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CONGRESS Congress 2017 Congress 2017 21st 24th March 2017 www iat org uk 2017 21st 24th March 2017 Animal Technology underpinning scientific knowledge

Contents General Information Contacts 2 Welcome from the Congress Committee 5 General Information 7 Education Drop In Session 11 Animal Technology and Welfare Journal Prize 2016 15 Andrew Blake Tribute Award 2017 16 20 AAALAC International Fellowship Award IAT Annual General Meeting Agenda 25 27 Life and Honorary Members AAALAC International Fellowship Award UK Applications 29 London Branch Charity 2017 AS ET 30 Motor Neurone Disease North East Branch Charity 2016 33 23 Index to Advertisers Sponsorship 62 Scientific Programme At A Glance Summaries Tuesday Wednesday and Thursday 35 Workshop Sessions Tuesday 39 Platform Programme and Workshop Sessions Wednesday 42 Platform Programme Thursday 48 55 Kevin Dolan Memorial Lecture Poster Presentations 56 Poster Displays 59 Workshop Sessions 67 Social Programme 78 Events and Entertainment Trade Exhibition Exhibitors Index and Exhibition Plan Exhibiting Companies 80 82 Animal Technology underpinning scientific knowledge The IAT roundel logo is a registered trademark of the Institute of Animal Technology

Congress 2017 Contacts During Congress the Committee can be contacted via the Congress Reception After Congress contact should be made via email to congress iat org uk Registered Office Institute of Animal Technology 5 South Parade Summertown Oxford OX2 7JL UK Copyright Institute of Animal Technology 2017 All rights reserved no part of this handbook may be reproduced by any means without prior written permission of the Institute of Animal Technology and the Publisher Reproduction in whole or part without the express written permission of the copyright holders is prohibited This HANDBOOK is highly confidential Please DO NOT leave it unattended during Congress All information contained is correct at the time of going to press Published on behalf of IAT Congress 2017 by PRC Associates Ltd Designed and Printed in Great Britain Congress 2017 Animal Technology underpinning scientific knowledge 2 General Information

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Welcome Welcome from the Congress Committee Welcome to Congress 2017 and Croeso i Celtic Manor On behalf of the IAT we hope you find your time at Congress to be rewarding and enjoyable Every year we send out feedback forms to all delegates on their return from Congress and utilising one venue is always given high priority by respondents This year we have secured the services of Celtic Manor with all events and accommodation taking place under one roof We hope you approve Details of exactly where in the venue events are taking place can be found both in this Handbook the Notepad and also on the new IAT Congress App If you haven t already downloaded the App please ask at the Congress Reception or see the information on page 22 giving more details The AGM will be held at 18 00 on Tuesday 21st March full details are on page 25 in the Beaumaris Suite convention level C2 followed by a wine reception and buffet dinner served in the Trade Exhibition Hall Foyer The Scientific Programme is once again full and varied This year sees an unprecedented number of First Time Presenters with six participants making their debuts We do encourage you to come along and support them Feedback from Congress 2016 indicated that the introduction of more Workshops on Tuesday afternoon and Wednesday was very well received There were issues around full attendances and registration for the Workshops which we hope have been addressed this year Online registration was launched in January with places released over the three months leading up to Congress As in previous years there will be an Education Drop in Session on the IAT stand during the morning coffee break on Thursday 23rd March If you have any questions relating to the IAT qualifications CPD or would like to find out more about what the IAT can offer then please come along for an informal chat The largest Trade Exhibition of its kind in the UK takes place at Congress Lunches as well as refreshment breaks will be served in the Trade Exhibition Hall Foyer Thanks to the generous support of the exhibiting companies the competition to win iPads now in its sixth year will be run Your Passport to enter is in your delegate bag and more information appears on pages 8 and 112 Within the delegate feedback there was great demand for the now legendary Quiz Night We will be using the Caernarfon Suite for this so there is no restriction on numbers attending There will be a disco for those who don t wish to test their knowledge on a wide range of topics including wine If you should have any queries or issues during Congress please speak to a member of the Congress Committee The Congress Committee can only help if they know there is a problem If you have any ideas or comments regarding any aspect of Congress after the event please contact the Congress Committee via email at congress iat org uk We wish you a very enjoyable Congress 2017 and thank everyone for their sustained valued support which enables the Institute to continue to deliver services to our members and the wider scientific community IAT Congress Committee General Information 5

General Information THE VENUE This year ALL delegates will be accommodated under one roof with all activities taking place within the main convention venue Further details and timings are contained in this Handbook Please note that the check in time for the hotel is 16 00 and check out is 11 00 Useful location maps can be found in the Notepad CONGRESS RECEPTION On Tuesday 21st March the Congress Reception will be located in the Hotel s Main Foyer It will then relocate to the Trade Exhibition Hall Foyer for Wednesday and Thursday Opening hours Tuesday 21st March Wednesday 22nd March Thursday 23rd March 10 00 17 45 08 00 17 00 08 00 13 00 FIRST TIME AT CONGRESS Or would you just like to know where you are going Then come along to the Congress Reception and just ask ORIENTATION TOUR and ICE BREAKER On Tuesday 21st there will be an Orientation Tour starting from the Congress Reception at 16 45 and the Ice Breaker session will follow at 17 00 in the Beaumaris Lounge convention level C2 Come along and join us to get to know your way around and meet fellow delegates Those attending Workshop sessions are most welcome to join the Ice Breaker convention level C2 once their Workshop has finished Grateful thanks to DBM Scotland who are very kindly sponsoring this session again MEALS Breakfast 07 00 09 00 07 00 09 30 Wednesday and Thursday Friday Buffet Lunch 12 45 14 15 12 45 14 00 Wednesday Thursday Lunch on both days will be served in the Trade Exhibition Hall Foyer convention level C On Tuesday evening dinner will be served in the Trade Exhibition Hall Foyer at 19 00 This will be a buffet dinner with a wine reception marking the official opening of the Trade Exhibition General Information 7

General Information Dinner on Wednesday evening will be served at 19 30 in the Caernarfon Suite convention level C1 This will be followed by a Quiz Night and Disco We are most grateful to Tecniplast for their kind sponsorship of the Quiz The Gala Dinner Dance on Thursday evening will start at 20 00 and is also being held in the Caernarfon Suite convention level C1 Please note that the dress code is smart no jeans or trainers please Gentlemen should wear jackets and ties Gala Dinner Ticket You will find your ticket for the Gala Dinner INSIDE your Delegate badge Exhibiting companies will sometimes invite you to join their table for the Gala Dinner and in this instance you should hand them your ticket so they can reserve a place for you If you do not wish to join an exhibitor s table or if you have come to Congress on your own and are unsure of where to sit please see a member of the Congress Committee prior to Thursday lunchtime who will be happy to help you find a seat Table plans for the Gala Dinner will be available at the Congress Reception from 10 30 on Wednesday coinciding with the morning coffee break AGM The 31st Annual General Meeting of the Institute of Animal Technology will be held on Tuesday 21st at 18 00 in the Beaumaris Suite convention level C2 A full Agenda appears on page 25 and attendance is open to ALL delegates TRADE EXHIBITION The Trade Exhibition is situated on convention level C Opening times Tuesday Wednesday Thursday are 19 00 22 30 Official opening 09 30 17 30 09 30 14 30 Congress 2017 Trade Competition Not one BUT TWO CHANCES to WIN an iPAD For the 6th successful year the Exhibitors have worked with the Congress Committee to offer a great competition so don t miss out on the chance to WIN AN iPAD There are TWO on offer one exclusively for First Time Delegates and the other is open to All Delegates See the instructions on page 112 and make sure you are CARRYING your PASSPORT AT ALL TIMES when you visit the EXHIBITION HALL Good Luck 8 General Information

General Information TEA AND COFFEE Refreshments will be served in the Trade Exhibition Hall Foyer convention level C at the following times Wednesday Thursday 10 30 11 00 and 15 00 16 00 10 30 11 15 and 15 45 16 15 LECTURES AND PAPERS The Platform Programme will be held in the Caernarfon Suite convention level C1 Please refer to pages 35 to 55 within the Scientific Programme section for all information on the Paper Presentations The Kevin Dolan Memorial Lecture will be given by Julie Keeble on Thursday at 16 15 The abstract for her paper entitled Animals that are out of this world can be found on page 55 Kevin Dolan 1926 2011 When Kevin Dolan died in 2011 at the age of 85 IAT Council wished to honour his memory in gratitude for the contribution he had made to Animal Technologists and the industry in general and therefore fittingly the Special Guest Lecture given annually at Congress was renamed the Kevin Dolan Memorial Lecture Kevin s contributions to the IAT included services on Council and for several years he was Editor of the IAT Journal only standing down on his retirement He received his Fellowship in 1977 at the same time as attaining a Diploma in Law He was also made a Vice President of the IAT and latterly an Honorary Member He also authored many distinguished books and articles on the subject of law and ethics using animals in science but it was as a teacher that Kevin had most impact He taught on the Postgraduate Diploma MSc course the Medical Technology courses at City of Westminster and on Personal Licence Modular training courses To paraphrase one of his students Kevin was a great teacher because he was passionate about the subject he was dealing with and the people he was teaching to Despite joining the world of animal technology somewhat later in life after many years in the ecclesiastical domain Kevin s impact on our industry was outstanding His was a life well lived in the service of others and in recognition is remembered at Congress POSTERS All Posters will be displayed on Tuesday Wednesday and Thursday in the Trade Exhibition Hall Foyer convention level C Our thanks go again to LBS Serving Biotechnology Ltd who generously continue to sponsor the award for the Best Poster Further details under Prizes and Awards Meet the Poster Authors all poster authors will be in attendance at their posters to answer questions during Wednesday Thursday 13 00 13 45 15 45 16 15 General Information 9

General Information Four Poster Presentations will also take place on Thursday 15 00 15 45 in the Caernarfon Suite convention level C1 Ultrasonic vocalisation as a measure of positive welfare in rats Tim Jones DSTL Porton Down Creatively meeting the standards taking rabbit housing to the next level Katherine Marshall Oregon Health and Science University Advances in welfare and scientific outcomes of the bile duct cannulated rat model utilised in absorption distribution metabolism and excretion ADME studies Hans van Wijk Covance Laboratories A method for repeated dosing of juvenile mice via oral gavage Peter Paccagnini Sequani Ltd A schedule and synopsis of each presentation appear on page 56 onwards Abstracts of the other poster displays follow on page 59 WORKSHOPS ALL Ten Workshops taking place on Tuesday and Wednesday have been prebooked online prior to Congress Everyone who has registered must confirm their attendance at the Congress Reception A timetable and reviews on each workshop and presenter appear on page 67 onwards in this Handbook Abstracts also appear in the main programme All workshops are IAT CPD credited R C Hartelust bv P O Box 2170 5001 CD Tilburg The Netherlands Tel 31 13 4555189 Fax 31 13 4550175 E mail info hartelust net Macaca fascicularis Macaca mulatta Beagle dogs Purpose bred for research use Health screened for a range of organisms Quarantined before shipment Full documentation with every delivery Direct delivery in own vehicle Prices and terms request 10 General Information

General Information Workshop 1 How to be an AWERB champion Penny Hawkins RSPCA Workshop 2 Working with minipigs all you ever wanted to know Adrian Zeltner Ellegaard G ttingen Minipigs Workshop 3 Introduction to Zebrafish Danio rerio Jon Faupel and Tommaso Sala Tecniplast Workshop 4 Practical aseptic technique basic and advanced Olga Woolmer and Alexandros Zervas Royal Veterinary College Workshop 5 Severity classification and reporting Kathy Ryder Home Office Workshop 6 Preparing to present for the first time Diana Baumann Stowers Institute Workshop 7 Using the science of human behaviour to improve animal welfare Suzanne Rogers Human Behaviour Change for Animal Welfare Community Resource Workshop 8 I VC environmental health monitoring 3Rs and colony management Patrick Hardy and Pete Willan Allentown Workshop 9 Playtime for rats Kathryn Owen NC3Rs Workshop 10 Nice to meet you so what do you do for a living Bella Williams and John Meredith UAR Education Drop In Session Thursday 23rd March 10 30 11 15 IAT FE and HE Qualifications Do you have any questions about the IAT FE and HE qualifications Do you want to find out more about what qualifications are available and how to take them Perhaps you have a query about exemptions or what the next step is for you Then please come along to this Drop In Session taking place at the IAT Stand situated in the Trade Exhibition Hall Foyer during the coffee break on Thursday morning and speak to Cathy Godfrey Chair of the Board of Moderators and Brian Lowe Course Director for HE courses There will also be representatives from CLAST College of Laboratory Animal Science and Technology who are now the providers of the IAT HE qualifications at their stand near the IAT stand They will be able to give more details on the HE courses available IAT courses are available as CPD courses and further details can be obtained from CLAST General Information 11

General Information PRIZES AND AWARDS The First Time Presenter Paper The annual Jack Mundy Prize has previously been awarded at Congress for the best paper given by a Junior Technician but in 2004 the competition was opened up to include anyone who is making their debut presentation at Congress We are particularly delighted this year to announce that Six First Time Presenters will participate from 09 30 on Thursday and also that Marshall BioResources maintain their sponsorship with a generous monetary gift of 200 00 The winner will be announced at the Awards Ceremony on Thursday afternoon Arthur Edward Jack Mundy FIAT was thought of by his peers as the founder of the Animal Technicians Association ATA in 1950 During the early years as Honorary Secretary he worked very hard to make the Association work and raise the original membership of 200 By 1960 it had doubled to 400 members When the Laboratory Animal Centre LAC discontinued their support of an annual Congress it was Jack who petitioned for the ATA to take over and he organised the first one in Bangor with the help of his wife Mimi The following year it was held at the Royal Veterinary College where he worked as Chief Technician and there were two exhibitors When the organisation became too big for two people to manage the Congress Committee was formed On his retirement Jack was awarded Life Membership of the IAT Best Poster A selection panel nominated by the Congress Committee judges each poster according to the criteria for best content clarity and quality of science Criteria improvement in animal welfare innovation ease of replication of work presentation and layout The prize is a generous cash award of 200 00 and our thanks go again to LBS Serving Biotechnology Ltd for their support The winner will be announced at the Awards Ceremony on Thursday afternoon 12 General Information

Learning Curve Goes from Strength to Strength Learning Curve welcomes Dr Angela Kerton BVetMed Cert LAS MRCVS to the most trusted and experienced training team as Executive Director Angela Kerton graduated from the Royal Veterinary College in 1995 being awarded the Waltham medal for the best final year elective project involving a laboratory animal science study On graduation Angela worked for the small animal charity the PDSA in the East End of London as a general small animal practitioner for six years She joined the CBS department at Imperial College London and was appointed as Named Veterinary Surgeon in 2003 leading a team of veterinary surgeons to share best practice and promote the 3Rs As head of training she was responsible for monitoring and developing training programmes at Imperial College This involved the direction and participation in mandatory UK Home Office Module courses including Project Licence training Angela was instrumental in the design and delivery of animal husbandry advanced anaesthesia and telemetry training modules Angela s ability to provide high quality teaching has received excellent feedback from students she particularly enjoys the creative aspect of teaching sourcing new materials devising interactive programmes and developing new methods of making learning interesting and keeping learners engaged She is both section convenor for the Laboratory Animal Science Association LASA Care and Welfare Section and the Education Training and Ethics Section Based upon her reputation and experience she is a highly sought after conference speaker and has also taught on the MSc courses in Immunology Genes Drugs and Stem Cells during the past two years at Imperial College During the fifteen years she has been a NVS she has worked tirelessly to harmonise course content facilitate veterinary researcher collaboration and promote and enable the practical uptake of the 3Rs In 2015 Angela was awarded the 3Rs lifetime achievement Provosts award for excellence in animal research at Imperial College I am sure that Angela s experience knowledge enthusiasm and vision will be great assets to The Learning Curve in providing excellent training and CPD to the scientific and veterinary community Martin Heath MSc FRSB FIAT FIScT PTLLS RAnTech Managing Director We have your future at heart

General Information Journal Article Marjorie Sandiford Whittingham Prize 2016 Animal Technology and Welfare Congratulations go to Tania Boden and Penny Hawkins for their winning 2016 paper selected by the Editorial Board Communicating the Culture of Care how to win friends and influence people published in the December 2016 issue of Animal Technology and Welfare Volume 15 No 3 Tania and Penny will be presented with their plaque at the Awards Ceremony on Thursday afternoon About the authors Tania is a principle Scientist for UCB Celltech whose company motto is Everything we do starts with a simple question how can we create more value for people with severe diseases She has previously contributed to ATW as part of the RSPCA UFAW Rodent Welfare Group with a submission entitled refining rheumatoid arthritis a joint approach UCB s goal is to command a leading position in discovering and developing new therapies to treat seriously ill patients focussing on neurological and immunological diseases to provide new treatments for specialists and their patients Penny is committed to promoting the application of the Culture of Care in practice as part of the RSPCA s work to reduce the conflict between animals and science She values the expertise and commitment of Animal Technologists very highly and has a long history of working with the IAT and its members to help promote laboratory animal welfare and ensure that the Culture of Care is more than just a buzzword Penny wants to see more Animal Technologists getting involved with their AWERBs and helping to shape their local cultures and she is really delighted to share the award with Tania during Tech Month Marjorie Sandiford Whittingham was a late arrival on Council in 1966 serving 11 years until she retired from work in the late 1970s For the 7 years prior to her retirement she was Secretary to the Institute and was also a Member of the Exam Board for all of those 11 years Marjorie s husband Dick Whittingham and Council set up the prize fund after her untimely death in Kenya where they had retired to The enormity of the amount of work that Marjorie completed during that period made her shorter service even more exceptional General Information 15

ANDREW BLAKE TRIBUTE AWARD 2017 ANDREW BLAKE TRIBUTE AWARD We all have a responsibility for the welfare of the animals in our care and it is often the little things that make a significant difference The Andrew Blake Tribute Award is awarded by the Institute of Animal Technology and sponsored by The Association of the British Pharmaceutical Industry the ABPI to an Animal Technologist at any level judged to have made a significant contribution to improving laboratory animal welfare Nine applications were received and the judges were impressed with all of the refinements presented The 2017 worthy winner is J ohn Waters BSc Hons MIAT NACWO Mammalian Behaviour and Evolution MBE Group Institute of Integrative Biology University of Liverpool Leahurst Campus Neston Cheshire CH64 7TE For his paper Time for change practicalities of implementing non aversive methods for handling mice One judge s observation included that this had massive potential impact on welfare and science John will present his paper after the First Time Presenters session at 12 15 on Thursday He will receive an engraved glass plaque and a total cash award of 250 00 at the Awards Ceremony prior to the Close of Congress on Thursday afternoon A full transcript of his presentation will appear in the April 2017 issue of Animal Technology and Welfare Volume 16 No 1 ANDREW BLAKE TRIBUTE AWARD SPONSORED BY THE ABPI 16 General Information

ANDREW BLAKE TRIBUTE AWARD 2017 The Andrew Blake Tribute Award commemorates the work and life of Andrew Blake who suffered from Friedrich s ataxia a hereditary condition described as one of the worst of neurological diseases Andrew died in May 2002 aged 39 Andrew was passionate about the need to support scientists in their work and his commitment to speaking out against animal rights activists took up much of the last ten years of his life He died shortly before he was to collect his MBE About the author John s career working with animals started at Liverpool University Medical School in 1990 as a trainee technician He gained his Membership Exam and a HNC in Life Sciences before moving to Liverpool School of Tropical Medicine to work with the Squirrel Monkey colony attaining a HNC in Biology in 1997 and then completing a degree in Zoology in 2000 In 2001 he moved to the Leahurst Campus as a senior technologist and after gaining NACWO status became the Chief Technologist John plays an active role in the AWERB for Liverpool University The work he is primarily involved in is behaviour and welfare communication and mate choice in wild mice He is responsible for all animal related duties and in charge of a small team of dedicated Animal Technologists John s main interest is animal welfare which he is keen to endorse and he has played a major part in promoting non tail methods of handling mice His main role now is to instruct fellow technologists in best practice for carrying out new methods of handling as he feels that by sharing this work and the associated perceived difficulties it will lead to others implementing the University s method which can only be a positive step for improving mouse welfare throughout the world Outside of work apart from following Liverpool Football Club John s main interests involve animals He breeds and races pigeons and is Vice President of the Royal Racing Pigeon Association Western Region General Information 17

