Frequently Asked Questions!
What Should I Expect?
It takes about 3 to 6 months for your system to fully adapt to the hormones. During this adjustment period, the most
common symptoms you may experience may be headaches, slight weight gain due to bloating, and breast tenderness.
Other symptoms are listed on your calendars as well. All of these symptoms correlate with too much or too little of
estrogen and/or progesterone. If you are experiencing more negative symptoms than expected, please consult with your
doctor right away in case your dose needs to be adjusted.
When Should I Expect to Have My Period?
If you have a uterus, you should expect to have a period (or bleed) between Cycle Day 25 to Cycle Day 2 of your cycle. A
28 day cycle is only an average cycle for all women; each woman’s menstrual cycle length is different. If at anytime you do
have a period, which is a bright red bleed, you will automatically start your calendar at Cycle Day 1 again.
This means that if you are on the Lunar Calendar and you start your period on any other day than Lunar Cycle Day 1, you
will have to revert to the Personal Calendar since you are not following the lunar cycle anymore. You will then mark the
first day of your period as Cycle Day 1 on your Personal Calendar.
Spotting may also occur while you are on the BioRhythms system. Spotting is light pink or brown; not bright red. If you
do spot before Cycle Day 21, mark it on your calendar and apply 2 extra lines of progesterone to your labia twice daily to
stop the spotting, and continue to do so for one day only. This may stop the early spotting. If the spotting continues to
become a bright red bleed, stop the progesterone all together, and let your period happen. You will mark that day as
Cycle Day 1 again, and report to your doctor so he/she can advise you on how to adjust your dose due to your early
When Should I Get My Blood Tested?
You should have your blood tested by the third month, and then every 6 months thereafter. You should have your blood
tested for both estradiol and progesterone on Cycle Day 12 and 21. There have been many reported instances of
hormone creams on the skin contaminating the blood sample, and thus negatively affecting the results of the blood test.
Therefore, to ensure that your lab results are accurate and consistent with every blood draw, you should either:
Have your blood testing done first thing in the morning BEFORE you apply any hormones, or
Apply your hormones on an area where the blood draw needle will not enter your skin (e.g. thighs, back of knees,
etc.), THEN 3 to 4 hours later, have your blood testing done, and make sure to notify the lab technician to draw blood
from a skin area that has NOT been contaminated with hormone creams that day.
What Medications Should I Not Take?
You should avoid medications, supplements, or herbs that work on hormone receptors because they may hinder the
effect of the hormone creams. Key supplements or herbs that should be avoided are those that are used to help with
menopausal symptoms, such as black cohosh, soy foods and supplements, phytoestrogens (isoflavones and lignans), red
clover, evening primrose oil, chastetree, dong quad, ginseng, and DIM (indole-3-carbinol). Medications that should not be
used while on hormone creams also include anastrozole, letrozole, exemestane, raloxifene, tamoxifen.
This is only a preliminary list. Always check with your doctor and/or pharmacist if any of your current medications may
interact with the hormone therapies.