2. Antihypertensive Agents
Antihypertensive agents such as clonidine and guanfacine may be
prescribed alone or with a stimulant to manage the symptoms of ADHD,
especially in children with tics.
These drugs help with impulsivity, sleep problems, frustration tolerance,
They do not have any known effect on inattention.
Common adverse effects include (1) drowsiness, (2) dry mouth, and (3)
Antidepressants may be used in managing ADHD, especially if comorbid
diagnoses are suspected.
Tricyclic antidepressants, such as desipramine and imipramine improve
concentration, mood, and hyperactivity and help regulate emotional ups
It is important to monitor cardiac activity, especially in children, when
patients are taking these drugs.
SSRIs, such as paroxetine and fluoxetine are used primarily when mood or
anxiety disorders are thought to coexist.