General Information AAALAC International Fellowship Award Stephen Woodley MIAT RAnTech 2016 UK Recipient Stephen currently serves as Site Manager of the Biological Services Guy s Campus King s College London where he has management responsibilities for three animal research facilities including a state of the art fish facility 38 biological services staff 60 projects and 700 personal license holders on the Guy s Campus Prior to joining King s College Stephen worked for University College London s Institute of Ophthalmology and Institute of Neurology in a variety of technician and management positions He is a qualified and experienced Named Animal Care and Welfare Officer NACWO and has been an IAT Registered Animal Technologist RAnTech since 2012 receiving a level 3 National Diploma in Animal Technology MIAT from the Institute of Animal Technology Previously he acted as Named Training and Competency Officer NTCO during 2013 2015 Stephen is currently the Named Information Officer NIO and is studying for his IAT Higher Education qualifications Read a full account of his two week experience in America last October in the February issue of IAT Bulletin 53 2 Details to apply for the 2017 UK Award can be found on page 29 20 General Information

General Information AAALAC International Fellowship Award Katherine Marshall BS CMAR CVT RLATG 2017 USA Recipient We cordially extend a warm welcome to Kati who is the Resource Manager at the Oregon Health and Science University where she has been working since 1996 starting as a Laboratory Animal Technician Kati is passionate about the pursuit of continuing education by supporting training programmes and public outreach initiatives that relate to the care quality and humane treatment of laboratory animals She prides herself as a compassionate member leader and role model within the laboratory animal community through educating and mentoring her staff She is also an active leader within her local and regional laboratory animal science communities Within the Oregon branch of AALAS she served two 3 year terms as president elect president and past president She has also been an active participant in many of the branches educational and social outreach activities by presenting posters and helping with the organisation of key events Kati is also one of the Poster Presenters on Thursday Her poster is entitled Creatively meeting the standards taking rabbit housing to the next level so please go along to say hello to her when all the poster authors are in attendance and support her and the other three presenters on Thursday afternoon starting at 15 00 in the Caernarfon Suite The AAALAC pin in recognition of this honour will be presented to Kati at the Awards Ceremony on Thursday afternoon and she will also give a brief address on her experiences in the UK General Information 21

General Information CONGRESS APP Our new Congress 2017 App allows delegates to plan their scientific attendance interact with each other and provides all the details needed to enjoy the Congress experience 22 General Information

General Information CONGRESS BADGES It is important that you wear your badge at all times within the conference venue You will not gain access to the Exhibition Hall Papers Posters and Workshops if you are not wearing it Please also make sure you are wearing it at meal times and for all of the social events If you are not wearing it admittance will be refused We do however recommend you remove your badge when you leave the conference venue but please remember it for evening functions If you lose your badge please report your loss immediately to a member of the Congress Committee MOBILE PHONES AND PAGERS Out of courtesy to speakers and other delegates pagers and mobile phones must be switched off or put on non audible alerts BEFORE entering the main lecture theatre and the areas hosting the posters and workshops Mobile phones and mobile phone cameras MUST NOT be used in any of the scientific sessions at Congress ENQUIRIES If you have any questions or comments regarding Congress please direct them to the Congress Reception INDEX TO ADVERTISERS Page Allentown Europe 18 19 Page LBS OBC a tune software AG 53 Learning Curve Development Ltd 13 Bell Isolation Systems 38 NKP Isolators and Caging Systems IBC Bioquell UK Ltd 66 R C Hartelust bv Castium Ltd 41 Ortner Cleanroom Technology GmbH 26 Charles River 28 SAFE 14 Contec 34 Datesand Ltd IPS Product Supplies Ltd IFC 3 Special Diets Services 10 6 Transnetyx 4 24 General Information 23

Notice of AGM THIRTY FIRST ANNUAL GENERAL MEETING OF THE INSTITUTE OF ANIMAL TECHNOLOGY To be held on 21st March 2017 in the Beaumaris Suite convention level C2 AGENDA 1 Apologies for absence Minutes of the 30th Annual General Meeting held on Tuesday 8th March 2 2016 3 Matters arising from the Minutes as published in full on the Members section of the IAT website and in abridged form in the Bulletin Volume 52 No 6 4 Correspondence 5 Annual Report Council Objectives 6 Financial Report 7 Appointment of the Auditor 8 Election of Officers i President ii Vice Presidents iii Council 9 Proposals for Life and Honorary Membership 10 Presentation of Honorary Membership 11 Any other business Ken Applebee Chair of Council Linda Horan Honorary Secretary THE AGM IS OPEN TO ALL DELEGATES Voting rights are restricted to voting members only COUNCIL ELECTIONS 2017 There were ten nominees for nine vacancies on Council and therefore a ballot took place The nominees were as follows 1 Ken Applebee 6 Lynda Westall 2 Charlie Chambers 7 Matt Bilton 3 Alan Graham 8 Sam Jameson 4 Linda Horan 9 Kally Booth 5 Adele Kitching 10 Sylvie Mehigan General Information 25

IAT LIFE AND HONORARY MEMBERS HONORARY FELLOWS The Council may elect as an Honorary Fellow any member who in the opinion of the Council shall have given long and valuable service in the interests of the Institute An Honorary Fellow shall be entitled to enjoy all the privileges of a Fellow for so long as he she shall remain a member of the Institute but shall not be required to contribute to the funds of the Institute except in the case of a winding up No more than two Honorary Fellows shall be elected in any one calendar year We are delighted to announce that Professor Paul Flecknell was awarded Honorary Fellowship of the Institute in December 2016 and will be presented with his plaque at the AGM on Tuesday evening Paul Flecknell MA VetMB PhD DECLAM DLAS DECVA Hon DACLAM Hon FRCVS Paul has been a laboratory animal veterinarian for almost 40 years and spent most of that time working on pain assessment pain alleviation and laboratory animal anaesthesia having qualified from The University of Cambridge and completing his PhD at The University of London He has also been developing teaching and training resources for the past 30 years Paul commenced a long association with the IAT when working for the MRC where he taught on the Animal Technology courses at Paddington Technical College He attended the first of many IAT Congresses a few years later running anaesthesia workshops He was elected as a Vice President of the Institute and has continued to work to promote the role of Animal Technologists in the UK and elsewhere Most recently he became a trustee of CLAST and is also involved in the delivery of one of the course modules Paul steps down as Director of the facilities at The University of Newcastle this year but will continue to teach and develop e learning materials General Information 27

Call for nominations now open for the popular 2017 AAALAC International Fellowship UK Award If you are an IAT Registered Technologist RAnTech apply today Deadline is 1 June 2017 The AAALAC International Fellowship recognises two outstanding individuals one IAT Registered RAnTech and one AALAS Registered RALAT RLAT RLATG CMAR who have made or have the potential to make significant contributions to the field of laboratory animal care and use This Fellowship is valued at more than 3 000 The UK winner will receive a week long guest visit to a prestigious biomedical research facility in the USA this Autumn plus complimentary attendance at the National AALAS Meeting the USA s largest laboratory animal science and technology meeting being held in Austin Texas All registration travel accommodation meals and out of pocket expenses are covered receipts are required TO APPLY rite a brief letter nominating yourself or have someone write this letter on your 1 W behalf Stuart Stevenson BSc FIAT RAnTech won in 2013 2 Include a 500 word written statement describing why you should be selected 3 Include a copy of your CV 4 Include no more than three letters of support TIPS Be sure to address these points in your application l What have you done to promote animal welfare and refinement in your workplace i e involvement in AWERB training others advising on refinement etc hat have you done to promote animal welfare and refinement outside of your lW workplace i e IAT activities school visits public presentations etc ow have you shared your knowledge of laboratory animal care with others lH i e lectures posters workplace projects etc l If you are selected how will this award benefit your career and your associates Lynda Westall BSc Hons DMS FIAT RAnTech the 2014 UK winner l How will you translate this experience back to your workplace and your local association l Does your package include evidence of leadership or leadership potential and participation with posters presentations or publications l Have you participated in overseas meetings in the past Awardees are expected to share their experiences briefly by preparing a written report for AAALAC International and a full report for publication in the IAT Bulletin Awardees are also expected to communicate their experiences to peers by presenting at a local or national conference i e branch meeting or Congress Mail fax or email your application materials by 1 June 2017 Sylvie Mehigan MIAT RAnTech won in 2015 AAALAC International c o The International Fellowship Committee 5205 Chairman s Court Suite 300 Frederick MD 21703 United States Fax 301 696 9627 Email fellow aaalac org For complete details and a list of selection criteria visit www aaalac org about fellowship cfm Receipt of application will be confirmed by email to candidates by 6 June 2017 If you have not received confirmation or have any questions about this award please call 301 696 9626 or email fellow aaalac org The AAALAC International Fellowship Award is presented by AAALAC International through grants from Priority One Services Inc and Datesand Group Ltd in cooperation with AALAS IAT MRC and NIH Don t delay get your application in now Congratulations to Stephen Woodley MIAT RAnTech current 2016 winner General Information 29

2017 CHARITY NOMINATED BY the London Branch AS ET is a charity that has the objective of advancing education and promoting excellence in the care and welfare of animals used in science The United Kingdom leads the world in biomedical research much of which involves the use of animals The welfare of the animals and the value of the animal research both rely on highly educated and trained animal technical staff AS ET exists to ensure that access to high levels of education and training are available to all Animal Technologists who want to increase their qualifications or update their knowledge AS ET seeks to do this in the following ways l providing bursaries for a course connected with their work and cannot receive funding elsewhere l sponsoring conference sessions training seminars and the development of new courses l providing special bursaries and prizes to encourage involvement in educational activities www as et org uk Patron Professor Lord Naren Patel KT Chair of Trustees Professor Sir Richard Gardner FIAT Hon FRS Secretary to the Trust Ken Applebee OBE FIAT FRSB Trustees Stephen Barnett MSc FIAT Hon FRSB Jasmine Barley MSc FIAT Karen J Gardner Registered Charity Number 1133119 Registered Office 5 South Parade Summertown Oxford OX2 7JL

Examples of AS ET Grants CPD Courses In the last few years AS ET has awarded 16 grants for people to follow on a number of short courses e g animal behaviour experimental design Zebrafish animal genetics cryopreservation licensee and NACWO training Jamie Galvin recipient of the first AS ET bursary at a primate course Courses Leading to Qualifications Over the same period AS ET awarded bursaries to 25 people to assist payment of fees for the IAT qualifications in Laboratory Animal Science and Technology Twenty of these awards were for higher education courses Further details on applying for bursaries can be found on our website and or by visiting our stand Fund Raising Like all charities AS ET needs to raise money in order to carry out our work Generous corporate sponsors and official supporters provide much of our income but fund raising activities play an increasingly important role in boosting our funds One of the most important events in the AS ET year is the Annual Lecture where we ask a distinguished scientist to lecture on their subject in a way that will interest a general audience The 2016 lecturer was IAT President Professor Robin LovellBadge FRS This event raises finance by making a modest ticket charge and for the wine reception afterwards Professor Robin Lovell Badge FRS AS ET 2017 Annual Lecturer answering a question from Lecture Chair Terry Priest MBE Many individuals and IAT Branches support AS ET The West Middlesex Branch have made very generous and regular donations Others that have raised money for us include Cambridge Oxford Huntingdon and Ireland James Bussell on the finish line of the Great North Run Individuals have also done amazing things to boost funds In 2016 alone James Bussell at the Sanger Institute raised over a thousand pounds by completing the Great North Run and Jonathon Wood at Datesand raised 1 700 in a sponsored boxing match Jonathon Wood presenting Patron of AS ET Lord Patel with a cheque Professor Sir Richard Gardner FRS Chair of AS ET Trustees presenting representatives of the IAT West Middlesex Branch with a certificate to acknowledge their fund raising efforts on behalf of AS ET AS ET trustees are both delighted and grateful to be the beneficiary of the Congress 2017 Raffle and we extend our thanks to all those involved in organising it Please buy your tickets and also take part in the other AS ET fund raising activities at Congress The more money we can raise the more Animal Technologists we can help to improve their education and training ambitions General Information 31

General Information In 2016 the North East Branch nominated as their charity with the express wish that the funds raised at Congress last year were restricted to Research into MND Thank you to everyone who bought a raffle ticket raising 1K trator IAT Adminis imal Technology An Institute of rade 5 South Pa n Summertow Oxford OX2 7JL General Information 33

Scientific Programme TUESDAY 21st MARCH VENUE convention level c2 Time Event 10 00 Registration Opens WORKSHOP SESSIONS 12 15 14 15 W3 Introduction to Zebrafish Danio rerio Jon Faupel and Tommaso Sala 12 15 14 15 W8 IVC environmental health monitoring 3Rs and colony management Patrick Hardy and Pete Willan 14 30 16 30 W5 Severity classification and reporting Kathy Ryder 14 30 16 30 W9 Playtime for rats Kathryn Owen 16 45 Orientation Tour Meet at Congress Reception 17 00 Ice Breaker Session Beaumaris Lounge convention level C2 18 00 AGM Beaumaris Suite convention level C2 Scientific Programme 35

Scientific Programme WEDNESDAY 22nd MARCH VENUE caernarfon suite Time Event 09 00 09 05 Opening of Congress 2017 Alan Graham Chair Congress Committee 09 05 09 35 1 minute FLASH TRADE PRESENTATIONS PAPER SUMMARIES 09 35 10 05 Preparing dogs for study life improving welfare efficiency and data output Laura Scullion Hall 10 05 10 35 Refinement of food restriction regimes in mice David Thomson 10 30 11 00 COFFEE WORKSHOP SESSIONS 10 45 12 45 W1 How to be an AWERB champion Penny Hawkins 10 45 12 45 W3 Introduction to Zebrafish Danio rerio Jon Faupel and Tommaso Sala 10 45 12 45 W7 Using the science of human behaviour change to improve the welfare of research animals Suzanne Rogers 10 45 12 45 W8 IVC environmental health monitoring 3Rs and colony management Patrick Hardy and Pete Willan 12 45 14 15 LUNCH 13 00 13 45 MEET THE POSTER AUTHORS Trade Exhibition Hall Foyer WORKSHOP SESSIONS 13 15 15 15 W2 Working with minipigs all you ever wanted to know Adrian Zeltner 13 15 15 15 W4 Practical aseptic technique basic Olga Woolmer and Alexandros Zervas 13 15 15 15 W5 Severity classification and reporting Kathy Ryder 13 15 15 15 W10 Nice to meet you so what do you do for a living Bella Williams and John Meredith 15 00 16 00 TEA WORKSHOP SESSIONS 15 30 17 30 W1 How to be an AWERB champion Penny Hawkins 15 30 17 30 W4 Practical aseptic technique advanced Olga Woolmer and Alexandros Zervas 15 30 17 30 W6 Preparing to present for the first time Diana Baumann 15 30 17 30 W9 Playtime for rats Kathryn Owen 36 Scientific Programme

Scientific Programme THURSDAY 23rd MARCH VENUE caernarfon suite Time Event 09 00 09 30 The Home Office Update ASRU latest news Sue Houlton and Will Reynolds FIRST TIME PRESENTERS sponsored by Marshall BioResources 09 30 09 50 Light intensity and its impact on survival rates of pigmentless Zebrafish Danio rerio Paul Barwood 09 50 10 10 Refinement of tumour passage by optimisation of the tissue disaggregation protocol Melanie Galvin 10 10 10 30 Refinements in rat dual cannulation surgery by using the vascular access button offering the advantage of group housing Samantha Izzard 10 30 11 15 COFFEE FIRST TIME PRESENTERS sponsored by Marshall BioResources 11 15 11 35 Advances in transgenic technology Elizabeth Hurd 11 35 11 55 Working with poultry in avian viral disease research spreading our wings Megan Cooper 11 55 12 15 Focus on improving welfare reducing stress and aiding recovery of surgical procedures Emma Vacca 12 15 12 45 ANDREW BLAKE TRIBUTE AWARD sponsored by The Association of the British Pharmaceutical Industry Time for change practicalities of implementing non aversive methods for handling mice Winner John Waters 12 45 14 00 LUNCH PAPER SUMMARIES 14 00 14 30 Using the science of human behaviour change to improve the welfare of research animals Suzanne Rogers 14 30 15 00 You have the best ideas Norman Mortell 15 00 15 45 POSTER PRESENTATIONS sponsored by LBS 15 45 16 15 TEA 15 45 16 15 MEET THE POSTER AUTHORS Trade Exhibition Hall Foyer 16 15 17 00 KEVIN DOLAN MEMORIAL LECTURE ANIMALS THAT ARE OUT OF THIS WORLD Julie Keeble 17 00 17 15 Presentation of Awards First Time Presenter 2017 sponsored by Marshall BioResources Best Poster 2017 sponsored by LBS Journal Article 2016 Animal Technology and Welfare Marjorie Sandiford Whittingham Memorial Prize Andrew Blake Tribute Award 2017 sponsored by The Association of the British Pharmaceutical Industry AAALAC International USA Fellowship Award 2017 Close of Congress Ken Applebee Chair Institute of Animal Technology Scientific Programme 37

38 Scientific Programme Scientific Programme

Workshop Sessions TUESDAY 21st MARCH VENUE convention level c2 10 00 Congress Registration Opens WORKSHOP SESSIONS Further details appear on page 67 onwards 12 15 W3 Introduction to Zebrafish Danio rerio Jon Faupel BSc Hons 1 and Tommaso Sala 2 1 Aquatics Specialist and Account Manager Tecniplast UK Ltd BCM 3058 London WC1N 3XX 2 Customer Care Manager Aquatic Line Tecniplast SpA Via 1 Maggio 6 Buguggiate Varese 21020 Milan Italy The use of Zebrafish Danio rerio within research has increased year on year over the past two decades and is now ranked as one of the major species used The environment in which Zebrafish thrive is crucial and the Animal Technologist has a vital role in helping to sustain this This workshop aims to provide an introduction to Zebrafish and managing their welfare within a research environment The workshop will focus on An overview of Zebrafish their origins and general biology Zebrafish have become one of the most used animal models in research for a number of reasons but where do they originate from and how were they discovered as a successful biological model for research As Zebrafish are used by more and more facilities around the world an understanding of what they have to offer as a research model is required Basic husbandry housing and water quality Zebrafish require a stable environment with specific ranges of water quality as well as multiple feeds per day with different types of diet So what exactly is involved with the day to day husbandry As technology improves so do aquatic housing systems How were the first systems designed and what improvements have been made over the years to attain the highest level of welfare for aquatic species Ill health and disease prevention healthy fish lead to healthy science so it is imperative that everything that can be done to provide the best housing environment is implemented It is also highly important to understand the early warning signs of stressed fish and what can be done to minimise the stressing factors There are many common Zebrafish diseases that can impact on colonies within a facility so what signs present themselves and how are the fish affected Nutrition choosing the right diet and feeding regime can play a large part in the health and breeding potential of Zebrafish so it is important to understand what is available on the market and which types of diet provide the best nutritional value 12 15 W8 IVC environmental health monitoring 3Rs and colony management Patrick Hardy DVM DipECLAM Exec MBA1 and Pete Willan DMS FInstMgt MIAT RAnTech2 1 Director of Veterinary and Professional Services Allentown Inc 165 Route 526 Allentown New Jersey 08501 USA 2 Product Specialist UK and Europe Veterinary and Professional Services Allentown Europe PO Box 3056 Reading Berkshire RG1 9UY Combined advances and innovations in qPCR technology and in IVC exhaust sampling capture systems represent a major opportunity to improve very significantly the management of IVC environmental health monitoring HM at different levels Scientific Programme 39

Workshop Sessions TUESDAY 21st MARCH i mproving operational practicalities of sampling for HM i mplementing the 3Rs through a significant reduction of animal sentinel use i ncreasing the sensitivity and reliability of HM versus sentinel animals and soiled bedding transfer Comparative studies and field testing have allowed assessing the value of IVC environmental HM versus traditional sentinel based methods to be assessed The workshop will address the following topics l key objectives and principles of a HM programme design lp rinciples of PCR techniques versus other diagnostic assays including interpretation and limitations of results l l imitations of HM based on sentinel animals exposed to soiled bedding lp erformance of environmental health monitoring in IVC systems results from pilot and field multi centric studies l c onduct and practicalities of various environmental sampling methods for PCR at cage and rack level versus animal based sampling methods l c ross contamination control during sampling l c ontribution of environmental HM to the quality reliability of a HM programme including the implementation of FELASA recommendations to 3Rs implementation and also the cost practicalities of HM operational management l l l 14 30 W5 Severity classification and reporting Kathy Ryder MB BS BSc MRCP DPhil Inspector Animals in Science Regulation Unit Home Office 2 Marsham Street London SW1P 3DF To examine the process of assessing and reporting severity and examining the challenges of achieving consensus ASPA requires the classification of procedures according to severity during the application for a project licence There is also a requirement to report the actual severity experienced by each animal used in a procedure Both these processes provide opportunity to refine the adverse effects of procedures Consistency of assignment of severity categories across the UK is required so that information provided is accurate and usable Topics include l i dentifying the components within the procedures which may cause pain suffering distress or lasting harm ld efining the adverse effects and mitigation l i dentifying appropriate end points la ssigning prospective severity classification la udience response session Turning Point to consider examples of actual severity assessment 14 30 W9 Playtime for rats Kathryn Owen BSc Hons MRes PhD National Centre for the 3Rs NC3Rs Gibbs Building 215 Euston Road London NW1 2BE In 2017 the NC3Rs has decided to spotlight the welfare needs of the laboratory rat Together with AstraZeneca our workshop aims to explore approaches to providing laboratory rats with a complex environment and increased opportunity to exercise We will focus on how Animal Technologists can consider practical implementation within their institution Outputs from the meeting will include a short paper highlighting opportunities and barriers to adoption 40 Scientific Programme

