oral care team can give you strategies to follow but below are some points to remember and practice daily Outer clear chamber filled with salt water Inner blue chamber filled with fresh water Practice good Oral mucositis refers to redness swelling and sores inside the mouth It is a significant health issue for cancer patients undergoing chemotherapy or radiation and is cited as the most troubling side effect by more than 40 of patients The incidence and severity of oral mucositis varies depending on the treatment regimen and modality hh Visit your dentist prior to commencing cancer therapy hh Rinse your mouth frequently with warm salt water or a baking soda rinse hh Inspect your mouth daily for red spots or sores hh Use a soft bristle toothbrush hh Do not use dental floss if your gums are tender hh Avoid using mouthwashes that contain alcohol hh Do not use tobacco products or drink alcohol hh Avoid spicy foods and foods that are hard to chew hh Drink at least eight glasses of water daily The sores or ulcers caused by oral mucositis can become infected by bacteria viruses or fungi The resulting pain can make it difficult for patients to eat which could lead to weight loss or overall disparagement of health The pain has often been described as a burning sensation much like a sunburn on the inside of the mouth Symptoms are characterized by redness swelling dry mouth and open sores or ulcerations These symptoms can make it extremely difficult for patients to eat drink swallow speak or even sleep normally Patients suffering from oral mucositis may also require high doses of analgesics longer hospitalization and intravenous feeding to receive nutrition and maintain proper hydration Patients who develop oral mucositis are several times more likely to have unplanned breaks in their treatment and are also more likely to be hospitalized due to complications If symptoms become severe cancer treatment may have to be delayed dose reduced or even terminated which potentially reduces the likelihood of recovery Pictured is a patient suffering from oral mucositis with visible mouth sores and swelling

ICE PACK FOR INSIDE THE MOUTH FOR Chemo Mouthpiece FEATURES BENEFITS Cools the entire oral cavity Stays ice cold for 30 minutes No Rx required a drug free solution Developed for Cancer Patients by a Cancer Survivor ORAL MUCOSITIS FSA HSA eligible Single patient multi use Easily cleaned with soap and hot water One size fits most adults Comes with a convenient insulated cooler and carrying bag for travel Can be used by patients with sensitive teeth Excellent alternative to ice chips Made of FDA medical grade silicone water and salt AVAILABLE ONLINE ORDER TODAY Helping Patients Manage Oral Mucositis HOW TO ORDER Visit chemomouthpiece com and enter the code below for off and free shipping CMP5 CHEMO MOUTHPIECE LLC 10 Railroad Avenue Closter NJ 07624 USA 1 201 716 0693 inquiries chemomouthpiece com chemomouthpiece com

ICE PACK FOR INSIDE THE MOUTH FOR Chemo Mouthpiece FEATURES BENEFITS Cools the entire oral cavity Stays ice cold for 30 minutes No Rx required a drug free solution Developed for Cancer Patients by a Cancer Survivor ORAL MUCOSITIS FSA HSA eligible Single patient multi use Easily cleaned with soap and hot water One size fits most adults Comes with a convenient insulated cooler and carrying bag for travel Can be used by patients with sensitive teeth Excellent alternative to ice chips Made of FDA medical grade silicone water and salt AVAILABLE ONLINE ORDER TODAY Helping Patients Manage Oral Mucositis HOW TO ORDER Visit chemomouthpiece com and enter the code below for off and free shipping CMP5 CHEMO MOUTHPIECE LLC 10 Railroad Avenue Closter NJ 07624 USA 1 201 716 0693 inquiries chemomouthpiece com chemomouthpiece com