Workshop Sessions TUESDAY 21st MARCH 16 45 ORIENTATION TOUR Meet at Congress Reception 17 00 ICE BREAKER SESSION Beaumaris Lounge convention level C2 18 00 AGM Beaumaris Suite convention level C2 Scientific Programme 41

Platform Programme and Workshop Sessions WEDNESDAY 22nd MARCH VENUE caernarfon suite 09 00 Opening of Congress 2017 lan Graham MA FIAT A Chair Congress Committee Chair P rofessor Robin Lovell Badge FRS President Institute of Animal Technology 09 05 FLASH TRADE PRESENTATIONS A selection of one minute talks on current industry innovations PAPER SUMMARIES 09 35 Preparing dogs for study life improving welfare efficiency and data output Laura Scullion Hall PhD University of Stirling Causewayhead Stirling Scotland FK9 4LA The dog is the preferred non rodent species in the safety assessment of new compounds Despite their wide spread use 100 000 used globally each year in research we know little about their welfare and the impact of routine practices on their welfare While some form of training is frequently recommended in legislation and guides there is very little guidance available on effective training protocols As a result many practices are based upon anecdotal evidence While there is a broad desire to implement effective training for many aspects of laboratory housed dog use there remain a number of barriers to uptake including lack of resources specific to the research environment lack of confidence in training techniques and concerns about interference with study outputs At the outset of a new collaborative project across UK industry we present evidence based resources for care technical and scientific staff to support the implementation of refinements Best practice for a number of protocols will be shared In this talk a number of techniques employed to prepare dogs for study life will be presented These include positive reinforcement training desensitisation increased predictability modified handling and modified dosing techniques Empirical evidence demonstrating both the welfare benefits and ease of implementation of an effective positive training protocol for laboratory housed dogs are described As with any planned refinement it is necessary to evaluate the effects of a training programme using a validated method We have developed welfare monitoring tools which can be employed by care staff and technical staff to monitor the impact of planned refinement on home pen welfare and to evaluate progress in training 10 05 Refinement of food restriction regimes in mice David Thomson PhD University of Strathclyde The Strathclyde Institute of Pharmacy and Biomedical Sciences 161 Cathedral Street Glasgow Scotland G4 0RE Food restriction is a well recognised method used in neuroscience to promote performance towards a goal and to increase reward seeking behaviour In the rodent a large number of behavioural tasks depend on appropriate balanced reduction of the rodent s food intake to maintain the animal s weight to within 85 90 of their free feeding weight It is well documented that the animals often do not perform the tasks as well on a Monday Our group uses refined 42 Scientific Programme

Platform Programme and Workshop Sessions WEDNESDAY 22nd MARCH food restriction methods to increase performance for behavioural tests such as recognition tasks and short term memory tasks both of which require increased goal seeking behaviour in order to examine disorders such as Schizophrenia and autism and its improved management This paper will describe issues that we have encountered and how we have developed a series of refinements such as group housing and changes to weekend food provision These changes increase the likelihood of reduced fluctuations in body weight that have an adverse effect on experimental data In part we have been able to implement this with the Animal Technologist s involvement in the weekend food restriction process From these refinements we have observed more sociable animals reduced weight fluctuations and improved returns on Monday training results 10 30 COFFEE TEA served in the Trade Exhibition Hall Foyer 10 45 WORKSHOP SESSIONS Further details appear on page 67 onwards 10 45 W1 How to be an AWERB champion Penny Hawkins BSc PhD Deputy Head Research Animals Department RSPCA Wilberforce Way Southwater West Sussex RH13 9RS Animal Technologists already act as valuable members of the Animal Welfare and Ethical Review Body AWERB and this workshop aims to encourage even more active participation It is suitable for those who are already AWERB members and others who are considering becoming involved Topics include l introduction to AWERB l helping the AWERB to fulfil all of its tasks l improving engagement with scientists l i dentifying training needs to help Animal Technologists become active and effective AWERB members l teaching styles 10 45 W3 Introduction to Zebrafish Danio rerio Jon Faupel BSc Hons 1 and Tommaso Sala 2 1 Aquatics Specialist and Account Manager Tecniplast UK Ltd BCM 3058 London WC1N 3XX 2 Customer Care Manager Aquatic Line Tecniplast SpA Via 1 Maggio 6 Buguggiate Varese 21020 Milan Italy The use of Zebrafish Danio rerio within research has increased year on year over the past two decades and is now ranked as one of the major species used The environment in which Zebrafish thrive is crucial and the Animal Technologist has a vital role in helping to sustain this This workshop aims to provide an introduction to Zebrafish and managing their welfare within a research environment The workshop will focus on An overview of Zebrafish their origins and general biology Zebrafish have become one of the most used animal models in research for a number of reasons but where do they originate from and how were they discovered as a successful biological model for research As Zebrafish are used by more and more facilities around the world an understanding of what they have to offer as a research model is required Scientific Programme 43

Platform Programme and Workshop Sessions WEDNESDAY 22nd MARCH Basic husbandry housing and water quality Zebrafish require a stable environment with specific ranges of water quality as well as multiple feeds per day with different types of diet So what exactly is involved with the day to day husbandry As technology improves so do aquatic housing systems How were the first systems designed and what improvements have been made over the years to attain the highest level of welfare for aquatic species Ill health and disease prevention healthy fish lead to healthy science so it is imperative that everything that can be done to provide the best housing environment is implemented It is also highly important to understand the early warning signs of stressed fish and what can be done to minimise the stressing factors There are many common Zebrafish diseases that can impact on colonies within a facility so what signs present themselves and how are the fish affected Nutrition choosing the right diet and feeding regime can play a large part in the health and breeding potential of Zebrafish so it is important to understand what is available on the market and which types of diet provide the best nutritional value 10 45 W7 Using the science of human behaviour change to improve the welfare of research animals Suzanne Rogers BSc Hons ChBC International Consultant for Animal Welfare and Human Behaviour Human Behaviour Change for Animal Welfare Community Resource It can sometimes be challenging to engage all staff in the most refined procedures and handling techniques for research animals This two hour workshop will explore how understanding the science of human behaviour change can help you increase your influence and improve the take up of good practices The workshop will be interactive and involve group exercises reflection as individuals and material presented by the facilitator It will include practical sessions to explore ways of applying the concepts to the research animal setting Topics include l the process of change e g the Theory Of Change planning tool l t he psychology of change exploring motivation barriers habits routines beliefs attitude and group psychology l the environment for change including organisational culture of care l t he ownership of change e g using participatory methods of education and peer to peer interactions to facilitate change 10 45 W8 IVC environmental health monitoring 3Rs and colony management Patrick Hardy DVM DipECLAM Exec MBA1 and Pete Willan DMS FInstMgt MIAT RAnTech2 1 Director of Veterinary and Professional Services Allentown Inc 165 Route 526 Allentown New Jersey 08501 USA 2 Product Specialist UK and Europe Veterinary and Professional Services Allentown Europe PO Box 3056 Reading Berkshire RG1 9UY Combined advances and innovations in qPCR technology and in IVC exhaust sampling capture systems represent a major opportunity to improve very significantly the management of IVC environmental health monitoring HM at different levels l i mproving operational practicalities of sampling for HM l i mplementing the 3Rs through a significant reduction of animal sentinel use l i ncreasing the sensitivity and reliability of HM versus sentinel animals and soiled bedding transfer 44 Scientific Programme

Platform Programme and Workshop Sessions WEDNESDAY 22nd MARCH Comparative studies and field testing have allowed assessing the value of IVC environmental HM versus traditional sentinel based methods to be assessed The workshop will address the following topics lk ey objectives and principles of a HM programme design lp rinciples of PCR techniques versus other diagnostic assays including interpretation and limitations of results l l imitations of HM based on sentinel animals exposed to soiled bedding lp erformance of environmental health monitoring in IVC systems results from pilot and field multi centric studies l c onduct and practicalities of various environmental sampling methods for PCR at cage and rack level versus animal based sampling methods l c ross contamination control during sampling l c ontribution of environmental HM to the quality reliability of a HM programme including the implementation of FELASA recommendations to 3Rs implementation and also the cost practicalities of HM operational management 12 45 LUNCH served in the Trade Exhibition Hall Foyer 13 00 MEET THE POSTER AUTHORS Trade Exhibition Hall Foyer 13 15 WORKSHOP SESSIONS Further details appear on page 67 onwards 13 15 W2 Working with minipigs all you ever wanted to know Adrian Zeltner LabTech FELASA A and B Customer Support and Veterinary Services Ellegaard G ttingen Minipigs A S Soroe Landevej 302 4261 Dalmose Denmark For any type of work with animals a profound understanding of the species involved is paramount Conducting studies with minipigs is no exception Proper handling and training of the minipig will greatly contribute to the success of the study and animals welfare In this workshop we will explore what it means to work with minipigs and any other practical aspects that may arise from the participants Topics include lb iology of the minipig lb ehaviour of minipigs lw elfare needs lh ousing l acclimatisation l handling l dosing l training 13 15 W4 Practical aseptic technique basic Olga Woolmer DVM MRCVS1 and Alexandros Zervas DVM MRCVS2 1 2 Named Veterinary Surgeon Royal Veterinary College Royal College Street London NW1 0TU Come and join us at either or both of our interactive sessions The basic workshop will introduce Animal Technologists to aseptic technique for surgery We will help you to understand the reasons behind the use of aseptic technique in surgery Scientific Programme 45

Platform Programme and Workshop Sessions WEDNESDAY 22nd MARCH whether for long or short term procedures from mice to rabbits to camelids Using an interactive style you will learn the techniques that make up best practice in surgical preparation and practice There is also the chance to see many of the options that are available to you without having to spend a fortune or take a long time preparing your surgical area We also welcome your questions suggestions and would like to share your experiences in order to help you optimise your procedures once you re back in your home Institute Topics include basic l pre operative care l setting up a surgical area l preparing the animal l preparation for surgery l post operative care 13 15 W5 Severity classification and reporting Kathy Ryder MB BS BSc MRCP DPhil Inspector Animals in Science Regulation Unit Home Office 2 Marsham Street London SW1P 3DF To examine the process of assessing and reporting severity and examining the challenges of achieving consensus ASPA requires the classification of procedures according to severity during the application for a project licence There is also a requirement to report the actual severity experienced by each animal used in a procedure Both these processes provide opportunity to refine the adverse effects of procedures Consistency of assignment of severity categories across the UK is required so that information provided is accurate and usable Topics include l i dentifying the components within the procedures which may cause pain suffering distress or lasting harm ld efining the adverse effects and mitigation l i dentifying appropriate end points la ssigning prospective severity classification la udience response session Turning Point to consider examples of actual severity assessment 13 15 W10 Nice to meet you so what do you do for a living Bella Williams BSc Hons DPhil MIKE1 and John Meredith BA2 1 Head of Engagement Understanding Animal Research UAR Hodgkin Huxley House 30 Farringdon Lane London EC1R 3AW 2 Head of Education and Outreach Understanding Animal Research UAR Hodgkin Huxley House 30 Farringdon Lane London EC1R 3AW Many people who work in life sciences worry about this question but for Animal Technologists it can be particularly difficult The aim of this workshop is to help attendees feel equipped and empowered to have conversations about their work We will explore how we handle this question and give the opportunity to discuss our responses In this era of greater openness can we talk about our work more When is it the right thing to do and when should we avoid the subject Topics include l speaking out what are the risks what are the benefits l dealing with challenge keep talking or walk away l preparing for tough questions l openness in research 46 Scientific Programme

Platform Programme and Workshop Sessions WEDNESDAY 22nd MARCH 15 00 TEA COFFEE served in the Trade Exhibition Hall Foyer 15 30 WORKSHOP SESSIONS Further details appear on page 67 onwards 15 30 W1 How to be an AWERB champion Penny Hawkins BSc PhD Deputy Head Research Animals Department RSPCA Wilberforce Way Southwater West Sussex RH13 9RS Animal Technologists already act as valuable members of the Animal Welfare and Ethical Review Body AWERB and this workshop aims to encourage even more active participation It is suitable for those who are already AWERB members and others who are considering becoming involved See Topics on page 43 15 30 W4 Practical aseptic technique advanced Olga Woolmer DVM MRCVS 1 and Alexandros Zervas DVM MRCVS 2 1 2 Named Veterinary Surgeon Royal Veterinary College Royal College Street London NW1 0TU Come and join us at either or both of our interactive sessions For the more experienced audience the advanced workshop will cover the more intricate aspects of sole surgery as opposed to working in a surgical team We also welcome your questions suggestions and would like to share your experiences in order to help you optimise your procedures once you re back in your home institute Topics include advanced l s terility of delicate instruments l l ong term anaesthesia l a nalgesia 15 30 W6 Preparing to present for the first time Diana Baumann BSc Hons RLATG CMAR Head of Reptile and Aquatics Stowers Institute for Medical Research 100E 50th Street Kansas City Missouri 64110 USA This workshop will be tailored towards those who would like to present at a meeting but never have Barriers to giving a presentation include fear of public speaking and not knowing what to talk about or how to talk about it Topics covered in this interactive session will include choosing a topic the preparation process knowing your audience explaining tough concepts and giving the talk itself How adults learn and exercise to overcome nervousness will also be incorporated Attendees will ideally come with an initial idea of a topic on which they would like to create a presentation and hopefully this session will provide the framework to allow them to go out and speak with success 15 30 W9 Playtime for rats Kathryn Owen BSc Hons MRes PhD National Centre for the 3Rs NC3Rs Gibbs Building 215 Euston Road London NW1 2BE In 2017 the NC3Rs has decided to spotlight the welfare needs of the laboratory rat Together with AstraZeneca our workshop aims to explore approaches to providing laboratory rats with a complex environment and increased opportunity to exercise We will focus on how Animal Technologists can consider practical implementation within their institution Outputs from the meeting will include a short paper highlighting opportunities and barriers to adoption Scientific Programme 47

Platform Programme THURSDAY 23rd MARCH VENUE caernarfon suite Chair V icky Robinson CBE BSc PhD Vice President Institute of Animal Technology and Chief Executive NC3Rs PAPER SUMMARIES 09 00 The Home Office Update ASRU latest news Sue Houlton MA BVSc DVR DVC MRCVS1 and Will Reynolds BSc Hons MPhil2 1 Chief Inspector Animals in Science Regulation Unit Home Office Marsham Street London SW1P 4DF 2 Head of Policy Planning Animals in Science Regulation Unit Home Office Marsham Street London SW1P 4DF Representatives from the Home Office will deliver an update on all that is current within the Animals in Science Regulation Unit ASRU FIRST TIME PRESENTERS sponsored by Marshall BioResources 09 30 Light intensity and its impact on survival rates of pigmentless Zebrafish Danio rerio Paul Barwood BSc Hons Aquaculture and Fisheries Management University College London Division of Biosciences Gower Street London WC1E 6BT The Zebrafish Danio rerio is a species with increasing importance across many scientific disciplines however much about their husbandry requirements is still poorly understood misunderstood or unknown Many research disciplines utilise strains of Zebrafish with lesser levels of pigmentation than a normal Zebrafish but the husbandry and larval rearing of such fish is still poorly understood Through database analysis at UCL it has become apparent that larval pigmentless strains of Zebrafish have a lower survival rate than those with pigment We believe one factor influencing this is the lighting intensity as it is known that albino rodents have a lower light aversion threshold than their pigmented counterparts The accepted lighting standard for Zebrafish is to replicate a day and night cycle of 14 hours daylight and 10 hours of night darkness but light intensity recommendations are vague or non existent We thought that the ambient lighting level in the room necessary for humans to perform visual tasks would have an adverse effect on the survival rates of larval forms of some pigmentless strains and that this could be ameliorated by housing fish in a position further away from the light source Our studies have shown this not to be the case To test this hypothesis further we used a pigmentless fish TraNac and pigmented Wild Type Zebrafish and analysed their performance when housed in transparent opaque and coloured tanks therefore exposing the fish to different light levels whilst being housed on a normal racking system 09 50 Refinement of tumour passage by optimisation of the tissue disaggregation protocol Melanie Galvin MSc Biomedical Science Cancer Research UK Manchester Institute Wilmslow Road Manchester M20 4BX Surgical implantation of tumour pieces is used regularly in the passage of tumour models This involves an invasive surgical procedure carried out under anaesthesia ensuring the mice have adequate pain relief and peri operative care The procedure also requires multiple tumour bearing donor mice to generate sufficient tissue 48 Scientific Programme

Platform Programme THURSDAY 23rd MARCH for surgical implantation particularly for large scale efficacy studies Using the gentle MACS Disassociation Kit Miltenyi Biotech we sought to refine our tumour passage methods and subsequently reduce the number of mice required for studies Tumours were disaggregated mouse red blood cells eliminated and any dead residual mouse cells removed The remaining tumour cells were mixed with matrigel and implanted subcutaneously in the hind flank of mice Results have shown that tumours are able to grow successfully via this method and cell viability has been maintained growth assay Due to the number of cells generated using this protocol we are able to implant more mice per tumour thus reducing the number of donor mice required Moreover the implantation procedure is less invasive and a milder severity performing a subcutaneous injection rather than a surgical implant under general anaesthesia Not only does this process improve animal welfare from a 3Rs perspective it also improves other aspects of the experiment by reducing intertumour heterogeneity thus improving the science 10 10 Refinements in rat dual cannulation surgery by using the vascular access button offering the advantage of group housing Samantha Izzard MIAT GlaxoSmithKline Gunnelswood Road Stevenage Hertfordshire SG2 0HT The current procedure for dual cannulation surgery involves Wistar Han male rats being individually housed and placed in a vascular access harness The rats take up to seven days to recover their pre operative weight and may experience grazing from the bands This project evaluated the use of the vascular access button and housing of the rats in pairs post operatively If successful it could mean that the rats would be harness free regain pre operative weight within a couple of days and as social animals be pair housed We initially set a meeting up with the NVS and project licence holder to discuss the new model development and how it could improve the welfare of the rats and study outcomes We developed the technique using a rat cadaver and once we were confident with the placement of the button we carried out a live trial using aseptic techniques in recovery surgery For the assessment we monitored rat weight healing and behaviour towards cage mate All animal studies were ethically reviewed and carried out in accordance with Animals Scientific Procedures Act 1986 and the GSK Policy on the Care Welfare and Treatment of Animals This presentation will discuss the aseptic technique used method and results as well as the future plans for the rat dual cannulation surgery at GSK 10 30 COFFEE TEA served in the Trade Exhibition Hall Foyer Chair V icky Robinson CBE BSc PhD Vice President Institute of Animal Technology and Chief Executive NC3Rs FIRST TIME PRESENTERS sponsored by Marshall BioResources 11 15 Advances in transgenic technology Elizabeth Hurd PhD University of Edinburgh Central Bioresearch Services Institute of Genetics and Molecular Medicine Western General Hospital Crewe Road Edinburgh Midlothian EH44 2XU Transgenic animal models have had a huge impact on scientific research and have led to a greater understanding of complex biological processes In addition they have also significantly contributed to the development of new treatments Scientific Programme 49

Platform Programme THURSDAY 23rd MARCH of both human and animal diseases However production of specific transgenic animal models has historically taken a long time usually years using conventional methods of gene targeting Since 2013 there has been a revolution in the field of transgenic production that has significantly reduced the time it takes to generate novel animal lines with specific mutations These new gene editing tools called CRISPR Cas9 are now being routinely used by transgenic facilities around the world with great success They are also being used in clinical trials to directly target human disease Here I describe this new gene editing technology and highlight the potential advantages in relation to the NC3Rs when generating novel lines for scientific research 11 35 Working with poultry in avian viral disease research spreading our wings Megan Cooper BSc Animal Science Behaviour and Welfare The Pirbright Institute Ash Road Woking Surrey GU24 0NF In 2015 of the 4 14 million procedures performed on animals in research only 3 4 were performed on birds Annual Statistics of Scientific Procedures on Living Animals Great Britain 2015 Home Office UK Due to the relatively low numbers of poultry used in UK research studies there is a historical paucity of readily available information and scrutiny on the welfare and enrichment of birds kept for scientific research especially those involving infectious diseases The Pirbright Institute TPI is home to an extensive avian viral disease programme and has helped develop several lines of genetically defined chickens with differential resistance to various disease agents These birds are used both in embryonic form and post hatch chicks at various stages of development by our scientists An avian support technician s job is to ensure the chickens we use here at TPI are cared for with compassion and to the highest standard of welfare possible The purpose of this presentation is to give an insight into the aims operations and difficulties of a poultry experimental facility and to shed new light on this often overlooked species The topics covered will include husbandry enrichment and regulated procedures describing some of the ways TPI has tailored its housing and methods of husbandry to refine poultry welfare I will explain the main aspects of working with poultry and highlight some of the reasons why a job hatching and raising chickens for use in animal research can be extremely rewarding Focus on improving welfare reducing stress and aiding recovery of surgical 11 55 procedures Emma Vacca University of Cambridge Innes Building Madingley Road Cambridgeshire CB3 0ES All surgery can be stressful to some degree This presentation focusses on and identifies causes of stress from husbandry handling and enrichment choices in rats Literature is replete with studies on stressors to the laboratory rat therefore a review was undertaken which focused specifically on refinements for rats used as a surgical model in spinal cord and brain lesioning surgeries The aim of this review was to collate best practice describe our own practical refinements that we have found beneficial and to suggest what current best practice should be Our intention is to help reduce suffering and improve welfare without compromising the scientific objectives by refining pre and post surgical procedures in order to cause minimal stress to the rats 50 Scientific Programme

Platform Programme THURSDAY 23rd MARCH 12 15 ANDREW BLAKE TRIBUTE AWARD sponsored by Presentation of the 2017 Winning Paper The Association of the British Pharmaceutical Industry Time for change practicalities of implementing non aversive methods for handling mice John Waters BSc Hons MIAT NACWO Mammalian Behaviour and Evolution MBE Group Institute of Integrative Biology University of Liverpool Leahurst Campus Neston Cheshire CH64 7TE Recent studies have shown that the method choice for handling laboratory mice is important to animal welfare In 2015 60 of all animals used in Home Office procedures were laboratory mice Given the large number of mice within global facilities mouse welfare should be given high priority Improved handling not only leads to more consistent scientific data it can also lead to improved animal welfare Historically mice have been picked up by their tail a method that has been passed down to generations of Technicians Animal Technologists and is widely accepted as a method of handling Hurst and West 2010 showed that picking up mice by their tail induces aversion and high anxiety By contrast using alternatives such as a tunnel or cupped on the open hand leads to voluntary approach to the handler low anxiety and animals that more readily accept some physical restraint Hurst and West s findings were consistent across strains and sex of laboratory mice handlers with differing levels of experience and different light periods light dark From a welfare perspective the response from the mice on a daily basis is a positive step in the right direction The evidence presented by Hurst and West indicates that a change to the standard method for picking up mice would provide improved welfare for millions of mice worldwide However this will only happen if the non aversive methods are taken up by facilities To be successful the practicalities of these methods need to be demonstrated and appropriate instruction provided for technical staff and researchers to aid implementation of the methods First I gained information from talking to Technicians Animal Technologists conducted a survey of their responses concerning key issues and established practical details of implementation in our own facility I then played a major part in designing and constructing a video based tutorial with accompanying commentary to demonstrate the handling methods and their use in common laboratory situations from a practical Technologists viewpoint This includes ways to avoid common problems in implementation to reduce stress in both animals and the Technicians carrying out the handling Although my main focus was practical implementation from an Animal Technologist s perspective as this will have the greatest impact on implementation the tutorial provides important training material for technical staff and researchers alike 12 45 LUNCH served in the Trade Exhibition Hall Foyer Scientific Programme 51

Platform Programme THURSDAY 23rd MARCH Chair R obert Weichbrod MBA PhD Vice President Institute Animal Technology ail Thompson RLATG Chair G Vice President Institute Animal Technology PAPER SUMMARIES 14 00 Using the science of human behaviour change to improve the welfare of research animals Suzanne Rogers BSc Hons International Consultant for Animal Welfare and Human Behaviour Human Behaviour Change for Animal Welfare Community Resource The root cause of much compromised animal welfare is what humans do or do not do For research animals it can sometimes be challenging to engage all staff in the most refined procedures and handling techniques This presentation will explore how understanding the science of human behaviour change can help you increase your influence and improve the take up of good practices We consider human behaviour change in four pillars the process of change e g the Theory Of Change planning tool the psychology of change exploring motivation barriers habits routines beliefs attitude and group psychology the environment for change including organisational culture and ownership of change e g using participatory methods of education and peer interactions to facilitate change This talk will summarise the emerging interest in human behaviour change to improve animal welfare and then provide examples of how some of the key principles of human behaviour change can be applied to the research animal setting An example of the importance of teaching in an interactive way and providing ongoing support will be described The author ran three educational workshops in three different ways and compared resulting behaviour change after each one The most effective approach was an interactive workshop with facilitated peer support afterwards I will discuss how this approach can be applied in a laboratory setting to encourage good practice Further applying the science of why humans do and do not do behaviours that affect animals will enable us to be more effective at improving the welfare of animals used in research 14 30 You have the best ideas Norman Mortell MIAT BA Hons Agenda Life Sciences PO Box 24 Hull East Riding of Yorkshire HU12 8YJ New ideas improvements and innovations are all around us and they are also lurking within our own organisations we just need a way to enable them to surface and to nurture them We hope that this presentation will inspire attendees to look inwards to their own staff who often have the best ideas This real life case study describes how a management challenge can be applied to any organisation and to all levels of staff Empowering individuals to develop something new can have many positive impacts for the organisation but also for the development of the individual This case study will describe the framework used and the real tangible and long term benefits that were developed 52 Scientific Programme

Platform Programme THURSDAY 23rd MARCH 15 00 POSTER PRESENTATIONS sponsored by LBS Four informal ten minute oral presentations on a variety of topics will be made by the authors of selected posters This is a particularly popular session as questions from the audience usually lead to lively discussions Ultrasonic vocalisation as a measure of positive welfare in rats Tim Jones DSTL Porton Down Creatively meeting the standards taking rabbit housing to the next level Katherine Marshall Oregon Health and Science University Advances in welfare and scientific outcomes of the bile duct cannulated rat model utilised in absorption distribution metabolism and excretion ADME studies Hans van Wijk Covance Laboratories A method for repeated dosing of juvenile mice via oral gavage Peter Paccagnini Sequani Ltd Further details appear on page 56 onwards 15 45 MEET THE POSTER AUTHORS Trade Exhibition Hall Foyer 15 45 TEA COFFEE served in the Trade Exhibition Hall Foyer Scientific Programme 53

Platform Programme THURSDAY 23rd MARCH Chair Ken Applebee OBE FIAT FRSB Chair Institute of Animal Technology 16 15 KEVIN DOLAN MEMORIAL LECTURE ANIMALS THAT ARE OUT OF THIS WORLD Julie Keeble PhD Institute of Pharmaceutical Science King s College London Franklin Wilkins Building 150 Stamford Street London SW1 9NH 17 00 Presentation of Awards First Time Presenter 2017 sponsored by Marshall BioResources Best Poster 2017 sponsored by LBS Journal Article Prize 2016 Animal Technology and Welfare Marjorie Sandiford Whittingham Memorial Prize Tania Boden and Penny Hawkins Winners Andrew Blake Tribute Award 2017 sponsored by The Association of the British Pharmaceutical Industry John Waters Winner AAALAC International USA Fellowship Award 2017 Katherine Marshall Winner 17 15 Close of Congress 2017 Ken Applebee OBE FIAT FRSB Chair Institute of Animal Technology 54 Scientific Programme

KEVIN DOLAN MEMORIAL LECTURE Animals that are out of this world Julie Keeble PhD Institute of Pharmaceutical Science King s College London FranklinWilkins Building 150 Stamford Street London SW1 9NH Animals have been orbiting the earth since the 1950s when Laika a dog was launched aboard the Soviet Sputnik 2 spacecraft Laika died in orbit as was the plan because the technology did not exist to bring the dog back to earth Several animals had reached space before that but had not made it into orbit the first of which were fruits flies Drosophila in 1947 Animals play an enormously important role in understanding how microgravity affects the physiology of living organisms including their cardiovascular system respiratory system and behaviour amongst other things Most recently astronauts and cosmonauts have been studying their behaviour aboard the International Space Station ISS Animals that have been studied in space include wasps beetles tortoises flies fleas worms fish spiders rabbits bees ants frogs mice crickets rats newts snails urchins moths brine shrimp jellyfish Guinea pigs butterflies scorpions and cockroaches Recently a new dedicated rodent facility was launched to the ISS and has been housing mice for research purposes This presentation will give some background to the use of animals in space and will give an overview of current challenges to carrying out research on animals aboard the International Space Station with respect to welfare and practicalities from launch to beyond Julie Keeble Dr Julie Keeble is the Named Training and Competency Officer NTCO and a lecturer in Pharmacology at King s College London She is also the Chief Scientist for the International Space School Educational Trust ISSET Julie has 19 years of experience of in vivo Pharmacology holding two Home Office project licences including one for educational purposes and has been the NTCO at King s since December 2014 Since July 2012 Julie has been working on behalf of ISSET and school pupils around the globe to send experiments to the International Space Station ISS In total Julie has sent 7 experiments with 10 more in the pipeline for launch involving interactions with various astronauts including Major Tim Peake During the course of her work in Space Julie has developed expertise in how scientific experiments are carried out on the ISS including the rodent facility Scientific Programme 55

Poster Presentations THURSDAY 23rd MARCH Caernarfon Suite convention level C1 15 00 15 45 Ten minutes is allocated to each participant with additional time allowed to address questions that may arise Each abstract appears on the following pages in the running order as below Ultrasonic vocalisation as a measure of positive welfare in rats Tim Jones Creatively meeting the standards taking rabbit housing to the next level Katherine Marshall Advances in welfare and scientific outcomes of the bile duct cannulated rat model utilised in absorption distribution metabolism and excretion ADME studies Hans van Wijk A method for repeated dosing of juvenile mice via oral gavage Peter Paccagnini 56 Scientific Programme

Poster Presentations POSTERS Chair R obert Weichbrod MBA PhD Vice President Institute Animal Technology Chair G ail Thompson RLATG Vice President Institute Animal Technology Ultrasonic vocalisation as a measure of positive welfare in rats Tim Jones Defence Science and Technology Laboratory DSTL Building 04 C49 Porton Down Salisbury Wiltshire SP4 0JQ Rats are a widely used laboratory species in research Studies of animal welfare in laboratory animals have historically relied on the measurement of negative indicators rather than the assessment of positive indicators of welfare Practical methods of welfare assessment are required to allow refinement of housing and experimental protocols Ultrasonic Vocalisation USV can be used as a measure of positive and negative emotional state This poster compares the production of USV in the frequency range associated with positive emotional state in rats 50 kHz within two different cage types and considers the utility of USV recording as a welfare indicator assessing both its practicality and effectiveness Creatively meeting the standards taking rabbit housing to the next level Katherine Marshall Oregon Health and Science University 505 NW 185th Avenue Beaverton Oregon 97006 USA The 8th Edition of the Guide for the Care and Use of Laboratory Animals clarified its language regarding housing social species specifying that Single housing of social species should be the exception This is a challenge for many institutions in the USA as often budgets for new housing need to be planned far in advance Furthermore while rabbits are social by nature not all rabbits engage in a positive and mutually beneficial manner with conspecifics resulting in the need to be creative when ensuring their social needs are being met Our facility has implemented multiple solutions to this challenge through the use of technology secure play space and modifications to current equipment These solutions have allowed us to meet the requirements set forth in the new Guide in a resource effective and environmentally friendly manner while minimising disruption to the rabbits Scientific Programme 57

Poster Presentations Advances in welfare and scientific outcomes of the bile duct cannulated rat model utilised in absorption distribution metabolism and excretion ADME studies Hans van Wijk Covance Laboratories Otley Road Harrogate HG3 1PY Rats are typically the rodent species of choice for investigating the Absorption Distribution Metabolism and Excretion ADME of new chemical entities Because rats lack a gall bladder they are an ideal model for investigating excretion and metabolism in bile To facilitate bile collection catheters are placed in the bile duct of the liver in order to collect bile and into the duodenum where artificial bile salts are infused Both catheters are exteriorised via a tail cuff and require the animal to be tethered and singly housed for the duration of both the recovery and experimental period which is typically up to ten days A modified tail cuff has been developed using a pinport adapter that permits the animal s own bile to be re routed back into the duodenum during the recovery period This modification means that animals do not need to be tethered or singly housed during this time A method for repeated dosing of juvenile mice via oral gavage Peter Paccagnini Sequani Ltd Bromyard Road Ledbury Herefordshire HR8 1LH Whilst the rat is the most common rodent used in juvenile toxicity studies mice are sometimes a more suitable model Challenges in dosing mice via oral gavage are considerable due to their smaller size and being less co operative than rats The objective of this study was to develop an effective method for repeat dosing mice from Post Natal Day PND 14 via oral gavage Animals were dosed either at PND 21 or PND 14 for five days using two types of dosing equipment 58 Scientific Programme

Poster Displays The emotional impact on Animal Technologists working with animals Tracy Benford Public Health England Porton Down Salisbury Wiltshire SP4 0JG This poster will look at the emotional impact on Animal Technologists working with animals how it is managed ways to make things better for staff and improving understanding of the subject The life of birdie hand rearing for comparative cognition studies Sam Melvin University of Cambridge High Street Madingley Cambridge CB23 8AA Various corvid species are used for comparative cognition research at Cambridge University Animal Technologists responsibilities include general husbandry breeding and assisting with research where needed As Western scrub jays can no longer be imported from California breeding and hand rearing at the animal behaviour site in Madingley was attempted by the Animal Technologists This poster will include information on raising a Western Californian scrub jay the problems faced and possible solutions for the future Tail cuff infused nude mice comparison of continuous versus intermittent tethering with the pinport in tail cuff system including histopathological parameters Hans van Wijk Covance Laboratories Otley Road Harrogate HG3 1PY The nude mouse has been used to generate human tumour xenografts for testing antitumour efficacy of new anti cancer agents Intravenous administration of compounds can be given as a slow bolus injection tail vein or by an implanted femoral catheter with tail cuff exteriorisation In continuously tethered mice up to now the tether limits studies to 28 days since the weight of the tether together with a wire passed through the tail to secure the cuff results in severe tissue damage The local lesions can be reduced in intermittently connected mice Histaminergic reactions lower susceptibility of mice versus rats and modification by infusion rate Hans van Wijk Covance Laboratories Otley Road Harrogate HG3 1PY Non immunologically triggered hypersensitivity is well known for radiocontrast agents antibiotics anaesthetics analgesics and some peptides proteins and has a clear impact on their efficacy safety testing As more parenteral biologics e g therapeutic antibodies are being developed these histaminergic reactions gain importance The effect of infusion rate on probability and severity of histamine release in several species has been previously observed Preliminary results from a dose range finder study with Trasylol a known inducer of hypersensitivity suggested that a the rat is more prone to the induction of histamine release than the mouse and b infusion rate over six hours clearly reduced Scientific Programme 59

Poster Displays histamine release in the mouse and rat To substantiate this finding five rats and five mice each surgically implanted with an indwelling femoral vein catheter were bolus injected or infused over six hours The results confirm histamine release and thereby induced clinical symptoms can be modified by the infusion rate in both rats and mice In the mouse the intrinsic stores appear to be lower than in the rat Furthermore the feasibility in infusing freely moving mice via indwelling vein catheter was demonstrated thereby avoiding local vein damage and dosing variability as seen with the traditional tail vein injection Contaminating DNA can give false positives in sentinel free health monitoring by PCR on exhaust air dust samples Andrew Dickinson Surrey Diagnostics Ltd PO Box 156 Cranleigh Surrey GU6 8ZU Following the introduction of sentinel free animal health monitoring by PCR on the dust collected on filters in the exhaust plenums of IVC Individually Ventilated Cage racks we present a case where exhaust filters gave positives by PCR for agents which had not previously been found by microbiological culture in that colony on multiple live animal samples across the life span of the IVC exhaust filter Our own experience along with other accounts of false positives from other users possibly due to the presence of contaminating DNA of an environmental source such as diet and bedding led us to the hypothesis that the sentinel free PCR method could be prone to false positives due to the presence of contaminant DNA from infectious agents of mice Using real time PCR for detection of the mouse cox gene we found that mouse DNA was indeed present in clean diet and bedding at a low level indicating that the DNA of infectious agents of mice could also be present This therefore could be a mitigating factor in the reliability of health monitoring by PCR on plenum filters alone These false positives on plenum filters cost the research facility a considerable amount of time and money through subsequent extra testing to track down the source of the problem The curious tale of Axolotl enrichment Emma Billingham University of Nottingham Queens Medical Centre Nottingham NG7 2UH Axolotls can be used in scientific research to provide fertilised embryos for investigations into the genetic pathways controlling stem cell development Breeding animals are housed for several years and environmental enrichment is required to improve welfare by providing axolotls greater choice within their aquatic environment Therefore there is a need to investigate the addition of enrichment Although research has proven that enrichment creates positive behaviours for rodents and other species it is not confirmed for axolotls Research has been attained for Zebrafish enrichment but no conclusive results exist for axolotls The current study has examined the effect of different types of enrichment including rocks plants plastic shelters compact discs on a range of behavioural measures The objective was to understand if enrichment is engaged with and also to observe behaviours which are exhibited in the environment by axolotls 60 Scientific Programme

Poster Displays The introduction of a cable tie swing and its impact on animal welfare Laura Dean Cancer Research UK Manchester Institute University of Manchester Wilmslow Road Withington Manchester M20 4BX Common enrichment for mice is usually restricted to the floor and easily damaged leading to frequent replacement We have been studying the behaviour of NOD Cg PrkdcIl2rg Szj NSG mice towards a swing made from plastic cable ties This enhances the 3 dimensional space which is an advantage for animals that naturally like to climb The cable ties are cost effective easy to assemble and autoclavable making them safe for re use Refining the palpation technique to improve monitoring in the transgenic mouse Gemma Forrest Cancer Research UK Manchester Institute University of Manchester Wilmslow Road Withington Manchester M20 4BX A number of new strains of mice arrived at the Manchester Institute They were expected to develop ovarian tumours potentially occurring from six weeks of age onwards We have facilities to ultrasound animals to investigate tumour development however due to the quantity of animals involved and the speed these tumours can develop this was not possible This also required each animal to be placed under anaesthesia every week for a prolonged period of time Using NVS guidance and modifying our palpation technique we have developed an accurate method of detecting and monitoring internal ovarian tumours This reduces the number of procedures refines the way we detect internal tumours and defines an end point before animals become visibly sick This poster will show how we refined our palpation technique using advice from the NVS and our own observations to develop a healthy time point at which to remove animals from the study Rodent cage compliance both challenging and beneficial Christian White Envigo Shaw s Farm Station Road Blackthorn Bicester OX25 1TP Compliance with section 2 of the ASPA Code of Practice became mandatory on 1st January 2017 Operating a full barrier and maintaining large rodent breeding and supply programmes while meeting the required changes in cage sizes occupancy presented challenges but also created opportunities to further develop our animal welfare This poster will outline the project discussing the processes put in place in order to achieve compliance maintain facility integrity while minimising the impact on our operations We will discuss the benefits not only to animal welfare but also for the staff caring for our animals as a result of this project Scientific Programme 61

Poster Displays Rabbit pens or cages does the housing influence enrichment preferences Samantha Levent Envigo Hillcrest Dodgeford Lane Belton Loughborough LE12 9TE Since the antibody production facility at Envigo RMS opened in 2015 we have been offering our rabbits a combination of disposable and non disposable enrichment We had perceived that there were differences between the preference of rabbits housed in pens when compared to rabbits housed in cages but had no data to support this This study was designed to provide evidence of preference which has enabled us to tailor an enrichment rota specific for animals housed in different environments SPONSORSHIP The Congress Committee wish to thank all the companies that have supported Congress by Exhibiting and or Advertising in this Handbook The following companies and organisations are especially thanked for their further sponsorship Andersons Bedding Products Aston Pharma AW Anaesthesia Services Institute of Animal Technology MBK Installations S3 Science Recruitment Surrey Diagnostics Venture Forward Notepad DBM Scotland Ice Breaker Envigo Mug Institute of Animal Technology Delegate bags and Wine Reception for official opening of Trade Exhibition Institute of Animal Technology and The Association of the British Pharmaceutical Industry Andrew Blake Tribute Award IPS Product Supplies Ltd Badge LBS Best Poster Award Marshall BioResources First Time Presenter Award Tecniplast Quiz Night Transnetyx Pens 62 Scientific Programme

Poster Displays Optimising feeding regimes and stocking densities in Zebrafish Danio rerio David Mortell University of Manchester Stopford Building Oxford Road Manchester M13 9PT We utilised fish from the University of Manchester s BSF wildtype Zebrafish stock on four different feeding regimes with the aim of finding the most beneficial Each feeding regime started off with two tanks on each We split down the number of fish in one of the two tanks on each regime at one month old and left one tank to be split down at two months old to compare juvenile development We recorded the difference in size between the smallest and largest fish in each tank and noted any obvious development abnormalities We recorded the fry survival rates in each tank from day five to two months old The aim was to find the most appropriate feeding regime to improve fry survival rates and if splitting the fish down into more appropriate stocking densities at one month old would prove to be beneficial to developing fish The IAT App April Shipton Oxford University Biomedical Services The Old Observatory South Parks Road Oxford OX1 3RQ The new IAT Congress event App provides an interactive experience for delegates It allows personalised schedules to be created for workshop paper and poster sessions Interactive maps can be accessed directly from each session and from exhibiting company profiles so you never get lost Interact with other delegates using the social wall and activity feed Get involved in Congress 2017 and earn points for completing simple tasks using the App There are prizes available 3Rs improvements in the BEXSERO Meningitis B vaccine potency test Lisa Johnson Cancer Research UK CRUK Blanche Lane South Mimms Potters Bar Hertfordshire EN6 3LD This in vivo test is performed in the Biological Services Division BSD and uses CD1 mice and involves two intra peritoneal injections of sample and reference vaccines and blood sampling after four weeks These vaccines contain serial dilutes with Aluminium Hydroxide adjuvant ALOH Adverse effects were commonly observed in the mice post injection This is more prevalent in the higher dose groups and includes lethargy pilo erection orbital tightening abnormal gait and abdominal contractions which are considered to be pain related Some animals from the higher dose groups were found upon post mortem examination to have small internal lesions It is thought the adverse effects and lesions are caused by the ALOH adjuvant This poster details the 3Rs improvements made to the test including a reduction in the number of mice required for each test and refinements to improve the animals overall experience Scientific Programme 63

Poster Displays Rise of the rotifers Brine shrimp who needs them Dimitra Mantzorou Zebrafish Facilities King s College London Newcomen Street London SE1 1UL Zebrafish facilities worldwide face growing pressure to identify new live diets while the available Brine shrimp cysts stocks are becoming increasingly expensive and of a less reliable quality At King s College London in keeping with the principles of the 3Rs we have refined our previous live diet protocol and established a new more efficient low salinity rotifer protocol with enough turnover to replace all Brine shrimp feeding practices in our two facilities holding approximately 40 000 Zebrafish By replacing the conventional Brine shrimp feeding regime with this latest rotifer protocol we have been able to maintain a reliable continuous source of live diet in a single convenient process for all Zebrafish life stages Other advantages include control over the nutritional value of our live diet drastically reduced staff time and supply costs The importance of high quality health and phenotype information prior to importing new genetically altered GA lines Annabelle Christi Charles River UK Manston Road Margate Kent CT9 4LT In 2001 the Animal Procedures Committee APC and other organisations including the Joint Working Group on Refinement published reports recommending that information should be collated for all Genetically Altered GA mice regarding their creation breeding husbandry and care Charles River UK Ltd is licensed to provide housing breeding and scientific procedure services for GA mice and rats to various academic and commercial establishments We have created a Genetically Altered Model Information Form GAMIF based on the mouse passport recommended by RSPCA GA Passport Working Group GAPWG and our Corporate Animal Welfare Group to collect all required information in a standardised format prior to delivery and or creation of new GA strains This poster shows how we use the GAMIF to collect and communicate the information related to phenotype housing husbandry and the colony s health status at origin both internally to Named Persons and Animal Technologists and externally to our customers Introducing best practice for breeding rabbits Emma Birt Envigo Hillcrest Dodgeford Lane Belton Loughborough LE12 9TE Envigo s rabbits have always been in high demand and our breeding colony is well established Since the revised Home Office Code of Practice was first published we have been planning and introducing rabbit housing that fully complies with the caging changes while utilising this opportunity to review our procedures and establish best practice for rabbit breeding and supply Any changes had to be carefully considered and evaluated before being introduced to ensure the initiatives were beneficial and did not adversely affect breeding or supply This poster discusses the welfare enhancements that we were able to successfully put in place for our littering rabbits 64 Scientific Programme

Poster Displays Biosecurity enhancement in construction and recycling of isolators Alice Bailie Charles River UK Ltd Manston Road Margate Kent CT9 4LT Use of isolators for breeding and maintenance of laboratory animals continues to be an important technology resource as it provides complete physical separation between the animals housed and the external environment Isolators are commonly used for the maintenance of axenic gnotobiotic immune compromised strains customer animals harbouring pathogens or opportunistic agents and for biohazard containment and provide the highest level of biosecurity and bioexclusion Isolator usage remains an expensive and labour intensive technology relying on the use of sterile consumables rigorous adherence to material entry and exit plus a quality recycling procedure prior to any subsequent usage Those procedures often require the use of high level disinfectant with rapid biocidal effects that may be hazardous to employees This poster will discuss recently made refinements to our isolator recycling process that has resulted in enhanced quality of sterilisation with the benefit of reduction in cost and occupational exposure to chemical agent Development of a CL2 aquatics facility at The Sanger Institute Lynda Westall Wellcome Trust Sanger Institute Wellcome Trust Genome Campus Hinxton Cambridge CB10 1SA With the use of Zebrafish Danio rerio in research continuing to rise the requirements to adapt facilities for housing this species have grown from the general hobbyist setup to the advanced multi recirculating systems available today In many instances the introduction of the aquatics species requires room alterations building management system amendments compliance with regulations differing to that of the mammalian species and even structural modifications Although the design of an aquatics facility has some similarities to that of a rodent area there are critical differences which must be considered Working in collaboration the Wellcome Trust Sanger Institute and The University of Cambridge Department Laboratory of Molecular Biology LMB have created what is believed to be the first CL2 aquatics facility in the UK and possibly in Europe Here we explain the challenges of the system s design room layout health and safety requirements personal protective equipment disinfectant procedures and building management system modifications to comply with legislation and scientific goals Scientific Programme 65

Workshops Each course is CPD accredited Ten workshops will take place over two days Confirmation of your pre booked attendance should be verified on arrival at the Congress Reception All Workshop Sessions are taking place on convention level C2 Please refer to the individual workshops for room names A map showing all room locations can be found in the Notepad and the Congress App TUESDAY 21st MARCH Time Workshop 12 15 14 15 W3 Introduction to Zebrafish Danio rerio 12 15 14 15 W8 IVC environmental health monitoring 3Rs and colony management 14 30 16 30 W5 Severity classification and reporting 14 30 16 30 W9 Playtime for rats WEDNESDAY 9th March Time Workshop 10 30 11 00 COFFEE Trade Exhibition Hall Foyer 10 45 12 45 W1 How to be an AWERB champion 10 45 12 45 W3 Introduction to Zebrafish Danio rerio 10 45 12 45 W7 Using the science of human behaviour to improve animal welfare 10 45 12 45 W8 IVC environmental health monitoring 3Rs and colony management 12 45 14 15 LUNCH Trade Exhibition Hall Foyer 13 15 15 15 W2 Working with minipigs all you ever wanted to know 13 15 15 15 W4 Practical aseptic technique basic 13 15 15 15 W5 Severity classification and reporting 13 15 15 15 W10 Nice to meet you so what do you do for a living 15 00 16 00 TEA Trade Exhibition Hall Foyer 15 30 17 30 W1 How to be an AWERB champion 15 30 17 30 W4 Practical aseptic technique advanced 15 30 17 30 W6 Preparing to present for the first time 15 30 17 30 W9 Playtime for rats Scientific Programme 67

Workshop Sessions Please refer to the Table on page 67 for timings Location Conwy 1 2 hours CPD credit W1 How to be an AWERB champion Presented by Penny Hawkins BSc PhD Deputy Head Research Animals Department RSPCA Wilberforce Way Southwater West Sussex RH13 9RS Animal Technologists already act as valuable members of the Animal Welfare and Ethical Review Body AWERB and this workshop aims to encourage even more active participation It is suitable for those who are already AWERB members and others who are considering becoming involved Topics include l introduction to AWERB l helping the AWERB to fulfil all of its tasks l improving engagement with scientists l i dentifying training needs to help Animal Technologists become active and effective AWERB members l teaching styles Penny Hawkins Penny is Head of the RSPCA Research Animals Department which works to achieve more effective ethical review of animal use and further the implementation of the Three Rs She joined the RSPCA 20 years ago and has served two terms as a member of the Animal Procedures Committee and one on the Animals in Science Committee continuing to sit on the ASC s AWERB Sub committee Penny s main areas of work relate to promoting effective AWERBs and also to refinement for example reducing severe suffering improving housing and care assessing welfare the use of animals in fundamental physiology research telemetry and humane killing The implementation of new UK and European regulations controlling animal use including effective harm benefit assessment and ethical review is also a current priority 68 Scientific Programme

Workshop Sessions Please refer to the Table on page 67 for timings Location Conwy 2 2 hours CPD credit W2 Working with minipigs all you ever wanted to know Presented by Adrian Zeltner LabTech FELASA A and B Customer Support and Veterinary Services Ellegaard G ttingen Minipigs A S Soroe Landevej 302 4261 Dalmose Denmark For any type of work with animals a profound understanding of the species involved is paramount Conducting studies with minipigs is no exception Proper handling and training of the minipig will greatly contribute to the success of the study and animal s welfare We will explore what it means to work with minipigs and any other practical aspects that may arise from the participants Topics include l biology of the minipig l behaviour of minipigs l welfare needs l housing l acclimatisation l handling l dosing l training Adrian Zeltner Adrian has been employed at Ellegaard G ttingen Minipigs since 2005 and currently offers customer support mainly covering the practical aspects like housing for minipigs care welfare sampling and dosing He also lectures in animal training and is engaged in the refinement and development of dosing methods as well as organising and conducting courses workshops and interactive seminars in Europe the USA and Japan Adrian was born in Switzerland where he was educated as a Laboratory Technician at Ciba Geigy Novartis He graduated in 1978 and has also worked for the University of Z rich Cilag Johnson Johnson Sika and been self employed An extensive traveller all across Asia Adrian has also lived in Australia and New Zealand before moving to Denmark in 2004 Scientific Programme 69

Workshop Sessions Please refer to the Table on page 67 for timings Locations Tuesday Beaumaris 2 Wednesday Conwy 2 2 hours CPD credit W3 Introduction to Zebrafish Danio rerio Presented by Jon Faupel BSc Hons 1 and Tommaso Sala2 1 Aquatics Specialist and Account Manager Tecniplast UK Ltd BCM Box 3058 London WC1N 3XX 2 Customer Care Manager Aquatic Line Tecniplast SpA Via 1 Maggio 6 Buguggiate Varese 21020 Milan Italy The use of Zebrafish Danio rerio within research has increased year on year over the past two decades and is now ranked as one of the major species used The environment in which Zebrafish thrive is crucial and the Animal Technologist has a vital role in helping to sustain this This workshop aims to provide an introduction to Zebrafish and managing their welfare within a research environment Topics include l an overview of Zebrafish their origins and general biology l basic husbandry housing and water quality l ill health and disease prevention l nutrition l breeding Jon Faupel Jon s career spans over 10 years within the biomedical research industry from Animal Technician through to Aquatics Product Specialist He has successfully delivered a number of aquatic workshops and training seminars with Tecniplast and on a global scale Jon has a degree in Oceanography from the University of Bristol and prior to joining Tecniplast in 2010 he has worked at Porton Down and the Wellcome Trust Sanger Institute Tommaso Sala Tommaso graduated in 2004 with a degree in Animal Science from the Faculty of Veterinary Medicine at the University of Milan During his studies he spent two year s gaining work experience with a private company involved in the hydrobiology of natural water bodies including lakes rivers and streams enabling him to learn a lot about water chemistry and fish biology including taxonomy breeding and growing wild species He joined Tecniplast in 2006 to support the growth of the newly established aquatic line and is now the Customer Care Manager dealing with everything concerning water quality parameters fish and amphibians biology feeding breeding and rearing as well as training and after care for users of newly installed systems 70 Scientific Programme

Workshop Sessions Please refer to the Table on page 67 for timings Location Beaumaris Suite basic and advanced 2 hours CPD credit W4 Practical aseptic technique basic and advanced Presented by Olga Woolmer DVM MRCVS1 and Alexandros Zervas2 Veterinary Surgeon Royal Veterinary College Royal College Street London NW1 0TU 1 2 Named Come and join us at either or both of our interactive sessions The basic workshop will introduce Animal Technologists to aseptic technique for surgery We will help you to understand the reasons behind use of aseptic technique in surgery whether for long or short term procedures from mice to rabbits to camelids Using an interactive style you will learn the techniques that make up best practice in surgical preparation and practice There is also the chance to see many of the options that are available to you without having to spend a fortune or take a long time preparing your surgical area For the more experienced audience the advanced workshop will cover the more intricate aspects of sole surgery as opposed to working in a surgical team We also welcome your questions suggestions and would like to share your experiences in order to help you optimise your procedures once you re back in your home Institute Topics include basic advanced l pre operative care l sterility of delicate instruments l setting up a surgical area l long term anaethesia l preparing the animal l analgesia l preparation for surgery l post operative care Olga Woolmer Olga works as part of a small team of Named Veterinary Surgeons at the RVC and currently she is the main NVS for UCL but she also travels across the UK to provide NVS services to a number of academic government and commercial establishments Before becoming a member of the RCVS Olga spent a number of valuable years working as an Animal Technologist for GlaxoSmithKline She has a wide range of knowledge and experience of working with different laboratory species in both early discovery and safety assessment projects Alexandros Zervas Alex has always worked in both sections of Laboratory Animal and Small Animal Medicine as a vet As part of the NVS Services Group of the RVC located at University of Oxford he visits institutes around the UK providing clinical services training seminars and assessment for researchers and staff as well as assistance in the preparation of HO related documents and is a member of various committees Currently a PhD student he has received and later facilitated training in Microsurgical techniques at the Laboratory for Research of the Musculoskeletal System LRMS School of Medicine University of Athens Alex s main interest is in animal care welfare design of studies refinement of procedures and the promotion of the 3Rs across Europe and worldwide Scientific Programme 71

Workshop Sessions Please refer to the Table on page 67 for timings Locations Tuesday Beaumaris 1 Wednesday Conwy 1 2 hours CPD credit W5 Severity classification and reporting Presented by Kathy Ryder MB BS BSc MRCP DPhil Inspector Animals in Science Regulation Unit Home Office 2 Marsham Street London SW1P 3DF To examine the process of assessing and reporting severity and examining the challenges of achieving consensus ASPA requires the classification of procedures according to severity during the application for a project licence There is also a requirement to report the actual severity experienced by each animal used in a procedure Both these processes provide opportunity to refine the adverse effects of procedures Consistency of assignment of severity categories across the UK is required so that information provided is accurate and usable Topics include l i dentifying the components within the procedures which may cause pain suffering distress or lasting harm l defining the adverse effects and mitigation l identifying appropriate end points l assigning prospective severity classification la udience response session Turning Point to consider examples of actual severity assessment Kathy Ryder Kathy Ryder trained and worked in London as a doctor with a special interest in cardiology particularly abnormal heart rhythms and sudden death She worked in research using mammals in Oxford for 10 years before moving to the Home Office as an Inspector and will celebrate her 20th anniversary of being with the Home Office in June 2017 Kathy has a wide experience of inspecting establishments with varied ranges of species mostly in Scotland and the North of England and has particular interests in Education and Training Named People Ecotoxicology and Severity For this workshop she will be using her skills as a facilitator and trainer to build confidence accuracy and a teamworking approach to assigning actual severity 72 Scientific Programme

Workshop Sessions Please refer to the Table on page 67 for timings Location Denbigh Suite 2 hours CPD credit W6 Preparing to present for the first time Presented by Diana Baumann BSc Hons RLATG CMAR Head of Reptile and Aquatics Stowers Institute for Medical Research 100E 50th Street Kansas City Missouri 64110 USA This workshop will be tailored towards those who would like to present at a meeting but never have Barriers to giving a presentation include fear of public speaking and not knowing what to talk about or how to talk about it Topics covered in this interactive session will include choosing a topic the preparation process knowing your audience explaining tough concepts and giving the talk itself How adults learn and exercise to overcome nervousness will also be incorporated Attendees will ideally come with an initial idea of a topic on which they would like to create a presentation and hopefully this session will provide the framework to allow them to go out and speak with success Diana Baumann Diana as Head of the Reptile and Aquatic Facility together with the research staff provides Stowers Institute with the highest quality laboratory animal care and support services for non mammalian species This facility which is fully AAALAC accredited faces the unique challenges in providing specialised husbandry and housing for exotic species models including whiptail lizards veiled chameleons Zebrafish and flatworms Diana is also a member of the IAT AALAS LAMA LAWTE and the Zebrafish Husbandry Association and is regularly invited to speak worldwide on her experiences in the unit as well as on other related LAS topics In 2016 she was honoured to receive the LAMA Charles River Medallion Award given in recognition of her distinguished contributions to the field of laboratory animal management Scientific Programme 73

Workshop Sessions Please refer to the Table on page 67 for timings Location Denbigh Suite 2 hours CPD credit W7 Using the science of human behaviour change to improve the welfare of research animals Presented by Suzanne Rogers BSc Hons ChBC International Consultant for Animal Welfare and Human Behaviour Human Behaviour Change for Animal Welfare Community Resource It can sometimes be challenging to engage all staff in the most refined procedures and handling techniques for research animals This two hour workshop will explore how understanding the science of human behaviour change can help you increase your influence and improve the take up of good practices The workshop will be interactive and involve group exercises reflection as individuals and material presented by the facilitator It will include practical sessions to explore ways of applying the concepts to the research animal setting Topics include l t he process of change e g the Theory Of Change planning tool l t he psychology of change exploring motivation barriers habits routines beliefs attitude and group psychology l t he environment for change including organisational culture of care l t he ownership of change e g using participatory methods of education and peer to peer interactions to facilitate change Suzanne Rogers Suzanne worked in science publishing for 10 years initially as a science journalist then as the Managing Editor of Trends in Biotechnology and finally running a set of Trends journals In her spare time she re qualified in animal behaviour and welfare gained extensive practical experience with several animal welfare organisations worked as an equine behaviour consultant and founded Learning About Animals which consists of four elements events equine behaviour animal welfare consultancy and resources In 2007 she became the Programmes Manager of the Companion Animal Unit at WSPA now World Animal Protection managing dog population and working equine programmes A key part of this role was to develop and test participatory methodologies working within communities to lead to a change in the way people manage and care for their animals Suzanne led the move away from a heavy focus on mobile clinics towards prevention through participatory approaches She then became heavily interested in all aspects of human behaviour change and later to reflect the broad applicability of the approach to other species she became the Technical Advisor for Human Behaviour Change Programmes and since 2011 has worked as an international consultant info hbcanimalwelfare com 74 Scientific Programme

Workshop Sessions Please refer to the Table on page 67 for timings Locations Tuesday Beaumaris 1 Wednesday Beaumaris Suite 2 hours CPD credit W8 IVC environmental health monitoring 3Rs and colony management Presented by Patrick Hardy DVM DipECLAM Exec MBA1 and Pete Willan DMS FInstMgt MIAT RAnTech2 1 Director of Veterinary and Professional Services Allentown Inc 165 Route 526 Allentown New Jersey 08501 USA 2 Product Specialist Allentown Europe Ltd PO Box 3056 Reading Berkshire RG1 9UY Combined advances in PCR techniques and innovative IVC exhaust capture systems allowed increasing the sensitivity reliability and practicality of IVC environmental monitoring Furthermore it extends to operational benefits and represents a major opportunity of implementing the 3Rs through a significant reduction of animal sentinel use while addressing the drawbacks related to dirty bedding transfer Topics include l the specificities of a dedicated IVC exhaust capture at cage and rack level allowing efficient sampling l summarises multiple field real condition testing results compared with exhaust air dust swabbing and sentinel based monitoring l the potential benefits in operational management and in implementing both 3Rs and FELASA recommendations for rodent heath monitoring Patrick Hardy Patrick Hardy is the Head of Veterinary and Professional Services Allentown Inc since 2016 He is the company s scientific and veterinary subject matter expert for products and services and responsible for leading veterinary customer support and consulting services facility design and management regulatory compliance health management animal welfare veterinary care gnotobiology biosafety and iocontainment Prior to joining Allentown Patrick was Director of Biological Laboratories at Sanofi Pasteur and of Animal Science Welfare at Sanofi Merial and Sanofi Pharma R D Before joining Sanofi he was Head Veterinarian for Charles River Europe He was a Council member of the Association for the Assessment Accreditation of Lab Animal Care AAALAC International and member of various expert groups and commissions as well as President of FELASA Patrick obtained his DVM from the University of Liege Faculty of Veterinary Medicine and is Board Certified by the European College of Lab Animal Medicine Diplomate ECLAM Pete Willan Pete has been employed in animal technology for the past 45 years in both academia and pharmaceutical facilities starting as a trainee Animal Technician and progressing to Facility Manager and now works as Development and Project Consultant and Product Specialist with Allentown He has been extensively involved in developing animal care and welfare training and design relocation planning and refurbishment of facilities and the design and construction of new buildings An Honorary Member of the IAT since 2014 Pete has experience in branch and council committees and has represented the IAT as a member of the AALAS International Advisory Committee He is dedicated to the spirit of the 3Rs and also is strongly committed to public openness and awareness programmes in the pursuance of good biomedical research in the use of animals Scientific Programme 75

Workshop Sessions Please refer to the Table on page 67 for timings Locations Tuesday Beaumaris 2 Wednesday Conwy 2 2 hours CPD credit W9 Playtime for rats Presented by Kathryn Owen BSc Hons MRes PhD National Centre for the 3Rs NC3Rs Gibbs Building 215 Euston Road London NW1 2BE In 2017 the NC3Rs has decided to spotlight the welfare needs of the laboratory rat Together with AstraZeneca our workshop aims to explore approaches to providing laboratory rats with a complex environment and increased opportunity to exercise We will focus on how Animal Technologists can consider practical implementation within their institution Outputs from the meeting will include a short paper highlighting opportunities and barriers to adoption Kathryn Owen Kathryn is a Programme Manager in Animal Welfare at the NC3Rs where she heads several office led initiatives including mouse aggression and rat enrichment programmes Previously she worked at Imperial Innovations an early stage venture fund building and investing in new start up life science companies from UK academia and also in the pharmacogenomics group at AstraZeneca supporting drug discovery and development activities Kathryn completed a PhD in Matrix Biology from Imperial College London studying the regulation of cartilage degrading enzymes in osteoarthritis and also holds a Master of Research degree in Biological Sciences from the University of Manchester Her first degree was Biochemistry from the University of Birmingham 76 Scientific Programme

Workshop Sessions Please refer to the Table on page 67 for timings Location Denbigh Suite 2 hours CPD credit W10 Nice to meet you so what do you do for a living Presented by Bella Williams BSc Hons DPhil MIKE1 and John Meredith BA2 of Engagement Understanding Animal Research UAR Hodgkin Huxley House 30 Farringdon Lane London EC1R 3AW 2 Head of Education and Outreach Understanding Animal Research UAR Hodgkin Huxley House 30 Farringdon Lane London EC1R 3AW 1 Head Many people who work in life sciences worry about this question but for Animal Technologists it can be particularly difficult The aim of this workshop is to help attendees feel equipped and empowered to have conversations about their work We will explore how we handle this question and give the opportunity to discuss our responses In this era of greater openness can we talk about our work more When is it the right thing to do and when should we avoid the subject Topics include l speaking out what are the risks what are the benefits l dealing with challenge keep talking or walk away l preparing for tough questions l openness in research Bella Williams Bella has been exploring the relationship between science society and communication for over 20 years working through research in both natural and social sciences to consider how ideas about science are communicated to the public and their influencers such as media and policy makers She is currently Head of Engagement at Understanding Animal Research UAR and is responsible for initiatives around member engagement and public engagement both helping UAR members and stakeholders with outreach and reactive initiatives on the use of animals in research and engaging directly with the public on this issue She leads on Openness at UAR working with signatory institutions of the Concordat on Openness on Animal Research to help them build openness into communications strategies John Meredith John Meredith is Head of Education and Outreach for Understanding Animal Research UAR which is a non profit organisation that distributes accurate information about the use of animals in medical veterinary and scientific research and promotes greater openness among universities and organisations using animal models He has led the UAR education and outreach team in creating a speaking programme that has communicated the benefits of animal research to tens of thousands of young people over 300 schools were visited last year as well as providing training and support in public speaking to hundreds of researchers and Animal Technologists across the UK Scientific Programme 77

Social Programme Tuesday 21st March ORIENTATION TOUR 16 45 Never attended Congress before or have come on your own and don t know many people or simply want to know where you are going Then meet us at the Congress Reception for a tour of the venue Afterwards join in the ICE BREAKER CELEBRATING TECH MONTH 17 00 Fun and games thrills and spills a great way to meet old and new fellow Technologists ALL WELCOME Beaumaris Lounge convention level C2 DINNER Served in the Trade Exhibition Hall Foyer convention level C 19 00 Followed by the TRADE RECEPTION until 22 30 Our extremely hospitable Exhibitors always make this a very memorable evening Wednesday 22nd March DINNER 19 30 Served in the Caernarfon Suite convention level C1 Then afterwards be ready for the LEGENDARY CONGRESS QUIZ This is the anticipated tradition sorting the dummies from the anoraks all in a great atmosphere If you prefer an alternative evening there will also be a DISCO The Bar in the Caernarfon Suite and Foyer will stay open until 1 00 am Thursday 23rd March Smart dress jackets and ties are required No jeans t shirts trainers or fancy dress please GALA DINNER DANCE Caernarfon Suite convention level C1 Followed by the ABBA S ANGELS We defy you to not sing along to at least ONE SONG you know And we have a Disco too The Bar in the Caernarfon Suite and Foyer will stay open until 2 00 am Congress Badges must be worn by EVERYONE 78 Social Programme 20 00 02 00

Social Programme Abba s Angels are one of the UK s premier Abba Tribute groups featuring incredibly talented singers and musicians replica costumes and choreographed dance routines offering a most captivating and authentic homage playing all the best known songs of one of the greatest bands of all time SO GET READY ALL YOU SUPER TROUPERS and DANCING QUEENS to take to the floor as we say THANK YOU FOR THE MUSIC Legendary Congress Quiz Back by popular demand and expanded to allow everyone to attend we welcome Ken Applebee as our inimitable Quiz Master Extraordinaire Come along and pit your wits against your fellow delegates and show off your knowledge of the diverse range of topics covered in this unmissable challenge Social Programme 79

Trade Exhibition Exhibitors Index Agenda Life Sciences Learning Curve Development Ltd Allentown Europe Ltd Lomir Biomedical Inc Animal Care Systems Marshall BioResources Animals in Science Education Trust AS ET MMM Medical Equipment UK Ltd Aquaneering Fairfield Controlec Ltd National Centre for the Replacement Refinement and Reduction of Animals in Aston Pharma Research NC3Rs a tune software AG NKP Isolators and Caging Systems Bioquell UK Ltd Ortner Cleanroom Technology GmbH Castium Ltd Plexx BV CCTech R W Associates UK Ltd Charles River Rees Scientific College of Laboratory Animal Science RWD Life Sciences Co Ltd and Technology CLAST S3 Science Recruitment Datesand Ltd SCANBUR Edstrom Industries Serlab Ellegaard G ttingen Minipigs Special Diets Services Envigo STERIS Solutions Ltd Fisher Scientific Surrey Diagnostics Ltd IDEXX BioResearch Sychem Ltd IMPEX Services International Ltd Tecniplast UK Ltd Institute of Animal Technology UNO Roestvaststaal BV IPS Product Supplies Ltd Laboratory Animal Science Association LASA Vet Tech Solutions Ltd LBS Serving Biotechnology Ltd with Noray Bioinformatics SLU and MAXAIR Systems Animal Technology underpinning scientific knowledge 80 Trade Exhibition

Trade Exhibition Trade Exhibition Hall and Foyer Lunch and Refreshments Poster Displays IAT Entrance AS ET LASA NC3Rs CLAST Envigo Allentown LBS Plexx Castium NKP Vet Tech Fisher IMPEX R W Associates Edstrom Fairfield Controlec Agenda Datesand Sychem IDEXX UNO BV Bioquell UK MMM Ltd Medical Aston Pharma Tecniplast Tecniplast a tune Marshall Ortner Cleanrooms Surrey Diag Learning Curve Serlab Animal Care Systems Ellegaard G ttingen Lomir STERIS CCTech SCANBUR RWD LS Allentown Charles River IPS Rees Scientific SDS S3 Science Trade Exhibition 81

Trade Exhibition The Publisher and the IAT accept no responsibility for any claims made by companies in the following entries Agenda Life Sciences Leading the way in Animal Technologist recruitment contract Technologist and animal facility management services since 1996 Developed by Technologists for Technologists Resources why choose Agenda lA genda has the largest database of Technologists seeking career development and research organisations seeking staff our services are free and confidential for all job seekers le xperienced friendly and professional recruitment consultants l f ast and flexible staffing solutions to meet clients needs and to offer a wider range of opportunities for job seekers l c omprehensive skills and preference review service to provide the perfect matches lA genda s highly regarded Welfare First Programme cares for the people who care for the animals including key elements such as a Welfare Contract Welfare First e Newsletter and training and development to provide the support to deliver great animal care and welfare Permanent recruitment services la n expert partner to take the stress out of the hiring process detailed pre employment screening and suitability interviews conducted before you interview l c lient focus underpinned by the Agenda values ISO 9001 for quality of service and ISO 27001 to protect your personal information Contract and temporary Technologist services l c over when you need it for short and long term needs l f ully compliant with the Agency Worker Regulations lo nline Technologist resource occupational health re security screening pet declaration and HR support are provided as standard l t he security of knowing all of our Technologists have signed our Welfare First Contract to ensure they uphold the standards required under the Animals Scientific Procedures Act 1986 lp rovide extensive individual training records for all Technologists to enhance their personal development in line with our Investors in People ethos l2 4 7 365 days a year help line support provided ld etailed e Technologist CV profiles to find your best fit le lectronic timesheets to save time and effort in line with our commitment to ISO 14001 Facilities management services lo ur unique facility management forum provides access to bench marking specific expertise in health and safety GLP operational management strategic development and lean service delivery skills ln o recruitment interview or advertising costs no HR issues l c ompetency based training support and continual professional development Contact us at Agenda Life Sciences PO Box 24 Hull HU12 8YJ T 44 0 8456 445545 International 44 0 1964 671791 F 44 0 8456 445547 International 44 0 1964 671282 E jobs agendalifesciences co uk www agendalifesciences co uk 82 Trade Exhibition

Trade Exhibition Allentown Europe Ltd Allentown Inc is the leading global provider of quality built animal housing solutions and related animal care products to the biomedical research community While being dedicated solely to the laboratory animal science community over the past 48 years we have produced innovative and superior animal housing systems which continue to exceed and define industry standards Our success is based on our strong business integrity exacting attention to manufacturing detail and unparalleled service We assist our clients through facility design and layout installation training and post occupancy service Our products include IVC systems exhaust air dust collection systems bio containment IVC systems biological workstations animal transport units multi species housing wireless IVC monitoring wireless blower control RFID animal census solutions and a wide variety of facility integrated air flow systems and air flow control accessories Contact us at Allentown Europe Ltd PO Box 3056 Reading Berkshire RG1 9UY T 44 0 845 0450243 E info AllentownInc com www AllentownInc com Animal Care Systems Animal Care Systems manufactures the only motor free ventilated rodent caging system in the industry Combining ultra high density with our unique carousel design our onepass low velocity air flow technology fully protects your animals without a turbulent or forced air pattern within the cage Without motors and blowers our caging provides a microenvironment that is free of noise vibration and ultrasound creating a variable free environment Our caging systems do not use electricity and our technology is not disrupted in the case of a power failure a unique feature that distinguishes ACS caging from electrically powered racks With our unique cage filter designs and freedom from electricity ACS racks have the lowest annual cost to operate and maintain in the industry Our systems direct and filter room air through cages and racks directly to the building s HVAC exhaust system This HVAC driven technology ensures allergens waste gases and thermal loads do not move from the cage into the room but rather are directly exhausted out of the room and the cage Our revolutionary motor free direct exhaust method improves air quality for animals personnel and the room We have established a stellar reputation for our custom accessories superior customer service and product support Contact us at Animal Care Systems 7086 South Revere Parkway Centennial Colorado 80112 USA T 1 720 2830177 E info animalcaresystems com www animalcaresystems com Trade Exhibition 83

Trade Exhibition Animals in Science Education Trust AS ET The Animals in Science Education Trust is a charity registered under the UK Law with objectives of advancing education and promoting excellence in the care and welfare of animals used in science The Trust s main activity is providing bursaries to enable people who are involved in the care and welfare of laboratory animals to attend education and training courses so far we have distributed over 90 000 in bursaries In addition to providing bursaries we have made grants to support research projects and educational meetings We provide three educational prizes for the IAT higher education qualifications and from this year we will be sponsoring a prize for the best Tech 2 Tech article in the IAT Journal At this meeting we will be launching the fifth AS ET special travel bursary competition This bursary allows the author of the winning essay to attend the AALAS National Meeting in Austin Texas USA In order to be able to fund these activities we have to raise money Industry suppliers and manufacturers give great support to AS ET and the IAT is a major benefactor We also organise activities to raise money and IAT branches hold fund raising events for us Individuals who share our objective can also donate by signing a standing order to give a minimum of 24 00 a year to AS ET Visit our stand to find out more about our activities how to apply for a bursary and how you can help support our work Contact us at E contact as et org uk www animalsinscienceeducationtrust org uk Aquaneering Fairfield Controlec Ltd Fairfield Controlec Ltd are the UK representatives for Aquaneering Inc designers and manufacturers of high quality aquatics systems Aquaneering s aquatics systems range in size from small stand alone bench top racks for Zebrafish and Xenopus up to extremely large systems with dedicated centralised water treatment over 33 000 Zebrafish tanks is the largest so far In all cases Aquaneering s expertise in water treatment ensures that animals are held in the very highest quality of water and full training in system operation is provided for technicians and end users Systems can be equipped with full critical parameter monitoring systems with alarm outputs including mobile phone SMS messaging email landline and BMS options Fairfield Controlec Ltd provide installation full service support and emergency backup including spare parts stocks for Aquaneering s systems Our staff have a collective experience of over 50 years of design installation maintenance and support of aquatics systems and include marine biologists and control system engineers We can also provide service support and spare parts for most makes of aquatic systems and also offer training and consultancy in all aspects of system operation and troubleshooting Contact us at Aquaneering Fairfield Controlec Ltd London House King Edward Street Grimsby Lincolnshire DN31 3LA T 44 0 1472 268141 F 44 0 1472 243049 E graham willoughby fairfield controlec co uk www aquaneering com 84 Trade Exhibition

Trade Exhibition Aston Pharma Aston Pharma providing solutions and delivering results We offer an unrivalled selection of PPE consumables and supplies from nitrile gloves latex gloves sterile nitrile and latex gloves overshoes mob caps handwash and much more l PPE protection l personal care l disinfection l housekeeping l specialised equipment and facility supplies Aston Pharma is an independently owned company specialising in life science solutions for healthcare laboratories and the pharmaceutical sectors Contact us at Aston Pharma 27 Old Gloucester Street London WC1N 3XX T 44 0 20 7419 5907 F 44 0 871 9181640 E info aston pharma com www aston pharma com a tune software AG tick lab is a tune s software solution for the management of laboratory animal research facilities It covers all relevant processes for compliance operations animal welfare and provides a single point of access to data and functionality to all persons involved from researchers and facility staff to compliance personnel and management tick lab is in use globally in academia industry and public research establishments tick lab includes lm anagement of project and personal licenses l management of training and competency records l animal ordering l colony and breeding management l aquatic management l animal facility management l animal and animal health management l task management l Home Office documentation and reporting l cost accounting tick lab offers lb uilt in flexibility the tick lab framework enables administrators to configure templates forms cage cards reports and even the user interface including labels grid views and field properties l i ntegration capabilities tick lab has been built for integration with the existing application landscape offers a variety of web service interface and supports diverse integration technologies lb rowser independent web application ready for mobile use no client installation required support for all standard browsers on all types of client devices including tablets la udit trail full audit trail capability to fulfil CFR21 Part 11 requirements and to enable GLP validation Trade Exhibition 85

Trade Exhibition l t ick lab from the cloud tick lab is available as a secure fully managed cloud service reducing infrastructure requirements to the browser and the internet connection In synergy with our clients business objectives we lo ptimise work and data flows l c reate transparency for users supporting the 3Rs lg uarantee governance compliance and best practice l l ower expenses and risks Competitively priced a tune s products project solutions and professional services make these goals a reality Contact us at a tune software AG Julius Reiber Strasse 15 64293 Darmstadt Germany T 49 6151 951310 F 49 6151 9513129 E sales a tune com www a tune com Bioquell UK Ltd Bioquell are the world leaders in the use of hydrogen peroxide vapour technology for the bio decontamination of rooms and or facilities With a comprehensive range of equipment consumables services and validation Bioquell assures the highest levels of performance for the maintenance of a safe environment to operate in Whether for routine biodecontamination or emergency outbreak response Bioquell can offer tailored solutions to fit every need whatever the scale of operation Bioquell services range from decontamination of single rooms after invasive maintenance the commissioning of entire facilities to emergency deployments after a breach in the barrier Bioquell s range of equipment includes mobile generators GMP and non GMP as well as a fixed generator option all integrated with Bioquell s gold standard proprietary hydrogen peroxide vapour technology Whatever level of biological safety a laboratory is operating at bioquelling between projects or sessions is a precaution well worth taking Having equipment available to roll in at a moment s notice or perhaps built in to the building management system accidental exposure of the open laboratory to agents can be quickly and easily mitigated with a robust hydrogen peroxide vapour gassing procedure leaving the space clear of dangers In addition to that very large facilities can be routinely bioquelled by outsourcing to Bioquell and allowing our teams to fully manage the process as part of an annual shutdown for example Bioquell also provide hydrogen peroxide vapour integrated walk in and cart to cart transfer chambers for the movement of materials in and out of controlled areas Ensure rogue viruses do not enter the facility via packaging around essential items keeping your research tools safe and free from diseases Bioquell s hydrogen peroxide vapour technology is the clear choice when replacing traditional formaldehyde or chlorine based applications offering fast residue free and repeatable cycles within a sensitive and controlled environment Contact us at Bioquell UK Ltd 52 Royce Close West Portway Andover Hampshire SP10 3TS T 44 0 1264 835835 E info bioquell com www bioquell com 86 Trade Exhibition

Trade Exhibition Castium Ltd Castium Ltd are specialist decontamination experts based in East Yorkshire with over a decade of experience within the life science industry We pride ourselves on giving superb customer service along with bespoke decontamination processes which can be tailored to suit each individual client This ranges from one off bespoke projects to full time contract cleaning and facility maintenance During our 10 years of operating we have been privileged enough to work with some of the biggest pharmaceutical companies in the UK and Europe along with many prestigious universities It is our mission to continue to offer our customers superlative service and peace of mind Please see a list of our services l HPV treatment l pinworm treatment l insect fumigation including mites flies and weevils l facility commissioning and decommissioning l cleanroom maintenance l ethylene oxide treatment ETO l fungal decontamination sporicidal treatments l consultation If you have any further questions about the services we provide then please do not hesitate to visit our trade stand and our helpful staff will be able to answer any questions you may have Contact us at Castium Ltd Crawshaw Park Westfield Lane Fitling Hull HU12 9AH T 44 0 845 9003767 F 44 0 1964 529344 E info castium co uk www castium co uk CCTech Cube Clean Tech or CCTech is a specialist provider supporting the design development and operation of environments for leading research facilities and healthcare institutions CCTech is based in Cambridge and Dublin and partners with leading industry specialists and suppliers to provide a global service We work with Europe s leading universities government research centres national health services plus design and build companies and architects on the design and delivery of sensitive and critical research facilities We advise and directly deliver on key areas such as design support validation and verification commissioning management clinical cleaning and sterilisation burn in and soft landings We are passionate about this sector and deeply involved in the development of the industry With our experience we work as leaders encouraging and inspiring moves towards a more sustainable future through demonstration and education Our business culture encourages open and candid discussion with our clients and stakeholders to generate practical options with the widest possible support base We have developed a strong quality assurance culture in our company and our network of partners to ensure consistency in our work Trade Exhibition 87

Trade Exhibition Our broad range of expertise ensures that new build and retrofit facilities meet the research needs and user requirements We support the compliance process with the relevant industry Codes of Practice and statutory regulations CCTech is focused on the following three bioscience areas lb iomedical and precision to ensure success these laboratories need to be designed and project managed by those who understand the needs and requirements lG MP CCTech believe in providing an efficient and cost effective approach to the validation of new facilities lb io containment CCTech provides key services in delivering new bio containment research laboratories Please visit our website www cctech eu for more information Contact us at CCTech St John s Innovation Park Cowley Road Cambridge CB4 0WS T 44 0 1223 420252 E info thecube eu com www cctech eu Charles River Charles River continues to be the world s largest producer of laboratory animals Our globally standardised research models include mice rats rabbits Guinea pigs hamsters and gerbils As the exclusive UK distributor for The Jackson Laboratory we provide access to over 5000 strains of JAX mice including the highly immunodeficient NSG mouse For nearly 25 years Charles River has delivered genetically engineered models and services to biopharmaceutical companies academic institutions and a host of government agencies Services include customised breeding programmes quarantine space genetic testing rederivation cryopreservation IVF and proof of concept studies Rather than just identifying the problem Charles River 360 Diagnostics is the only comprehensive partner that can offer solutions from prevention to resolution Through the development of innovative solutions like the LTM EZ Spot and PRIA panels our goal is to help you manage your programme effectively and efficiently Charles River provides high quality training and CPD courses including Home Office modules for licence applicants rodents fish and farm animals Our new eLearning platform Charles River Campus provides convenient and cost effective online training for anyone working in the field of laboratory animal science We supply ALZET osmotic infusion pumps catheters and wound clips Our surgical teams can provide study ready animals with a range of surgical alterations Contact us at Charles River UK Ltd Manston Road Margate Kent CT9 4LT T 44 0 1843 823575 E margate enquiries crl com www criver com 88 Trade Exhibition

Trade Exhibition College of Laboratory Animal Science and Technology CLAST CLAST is the working title of the College of Laboratory Animal Science and Technology In September 2015 it took over the provision of the higher education courses from the Institute of Animal Technology although the Institute remains the Awarding Body for the qualifications The higher education programme is designed to prepare technical staff for the challenges of senior and middle management in the profession The overriding aim is to develop an understanding of the importance of providing high standards of animal care and welfare while providing scientists with the means to produce meaningful scientific research results The programme is divided into three stages levels 4 5 and 6 Level 6 is university degree equivalent and provides the education element for election to Fellowship of the Institute of Animal Technology All of the units in the programme can be taken as stand alone CPD units which may be of interest to people who may not be able to commit to the whole programme or who already have Fellowship To learn more come and visit the CLAST stand visit our website www clast org uk or contact us through info clast org Contact us at College of Laboratory Animal Science and Technology CLAST 5 South Parade Summertown Oxford OX2 7JL E info clast org www clast org uk Trade Exhibition 89

Trade Exhibition Datesand Ltd Working for and with our valued customers since 1980 Datesand Ltd has grown into the family business it is today Now offering a one stop shop for all of your facility consumable items Datesand is the only company in our industry to offer a Price Promise Guarantee on most of our lines Consumables l t he widest range of quality bedding and nesting materials with exclusive access to brands such as Tapvei Aspen and The Andersons corn cob range l Europe s widest range of enrichment products l Nestpaks exclusive 3 in1 bedding nesting and enrichment l PPE and janitorial supplies l chemicals and cleaning equipment le xclusive ranges including ClearH2O hydration and nutrition FreshH2O pouched water and NSET non surgical embryo transfer device Technologies lU K manufactured and exclusive to Datesand Mini Thermacage and Mark III Thermacage for animal warming lw orking in an exclusive partnership with TBJ Inc to offer ventilated workstations bedding dispensers surgery and necropsy tables and water bottle fillers l s ervicing and maintenance contracts Environmental lu nique super absorbent polymer products for liquid to gel applications Datesand is now working in partnership with Envigo to offer streamlined diet and consumable product deliveries We look forward to seeing you at our stand at Congress 2017 Follow us on Facebook and Twitter datesandgroup for exclusive news and offers Datesand Caring for those who care for others Contact us at Datesand Ltd PO Box 45 Manchester M11 1XD T 44 0 161 2741080 F 44 0 161 2741089 E sales datesand com www datesand com 90 Trade Exhibition

Trade Exhibition Edstrom Industries Edstrom Industries is the world leading designer and manufacturer of automated watering systems for animals in the pharmaceutical academic and government vivarium for over 45 years We protect animal health and valuable research through automated animal drinking water systems water purification and environmental monitoring Edstrom automated watering systems deliver purified water on demand 24 hours a day eliminating ergonomic injuries and reducing the costs associated with bottle cleaning filling and manipulation Our A160 valve technology is the most reliable on the market The addition of Edstrom FloSense adds monitoring down to the rack level Edstrom water purification and treatment systems help achieve consistent water quality with Reverse Osmosis RO water purification clean system design principles and automated flushing Edstrom recommends RO water for all transgenic rodents Edstrom Pulse CMC provides real time data readings alarming and reporting through an intuitive user interface that puts you in total control of your facility s data Monitor and control your automated watering system and so much more From room and freezer temperatures to differential pressure air flow humidity and light levels Customisable reports and alarm limits ensure your facility s animals are safe Our light control system allows for high low off emergency and red light status and easy control and verification of reverse day night cycles etc All data is time date stamped recorded and available in graphical and CSV format Contact us at Edstrom Industries E uk edstrom com www edstrom com Ellegaard G ttingen Minipigs Ellegaard G ttingen Minipigs EGM is the exclusive breeder of genetically well defined G ttingen Minipigs and has supplied the scientific community for more than thirty years The company has been AAALAC accredited since 1998 and has a high standard of minipig health G ttingen Minipigs are fully accepted by the regulatory authorities such as EMA and FDA and should always be considered when choosing your non rodent model for pharmacology or toxicology as they are often the scientifically correct research model Animal models for human diseases have been developed in this species and used in the safety assessment of many marketed drugs EGM also provides biological specimens from G ttingen Minipigs for in vitro research as well as courses in husbandry handling dosing sampling techniques and training of G ttingen Minipigs Clean pigs for clear results Contact us at Ellegaard G ttingen Minipigs A S Soroe Landevej 302 4261 Dalmose Denmark T 45 5818 5818 E ckt minipigs dk Trade Exhibition 91

Trade Exhibition Envigo Envigo provides essential research services models and products for biopharmaceutical crop protection and chemical companies as well as universities governments and other research organisations Our business is founded on a dedication to customer service and the expertise and experience of our 3 800 people With over 50 locations worldwide we are committed to helping customers realise the full potential of their research and products as we work together to build a healthier and safer world Our customers can be confident that Envigo is dedicated to understanding their challenges appreciating their perspectives and helping them achieve their goals Envigo is a privately held global company with corporate headquarters in the UK and headquarters for its research models and services business in the USA Contact us at Envigo Station Road Blackthorn Bicester Oxon OX25 1TP T 44 0 1869 243241 F 44 0 1869 246759 E rms uk envigo com www envigo com Fisher Scientific Fisher Scientific is the leading supplier of laboratory chemicals safety products and equipment Fisher Scientific distributes own label and branded products to 40 000 customers in the British Isles Republic of Ireland and selected overseas markets Our plant and headquarters in Loughborough employs 450 people Our comprehensive safety product range offers a one stop shop for all your requirements and is designed to meet the needs of a demanding market With over 200 000 product lines and working closely with our suppliers we provide everything from your day to day needs to the most innovative modern technological products required by a world class market Our company shop window is a dynamic fully interactive web catalogue that provides real time stock availability and a considerable range of customer oriented features This is supported by a series of catalogues covering the entire breadth of general laboratory activity In the UK we list over 170 000 products Contact us at Fisher Scientific Bishop Meadow Road Loughborough Leicestershire LE11 5RG T 44 0 1509 231166 E fisheruk quotations thermofisher com www fisher co uk 92 Trade Exhibition

Trade Exhibition IDEXX BioResearch IDEXX BioResearch is a division of IDEXX Laboratories which was founded in 1983 In the last 15 years IDEXX BioResearch scientists have been innovation leaders in laboratory animal diagnostics publishing over 250 scientific articles and developing novel approaches to animal health monitoring such as our Opti Spot blood collection methodology We are your partner in progressing research A global market leader in diagnostics solutions for animal health water and dairy quality l over 6 300 global employees l over 400 scientists pathologists and veterinarians on staff l over 60 locations worldwide l over 280 million invested in R D in the last 6 years Solutions to help you replace reduce and refine Quality research comes from combining innovation with efforts to improve the welfare of animals used in scientific research procedures Partnering with IDEXX BioResearch offers numerous unique technologies that help you enact the principles of the 3Rs while maintaining complete control over your testing Our laboratory animal science experts are easily accessible for consultation and support to assist you when creating monitoring programmes or making important decisions based on your animal s health status Contact us at IDEXX BioResearch Riverside House Riverside Walk Windsor Berkshire SL4 1NA T 44 0 1753 838909 IDEXX BioResearch Moerikestrasse 28 3 71636 Ludwigsburg Germany T 49 7141 64 83 585 E idexxbioresearch europe idexx com www idexxbioresearch com europe IMPEX Services International Ltd IMPEX Services International Ltd have been serving the research industry for 15 years with Europe s largest independent fleet of specially equipped and designed DEFRA registered vehicles Our dedicated team work 24 hours a day 7 days a week to offer a complete handling and shipping service for all laboratory animals biosamples and equipment regardless of your shipping needs Our complete global coverage guarantees you a secure efficient door to door service to or from any destination worldwide Our budget shipping options for smaller consignments offer clients a cost effective alternative with the same excellent level of service and commitment within the UK and across the European continent With a range of vehicles from our eco friendly Minis to large trucks IMPEX really do offer you total logistics solutions We are confident you will be delighted with our services Contact us at IMPEX Services International Ltd PO Box 187 Huntingdon Cambridgeshire PE28 4JF T 44 0 8456 021662 F 44 0 8456 021663 E info impex uk com www impex uk com Trade Exhibition 93

Institute of Animal Technology FOR EMPLOYERS FOR EMPLOYERS h elping employers to maintain the highest standards of animal welfare and global best practice s upporting cutting edge research with highly skilled professional and committed animal technologists s tructured internationally recognised qualifications Register of Animal Technologists and CPD a ccess into the wider research community including government legislators and other professional bodies d iscounted corporate membership network support and social opportunities for animal technologists For more great reasons to join the IAT visit http www iat org uk membership html

Trade Exhibition Institute of Animal Technology The Institute of Animal Technology IAT was founded in 1950 and its purpose is to advance knowledge and promote excellence in the care and welfare of animals in science The IAT recognises and supports the benefits arising from research involving animals and its members are committed to the principle that excellence in animal care and welfare is essential for excellence in science Representing Animal Technologists both within the United Kingdom and around the world the IAT has over 2500 members which includes the vast majority of the UK s Named Animal Care and Welfare Officers NACWOs for which the Institute awards the accredited training on behalf of the Home Office Education qualification and continuous professional development for Animal Technologists are the primary roles of the IAT The IAT is recognised by Ofqual as the Awarding Organisation for its FE and HE levels 2 3 4 5 and 6 qualifications in laboratory animal science and technology During 2016 the IAT in conjunction with the Medical Research Council has established the level 3 Apprenticeship in Animal Technology and is now considering establishing similar for level 4 The IAT s award winning established Career Pathway www iat org uk pathway for Animal Technologists is now widely recognised throughout the UK and has been adopted as a template by other countries Contact us at Institute of Animal Technology 5 South Parade Summertown Oxford OX2 7JL T 44 0 800 0854380 E admin iat org uk www iat org uk Trade Exhibition 95

Trade Exhibition IPS Product Supplies Ltd IPS has been supplying biomedical research facilities with industry leading brands for over ten years We are exclusive European distributors of LabDiet and TestDiet and also produce speciality diets such as DIO High Fat Range AIN Series Tamoxifen Fenbendazole in our modern TestDiet Europe facility here in the UK The LabDiet and TestDiet formulations have evolved as research models have developed and now more and more researchers are relying on the LabDiet and TestDiet products for their studies IPS is also proud to represent Benchguard Lignocel Bedding and other high quality products that compliment your research Contact us at IPS Product Supplies Ltd BCM IPS Ltd London WC1N 3XX T 44 0 870 6001616 E customers ipsltd biz www ipsltd biz Laboratory Animal Science Association LASA To advance scientific understanding and knowledge of the use care and welfare of laboratory animals and promote refinement reduction and replacement LASA persues its aims in a number of ways Promoting the interchange of information through meetings lectures discussions and publications LASA has six sections which together provide a forum to discuss the latest developments in the areas of specialised scientific interest Every year the scientific sections hold section meetings The Annual Winter Meeting is a three day scientific meeting covering a wide range of topics in platform presentations and workshops The meeting also offers great opportunities to network with Trade Exhibitors LASA encourages and facilitates education and training in laboratory animal science This takes place through workshops and the publication of proceedings and best practice guides We welcome applications of membership from individuals institutions and students Contact us at LASA PO Box 524 Hull HU9 9HE T 44 0 8456 711956 F 44 0 8456 711957 E info lasa co uk www lasa co uk 96 Trade Exhibition

Trade Exhibition LBS Serving Biotechnology Ltd with Noray Bioinformatics SLU and MAXAIR Systems As a company heritage and tenacity run through the very veins and DNA of LBS These have played no small part in its success as a leading supplier of diet bedding consumables and services to the biotech industry for the past 48 years Whilst the company takes immense pride in its heritage we recognise that it is only through a relentless and a consistent focus on meeting and exceeding the requirements of our domestic and international customers in the biotechnology industry that we maintain this position We offer a combination of tried and tested products and through a continual process of product development new innovative product solutions All of this is backed through our commitment to ISO 9001 2015 quality assurance customer service and logistics management This is further underpinned and developed through a process of working closely with and understanding our customers needs at which we aim to excel Visit our stand for information and advice on lA niBio animal facility management software covers all your essential needs l r esearch and zoo diets le nvironmental enrichment products l r esearch bedding and nesting material le xtensive choice of small and large hay bale product lw ater resistant protective clothing and safety footwear ld isinfectants and allied products lb espoke irradiated packaging and supplies l t ransit and transport boxes l s pecialist vacuum floor care products lb road range of specialist equipment and products for Animal Technologists lM AXAIR Systems Controlled air purifying respirators Contact us at LBS Serving Biotechnology Ltd PO Box 431 Surrey RH6 0UW T 44 0 1293 827940 F 44 0 1293 782235 E sales lbs biotech com www lbs biotech com Learning Curve Development Ltd Training and CPD that significantly enhance professional competence is more important than ever The Learning Curve provides the highest quality training through courses and workshops for Animal Technologists scientists and support staff at a wide range of pharmaceutical commercial and academic facilities The Learning Curve s impressive and dedicated team give our customers the knowledge and skills required for competent and ethical based science careers We deliver courses at central venues across the UK and at customer premises customising the training to account for local procedures to better meet the establishment needs Courses include lH ome Office PIL A B and C l licensee refresher training l NACWO l RAnTech Trade Exhibition 97

Trade Exhibition l IAT levels 2 and 3 l support staff workshop l GLP and AAALAC awareness l introductions to aseptic techniques technical procedures and necropsy l principles of training mentoring and assessing l award in education and training formerly PTLLS The Learning Curve provides a workplace competency review service Our expert team will review training records assess practical and theoretical competency before providing establishments with a non biased review of their staffs capabilities including any recommendations for further training Contact us at Learning Curve Development Ltd PO Box 140 Ware Hertfordshire SG9 0ZN T 44 0 1763 272588 E info learningcurvedevelopment co uk www learningcurvedevelopment co uk Lomir Biomedical Inc Established in Canada in 1989 with head office and manufacturing facilities based in Quebec Lomir Biomedical Inc is one of the world s leading brands in the design and manufacture of animal jackets for all laboratory animal species infusion systems for rodents and large animals collars restraints animal handling and enrichment products Recognised as a design innovator and manufacturer of high quality durable and easy touse equipment for biomedical and research applications Lomir is the supplier of choice for private contract organisations pharmaceutical companies research institutes universities teaching hospitals biotechnology companies and government institutions Lomir s commitment to pioneering design continuous product improvement technical excellence and customer satisfaction is matched only by their people s dedication to and respect for the wellbeing of research animals The company s range of animal jackets incorporates carefully chosen materials and special features that increase comfort for the subject Lomir s infusion testing and restraint equipment is designed to facilitate ease of use for the handler minimising animal discomfort and stress levels and ultimately protecting the integrity of the procedure Lomir strives to deliver effective and affordable solutions to virtually any challenge it is presented with by its customers For UK enquiries please contact our UK Sales Representative on 44 0 7824 861583 Contact us at Lomir Biomedical Inc UK Office Agenda Resource Management Ltd PO Box 24 Hull HU12 8YJ T 44 0 8456 445545 E stuartl agenda mc co uk 98 Trade Exhibition

Trade Exhibition Marshall BioResources Marshall UK is a division of Marshall BioResources Inc Our UK breeding and holding facility is located in East Yorkshire We offer supplies of Marshall Beagles from our UK holding near Hull If you use ferrets please ask us about our barrier facility which was set up for the production of SPF ferrets flu free We also breed the IFNAR type 1 and type 2 KO mice A129 and AG129 which are in demand for research into vaccines and therapies for viral diseases such as Dengue Fever and Ebola Our SPF Dunkin Hartley Guinea pigs have the highest health status available in the UK being free of CMV and PI3 Our scientific services team offers a highly regarded health screening service and our specialist microbiologist will be on our stand to advise you We are able to carry out health screening at your site or using our collection service your sentinels can be tested in Grimston Biological matrices from a range of donors rodents Marshall Beagles rabbits humans NHPs and farm animals are also available We offer a very quick turnaround of your orders for whole blood plasma serum tissues and many other bioproducts You can also contact us for help with breeding your own colonies or to run non GLP studies Visit our stand to pick up a set of current literature Contact us at Marshall BioResources The Field Station Grimston Aldbrough Hull HT11 4QE T 44 0 1964 527555 E sales marshallbio uk com www marshallbio com MMM Medical Equipment UK Ltd Sterilisation steam generator and disinfection equipment manufacturers MMM Medical Equipment UK Ltd are a subsidiary of MMM GmbH one of the largest European manufactures of sterilisers and disinfection systems with a workforce of over 1000 employees and responsible for many innovations in sterilisation technology The sterilisers we manufacture have a very long life expectancy with reliability playing a major part in the design our strength is our whole life cycle support We can offer single door or pass through double door sterilisers with loading heights of 625mm 390mm or floor level for ease of loading Our standard chamber sizes suit all common IVC and cage racks MMM steriliser chambers are manufactured in house from top grade materials in a range of sizes from 316 litres to 6292 litres plus bespoke units to customers requirements We also offer air tight double skinned barriers for optimum sound and heat insulation very important in animal house situations We have our own project management planning and installation teams based in our UK office and work with architects design teams and planning departments from the initial concept through to final installation commissioning and validation We can incorporate H2O2 VHP generators as part of an automated process cycle as an option on MMM sterilisers Contact us at MMM Medical Equipment UK Ltd Units 2 3 Gateway Drive Business Park Gateway Drive Yeadon Leeds LS19 7XY T 44 0 113 3910717 F 44 0 113 3910503 E sales mmm group co uk www mmm group co uk Trade Exhibition 99

Trade Exhibition National Centre for the Replacement Refinement and Reduction of Animals in Research NC3Rs The National Centre for the Replacement Refinement and Reduction of Animals in Research NC3Rs is a leading independent scientific organisation dedicated to replacing refining and reducing the use of animals in research and testing the 3Rs It supports the UK science base by driving and funding innovation and technological developments that minimise the need for animals in research and testing and lead to improvements in welfare where animals continue to be used It funds research supports training and development and stimulates changes in regulations and practice Primarily funded by government the NC3Rs is also supported by the charitable and private sectors It works with scientists in universities and industry in the UK and internationally Contact us at National Centre for the Replacement Refinement and Reduction of Animals in Research NC3Rs Gibbs Building 215 Euston Road London NW1 2BE T 44 0 20 7611 2233 F 44 0 20 7611 2260 E enquiries nc3rs org uk www nc3rs org uk NKP Isolators and Caging Systems The new NKP Following the re launch in 2012 of the NKP brand we have firmly established the company as a major supplier of animal housing systems to the life science industry Also NKP now offer flexible isolator systems and servicing through our partnership with Envigo Manufactures and suppliers of the following Cages la ll existing NKP cages are still available in polypropylene polysulfone polycarbonate and polyclear for all species l stainless steel lids l aluminium or stainless steel cages for rabbits Guinea pigs cats and marmosets l metabolism cages all styles l floor pens and enclosures for large animals l bespoke design service for all projects Racking l racking for all NKP cages is made in aluminium and stainless steel Trolleys l trolleys are made to individual design specifications Flexible isolators l full stainless steel framed flexible isolator systems l comprehensive technical services department to carry out all servicing requirements Other equipment l a variety of drinking bottles rubber bungs nozzles and melamine tops l mouse nest boxes in various colours l filter tops for the NKP cage range 100 Trade Exhibition

Trade Exhibition l food bins and dollies l food hoppers l animal carrying cases and enrichment products l drug security cabinets l allergen containment enclosures l cleansing stations Contact us at NKP Isolators and Caging Systems PO Box 10131 Coalville Leicestershire LE67 0DZ T 44 0 800 1123047 E info northkentplastics co uk www northkentplastics co uk Ortner Cleanroom Technology Ortner is an Austrian based manufacturer of standardised and custom made equipment and systems for cleanroom applications The company focuses on the fields of biomedical life science and pharmaceutical research and production Founded in 1985 Ortner has now 130 staff with its own production facilities and proven R D capabilities in decontamination systems for rooms materials and personnel Examples of our product range include Material transfer locks l decontamination barrier locks l spraying locks l material transfer hatches Personnel locks l air showers l wet showers Rigid isolators l aseptic isolators l robotic isolators l RABS barrier systems Decontamination technology l ISU H2O2 generators for hydrogen peroxide disinfection l Genny formalin generators l distribution nozzle systems For further details or to arrange a visit please contact our UK and Ireland Business Manager Glyn Selway at glynselway aol com or telephone 44 0 7593 929006 Contact us at Ortner Cleanroom Technology GmbH Uferweg 7 9500 Villach Austria T 43 4242 311 660 42 F 43 4242 311 600 4 www ortner group com Trade Exhibition 101

Trade Exhibition Plexx BV Plexx BV is the sole European representative for BioMedic Data Systems Lab Products Inc and E Z Systems Euthanex With nearly 30 years experience in the pharmaceutical and biomedical industry we have a proven track record of providing high quality products and outstanding customer service Animal identification Injectable transponders give the option to programme unique identification codes as well as reading body temperature Individually ventilated micro isolator systems Protect both your staff and animals with our positive cage in a negative rack design Ask about our unique OneCage and the SuperMouse750 1800 Econo cage disposable system The Econo cage is a completely disposable caging system that has been designed to fit with the SuperMouse750 ventilated racks Hydropac Innovative delivery of water to rodents using on site produced pouches and drip free single use valves Anaesthesia equipment The E Z anaesthesia systems offer user friendly simple operation equipment with a level of precise automation that minimises operator error Automated home cage euthanasia systems The Euthanex product range offers automated home cage euthanasia with CO2 for small medium and large numbers of cages at the press of a button Metabolic cages Simple and easy to use as it is made up of only eight parts Conventional caging Cages are available from stock and can be used interchangeably with your existing European cages These can be supplied in polycarbonate or polypropylene Environmental enrichment Special diets treats and toys for all laboratory animal species Contact us at Plexx BV PO Box 86 6660 AB Elst The Netherlands UK Office T 44 0 800 2289460 E uk plexx eu www plexx eu R W Associates UK Ltd ARMIS is the proven software solution to automate your biological service requirements and is growing in capability see our overview video on the trade stand or on our home page at www armis co uk We have four flavours of our intuitive ARMIS ARC workstation rodent aquatic amphibian and cryopreservation rederivation The ARC workstations operate on traditional desktop PCs laptops or tablets The researchers unit staff enterprise management and departmental controllers have their own web client that interacts and reports on transactions captured at the ARCs 102 Trade Exhibition

Trade Exhibition Our ARCs support automatic cage tank recognition using RFID or barcode technology They can connect to other peripherals such as printers weighing scales using Bluetooth The ARCs capture data using on screen wizards as animal work occurs There is no need for paper or a keyboard Ruggedised and waterproof variants can be supplied Labels are produced when required at the cage tank in either 1D or 2D barcode formats All data collected automatically completes the annual Home Office return to the researcher s web client ARMIS forges a direct link between the researcher and their animal colonies via the web The researcher is able to track monitor and issue work requests such as genotyping pairings and disposals in real time without the need to breach the animal unit bio security barriers New for 2017 we had added experiment notebook to the researcher web We have significantly enhanced our training and competency ARMIS month end now runs 100 hands free overnight We now support contract research by offering the capability to charge for rooms equipment and Technologist time in addition to all animal cage tank costs ARMIS is highly scalable and is capable of running a one PC operation all the way up to the largest multi unit enterprise spread over numerous locations It does far more than can be described here but we can state that you do not need capital expenditure to use ARMIS We charge a simple monthly combined license support fee priced upon the size of your business For a demonstration please visit the stand at any time Contact us at R W Associates UK Ltd St John s House 5 South Parade Summertown Oxford OX2 7JL T 44 0 844 8004128 E contact randw biz www armis co uk Rees Scientific Rees Scientific specialise in monitoring temperature in refrigeration freezing and incubation lighting humidity as well as providing automated watering for animal laboratories Rees Scientific provides automated environmental monitoring to a limitless number of applications in pharmaceutical and laboratory animal research making us the standard by which other monitoring systems are judged As an ISO 9001 2000 company and fully FDA 21 CFR 11 compliant Rees Scientific is constantly upgrading policies procedures and protocols to comply with today s highly regulated environments Automated daily printouts alarm notification audit trails and complete data encryption are just a few of the standard features that help you meet your AAALAC FDA MHRA and Home Office regulations Contact us at Rees Scientific 1007 Whitehead Road Ext Trenton New Jersey 08638 USA M 44 0 7748 185307 E jtelfer reesscientific com www reesscientific com Trade Exhibition 103

Trade Exhibition RWD Life Science Co Ltd We specialise in anaesthesia physiological and surgical equipment used by veterinarians and pre clinical researchers Our mission is to provide high quality products and integrated solutions for our customers with prompt and professional support For more information about our supplies such as the anaesthesia machine ventilator stereotaxic instrument syringe pump cannula system and surgical tools please check our website www rwdstco com Contact us at RWD Life Science Co Ltd No 1 Qimin Road Nan Shan District Shenzhen China T 86 0755 86111286 Ext 8302 E wull rwdmall com www rwdls com S3 Science Recruitment We are the largest supplier of Animal Technologists in the life sciences sector since we opened our doors in 2002 Our success is simple a highly skilled recruitment team that pulls together over 20 years recruitment experience and a mission statement at the forefront of all we do that all great companies are only as good as their staff Our priority is to source the right candidate with the right skills for your organisation We have become the preferred or sole recruitment agency to many of the UK s leading scientific organisations and aim to work with many more over the coming years Whatever the level of staffing from auxiliary licensed Technologists to managers we know that today s placement will be a part of tomorrow s success for our clients Talk to us today and find out how we can provide you with permanent temporary or contract animal sciences staff We want to be a key part of your success and hope you can share in our goal of recruitment excellence Contact us at S3 Science Recruitment BCM Box 1899 London WC1N 3XX T 44 0 844 8844696 E info s3science com www s3science com 104 Trade Exhibition

Trade Exhibition SCANBUR SCANBUR has specialised in equipment for use at in vivo animal research facilities since 1968 A policy of development and constant product improvement has created a unique highquality product range SCANBUR offers a range of products from air handling units ensuring very accurate air humidity in IVCs to air showers cabinets for cages and UDF LAF cabins for cage handling All products are designed with the clear focus on helping our customers achieving l high scientific quality l best in class working environment l optimum animal welfare l unique cost of ownership Primary markets are the Nordic Countries the UK and Central Europe and we are a trusted supplier to the pharmaceutical and biotech industries as well as to leading universities ScanClime ECO for Scantainers and IVCs A mobile and compact unit which offers plug and play air handling and humidification for animal housing systems Provides humidity control with unrivalled accuracy promoting better animal welfare more consistent research results and improved flexibility In addition the cost of humidification can be reduced by up to 80 ScanFlow ECO HEPA filtered laminar air flow cabins ensuring protection of animals staff and environment Enables unhindered efficient and safe working practices Low noise level Multi purpose cabin cage change cage cleaning procedures etc Air shower ECO High powered HEPA filtered unit for efficient access control between different areas Designed specifically for effective use in laboratory animal units Extensive documentation Scantainer Renowned ventilated cabinet available in a range of sizes A secure cabinet which gives protection to both animals and staff Available as independent units or for use with ScanClime Warming cabinets A range of advanced high quality temperature controlled cabinets offering safe uniform and stable temperature Operating tables Downflow benches tables with water heated Corian surface A range of options is available Contact us at SCANBUR Silovej 16 18 2690 Karlslunde Denmark T 45 5686 5600 E info scanbur com www scanbur com Trade Exhibition 105

Trade Exhibition Serlab Since 2003 Serlab has been a reliable supplier of bedding material diet and enrichment products in France We have now our own production of softwood bedding and virgin cellulose huts and shelters We also have permanent stocks of corn cob bedding and aspen chips All products are available in autoclavable or irradiated packaging Serlab also has stocks of extruded and pelleted diet irradiated autoclavable or standard for mice and rats rabbits swine and primates Plastic clean and affordable one way pallets are available on demand We are happy to inform you that deliveries within the UK will be available soon You can rely on Serlab to bring you the most accurate response to your daily and urgent needs New We have unbeatable prices for GLP red mouse tunnel Contact us at Serlab 100 rue Louis Blanc B timent Berlin Lot 7B 60160 Montataire France T 33 1 39 09 14 14 F 33 1 30 37 73 13 www serlab fr Special Diets Services Special Diets Services registered to ISO 9001 2008 and GMP is the largest supplier of laboratory animal diets in Europe and the only dedicated manufacturer in the UK For over four decades SDS has been supplying research establishments and breeders worldwide and we have gained an international reputation for the quality of our diets and manufacturing and storage facilities As research diets are our core business SDS has the formulations packaging and flexibility to suit all your requirements We have a global network of distributions so local supply is an option SDS has a professional technical team who are experts in the field of research animal nutrition Contact us at Special Diets Services PO Box 705 Witham Essex CM8 3AD T 44 0 1376 511260 F 44 0 1376 511247 E info sdsdiets com www sdsdiets com 106 Trade Exhibition

Trade Exhibition STERIS Solutions Ltd STERIS Corporation is a leading global manufacturer and supplier of infection control products formulated chemistries innovative technologies and technical support services Our comprehensive product portfolio is used extensively throughout the pharmaceutical research healthcare and industrial markets and provides our customers with a total solution to maximise productivity integrity of research and manage contamination control issues STERIS is uniquely positioned to address these challenges with an integration of capital equipment including autoclaves washers effluent bio decontamination systems water processing systems formulated chemistries including detergents disinfectants sterility assurance products and a technical support services network STERIS also provides bio decontamination services to our customers where we can respond to any contamination challenges on a routine preventative or emergency basis as well as to support infection control programmes and protocols For bio decontamination services STERIS typically deploy a combination of formulated chemistries sterility assurance products and the use of STERIS VHP Vaporised Hydrogen Peroxide technology as a fumigant VHP technology was developed by STERIS over 20 years ago It is a dry gaseous process used for the bio decontamination of enclosures rooms critical areas HVAC system safety cabinets and other laboratory equipment Contact us at STERIS Solutions Ltd Bridgwater House Jays Close Viables Basingstoke Hampshire RG22 4AX T 44 0 1256 840400 F 44 0 1256 866501 E ukirelandLS steris com www sterislifesciences com Trade Exhibition 107

Trade Exhibition Surrey Diagnostics Ltd Surrey Diagnostics Limited SDL specialises in providing independent screening services for laboratory animal health monitoring Our staff have a wealth of experience in microbiology serology molecular biology and veterinary pathology Through this expertise SDL can provide consultancy services in all aspects of laboratory animal science SDL understand the importance of developing and maintaining a comprehensive health monitoring programme for laboratory animals and recognise that it is a fundamental part of successful research We also aim to provide customer service that is second to none and continually review and improve this Our aim is to give customers the best possible scientifically accurate health monitoring service on the market at a fair price We use the latest appropriate and proven technologies such as multiplex serology and real time PCR to achieve this We advocate a multidisciplinary approach to health monitoring using both conventional methods and live sample techniques to reduce the numbers of animals used whilst maintaining reliability Our enviroscreen service offers a full environmental monitoring service including surfaces air water consumables and laboratory animal allergen LAA monitoring The latest additions to our portfolio of environmental cleaning products are our activated water systems both portable and static for cleaning surfaces floors or providing animals with clean pathogen free water plus many many other uses All at the fraction of the cost of traditional disinfection and cleaning products We also offer a range of air quality management solutions through technologies which are proven to reduce allergens odours micro organisms volatile organic compounds and dust in the environment SDL is the distributor for the latest generation of proven photocatalytic oxidation PCO technologies in the UK and Ireland Please call 44 0 1483 266533 or email marks biokker uk for further information Surrey Diagnostics Ltd is an ISO 9001 accredited company Contact us at Surrey Diagnostics Ltd PO Box 156 Cranleigh Surrey GU6 8ZU T 44 0 1483 268300 F 44 0 1483 266537 E alistair sdl btconnect com E andy sdl btconnect com M 44 0 7778 010184 M 44 0 7870 534617 www sdl uk net 108 Trade Exhibition

Trade Exhibition Sychem Ltd Disinfection sterilisation and decontamination specialists Sychem are specialists in the manufacturing installation and maintenance of equipment and speciality chemical used within the healthcare and life science industry becoming well known for maximum flexibility and outstanding customer service Over the years Sychem continue to raise the bar on standards within the industry as the leading supplier to UK biomedical laboratories and private medical institutions Sychem offer a wealth of knowledge and experience in innovative and competitive solutions installing and maintaining washer disinfectors autoclaves and dispensing systems to biomedical facilities hospitals GMP facilities and laboratories With an ever growing reputation as one of the premium providers of disinfection sterilisation and decontamination products and services Sychem continuously strive to improve and deliver the highest level of service and support to the industries we serve Thanks to a large team of engineers 11 of whom are external support engineers covering the whole of the UK and through working extensively with our manufacturing partners Sychem aim to continually develop cutting edge equipment to ensure our clients are at the forefront of their sector This year 2017 Sychem launch a campaign to minimise microbial risk and avoid biosecurity breach in the healthcare and life science industry by aiming to raise awareness within the sectors Sychem s focus is to intercept the transmission pathways and to increase the control against microbiological contamination in the health and research facilities around the UK Combining research and innovation Sychem offer a healthier and safer environment providing the solutions that meet the quality and safety parameters requested from the respective sectors By working directly with the end user Sychem identify the level of risk posed and introduce the most appropriate cleaner disinfectant and decontamination solution to minimise the microbiological risk faced within each facility Sychem Environment ultra control protect VHP Generators BioReset SMART PLUS PRO Contact us at Sychem Ltd Highcove House Victory Close Chandlers Ford Hampshire SO53 4BU T 44 0 845 6446824 E info sychem co uk www sychem co uk Trade Exhibition 109

Trade Exhibition Tecniplast UK Ltd The perfect partnership for your laboratory animal equipment With a passion for innovation Tecniplast have been at the heart of housing solutions for laboratory animals for over 60 years The team continues with their commitment to the industry forming the perfect partnership for all of your laboratory animal equipment needs The key factors of Tecniplast international success are an acute awareness of the continuous evolution of housing facility needs and the capability to design develop and integrate products in house Our constant investment in tooling technologies automation production capability stock availability staff recruitment and training together with the ISO certified quality and environment management systems stand clearly in favour of a company that has led the field since the early 1950s The range consists of l animal caging for all laboratory species including IVCs and conventional caging l digital ventilated caging the latest technology for your animal facility l aquatics solutions now including a truly innovative Tritone automated fish feeding l laminar air flow technology products include cage changing stations bio safety stations downflow booths bedding disposal systems and air showers l washing disinfection and logistics equipment ranging from bottle washers and fillers rack washers cabinet washers and tunnel washers decontamination locks l automation from partial to fully automated systems to assist with ergonomics standardisation of procedure and throughput Tecniplast founded in 1949 remains Europe s premier manufacturer of specialist laboratory animal equipment Be sure to visit us at our stand to view our latest innovation products Contact us at Tecniplast UK Ltd BCM Box 3058 London WC1N 3XX T 44 0 845 0504556 F 44 0 845 0504557 E info tecniplastuk com www tecniplastuk com UNO Roestvaststaal BV The identification of individual laboratory animals has become more and more important Until recently it was very expensive to introduce the use of RFID transponders into your facility this has now changed UNO can offer you three types of transponders and matching readers all at very reasonable costs Our programme also includes a number of readers varying from a simple hand held reader that just shows you the transponder number to a sophisticated reader and software combination to introduce not only the transponder number but also a number of observations codes etc Last but not least we are happy to introduce our caliper system which allows you to log information onto the data sheet such as ID number weight and for example the measured tumour growth More information on this is available on request UNO is a well known supplier of a wide range of housing products for the laboratory animal market Next to our standard line of housing products UNO has a very successful engineering department which is constantly working to improve the quality of the products and integrating specific customer needs into standard products The demand for anaesthesia equipment that can be used for small laboratory animals has increased substantially Following this trend UNO has been and still is actively involved in the design and manufacturing of complete anaesthesia systems even for the smallest animals We aim 110 Trade Exhibition

Trade Exhibition to not only supply the products but make sure that once the product arrives at your facility the know how about setting up and using the system are also available UNO provides a wide range of products and services to help you as a laboratory researcher to obtain the most suitable and fitting infusion set up for your goal A range of handling restraint and capture equipment is available in order not only to safeguard personnel while handling animals but also to handle the animal in a safe and secure way Contact us at UNO Roestvaststaal BV PO Box 15 6900 AA Zevenaar The Netherlands T 31 316 524451 F 31 316 523785 E info unobv com www unobv com Vet Tech Solutions Ltd Vet Tech Solutions is a company that prides itself with going that extra mile for all its customers Since its inception 15 years ago Vet Tech continually endeavours to meet customer demands and to exceed expectations Our in house technical team are here to help with design manufacture and installation of a huge range of biomedical equipment whether it is a mainstream item or that difficult piece that you just cannot find Our design team work with Solidworks 3D CAD to help you visualise the product you are receiving We offer a wide range of anaesthetic equipment from basic models to more advanced systems These can be manufactured to your requirement using cylinder piped gases or more recently the new cleaner way of working with oxygen concentrators We have carried out many installations of downdraught tables to include anaesthetics and or C02 as part of a system We are specialists in producing home cage euthanasia systems all following the latest Schedule One guidelines All systems are pre set for ease of use no calculating flowrates required Systems can also include a pre anaesthetic cycle if required Options of mobile bench mounted designed for all the major cage manufacturers For all the equipment we produce we offer service contracts carried out by our dedicated specialist team of engineers to fully maintain your equipment We are specialists in working with materials such as stainless steel Perspex polycarbonates acrylics and Trespa so we are waiting to hear your ideas to work together on any projects you may have We also represent l Optilia a range of HD camera systems l Dycem a decontamination flooring system l joint developer of the CurVet Rat Training Aid CITA We are extending our range at this Congress with new anaesthetic systems so please do come along and see us Contact us at Vet Tech Solutions Ltd Unit 17 Daneside Business Park Congleton Cheshire CW12 1UN T 44 0 1260 274333 F 44 0 1260 278822 E info vet tech co uk www vet tech co uk Trade Exhibition 111

IAT Congress 2017 Trade Competition

CONGRESS Congress 2017 Congress 2017 21st 24th March 2017 www iat org uk 2017 21st 24th March 2017 Animal Technology underpinning scientific knowledge